Defective innate immunity in inflammatory bowel disease: a Crohnʼs disease exclusivity?

Genome sequence of adherent-invasive Escherichia coli and comparative genomic analysis with other E. coli pathotypes

(2010) John HE Nash et al.   BMC GENOMICS

Crohn’s disease of the colon: ultrastructural changes in submuscular interstitial cells of Cajal

(2010) Jüri J. Rumessen et al.   CELL AND TISSUE RESEARCH

Long‐Term Antibiotic Treatment for Crohn's Disease: Systematic Review and Meta‐Analysis of Placebo‐Controlled Trials

(2010) Martin Feller et al.   CLINICAL INFECTIOUS DISEASES

Complications of Tumor Necrosis Factor–α Blockade in Chronic Granulomatous Disease–Related Colitis

(2010) Gulbu Uzel et al.   CLINICAL INFECTIOUS DISEASES

Mycobacteria in Crohn’s disease: how innate immune deficiency may result in chronic inflammation

(2010) Jean-Daniel Lalande et al.   Expert Review of Clinical Immunology

Atypical mycobacteria: showerheads, anti-TNF therapy and Crohn’s disease

(2010) Alka A Desai et al.   Expert Review of Clinical Immunology

Stem cell treatment for Crohn’s disease

(2010) Julián Panés et al.   Expert Review of Clinical Immunology

Manifestaciones gastrointestinales en pacientes con inmunodeficiencias primarias que cursan con déficit de anticuerpos

(2010) Rubén Díez et al.   Gastroenterologia y Hepatologia

ATG16L1 and NOD2 Interact in an Autophagy-Dependent Antibacterial Pathway Implicated in Crohn's Disease Pathogenesis

(2010) Craig R. Homer et al.   GASTROENTEROLOGY

Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: results of a phase I study

(2010) Marjolijn Duijvestein et al.   GUT

Phase I trial of sargramostim in pediatric Crohnʼs disease

(2010) Judith R. Kelsen et al.   INFLAMMATORY BOWEL DISEASES

Association of the NOD2 genotype with bacterial translocation via altered cell–cell contacts in Crohnʼs disease patients

(2010) Katrin Kosovac et al.   INFLAMMATORY BOWEL DISEASES

Inflammatory bowel diseases in patients with adaptive and complement immunodeficiency disorders

(2010) Daniel J.B. Marks et al.   INFLAMMATORY BOWEL DISEASES

Therapeutic strategy in p47-phox deficient chronic granulomatous disease presenting as inflammatory bowel disease

(2010) Folke Freudenberg et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Abnormalities in the Handling of Intracellular Bacteria in Crohnʼs Disease

(2010) Pierre Lapaquette et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Human  -Defensin 2 and 3 and Their Mouse Orthologs Induce Chemotaxis through Interaction with CCR2

(2010) J. Rohrl et al.   JOURNAL OF IMMUNOLOGY

Common Polymorphisms in theNOD2Gene Region Are Associated with Leprosy and Its Reactive States

(2010) William Richard Berrington et al.   JOURNAL OF INFECTIOUS DISEASES

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

(2010) Matthew P. R. Berry et al.   NATURE

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

(2010) Thomas B Clarke et al.   NATURE MEDICINE

Delayed Resolution of Acute Inflammation in Ulcerative Colitis Is Associated with Elevated Cytokine Release Downstream of TLR4

(2010) Farooq Z. Rahman et al.   PLoS One

The immunopathogenesis of Crohn's disease: a three-stage model

(2009) Gavin W Sewell et al.   CURRENT OPINION IN IMMUNOLOGY

Mechanisms and Functional Implications of Intestinal Barrier Defects

(2009) Le Shen et al.   DIGESTIVE DISEASES

Course of inflammatory bowel disease in patients infected with human immunodeficiency virus

(2009) Nikos Viazis et al.   INFLAMMATORY BOWEL DISEASES

MDP-NOD2 stimulation induces HNP-1 secretion, which contributes to NOD2 antibacterial function

(2009) Jesus K. Yamamoto-Furusho et al.   INFLAMMATORY BOWEL DISEASES

Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease

(2009) Andrew M. Smith et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Revisiting Crohn's disease as a primary immunodeficiency of macrophages: Figure 1.

(2009) Jean-Laurent Casanova et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activation of innate immune antiviral responses by Nod2

(2009) Ahmed Sabbah et al.   NATURE IMMUNOLOGY

T cell–intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii

(2009) Michael H Shaw et al.   NATURE IMMUNOLOGY

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

(2009) Rachel Cooney et al.   NATURE MEDICINE

Genomewide Association Study of Leprosy

(2009) Fu-Ren Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inflammatory Bowel Disease in CGD Reproduces the Clinicopathological Features of Crohn's Disease

(2008) Daniel J B Marks et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Phagocyte dysfunction and inflammatory bowel disease

(2008) Farooq Z. Rahman et al.   INFLAMMATORY BOWEL DISEASES

Personal genomes: The case of the missing heritability

(2008) Brendan Maher   NATURE

Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis

(2008) Andre Franke et al.   NATURE GENETICS

Common variants in the NLRP3 region contribute to Crohn's disease susceptibility

(2008) Alexandra-Chloé Villani et al.   NATURE GENETICS

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS