Cancer-associated fibroblasts in intrahepatic cholangiocarcinoma

Development of a Fully Human Anti-PDGFRβ Antibody That Suppresses Growth of Human Tumor Xenografts and Enhances Antitumor Activity of an Anti-VEGFR2 Antibody

(2015) Juqun Shen et al.   NEOPLASIA

Discovery of Small Molecule c-Met Inhibitors: Evolution and Profiles of Clinical Candidates

(2012) Ted Underiner et al.   Anti-Cancer Agents in Medicinal Chemistry

Pharmacological tools for lysophospholipid GPCRs: development of agonists and antagonists for LPA and S1P receptors

(2010) Dong-Soon Im   ACTA PHARMACOLOGICA SINICA

SDF-1:CXCR4 Axis Is Fundamental for Tissue Preservation and Repair

(2010) Marc S. Penn   AMERICAN JOURNAL OF PATHOLOGY

Epithelial-Mesenchymal Transition Induced by Transforming Growth Factor-β1/Snail Activation Aggravates Invasive Growth of Cholangiocarcinoma

(2010) Yasunori Sato et al.   AMERICAN JOURNAL OF PATHOLOGY

Epithelial-Mesenchymal Transition Induced by Hepatitis C Virus Core Protein in Cholangiocarcinoma

(2010) Tianyu Li et al.   ANNALS OF SURGICAL ONCOLOGY

Hypoxic preconditioning advances CXCR4 and CXCR7 expression by activating HIF-1α in MSCs

(2010) Hongbao Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Important role of integrins in the cancer biology

(2010) R. Rathinam et al.   CANCER AND METASTASIS REVIEWS

Hypoxia, inflammation, and the tumor microenvironment in metastatic disease

(2010) Elizabeth C. Finger et al.   CANCER AND METASTASIS REVIEWS

Immunotherapy targeting fibroblast activation protein inhibits tumor growth and increases survival in a murine colon cancer model

(2010) Yuan Wen et al.   CANCER SCIENCE

Hypoxia inducible factor-1 mediates expression of galectin-1: the potential role in migration/invasion of colorectal cancer cells

(2010) Xu-Yun Zhao et al.   CARCINOGENESIS

Targeting Hedgehog -- a Cancer Stem Cell Pathway

(2010) A. A. Merchant et al.   CLINICAL CANCER RESEARCH

CXCL12 (SDF-1)/CXCR4 Pathway in Cancer

(2010) B. A. Teicher et al.   CLINICAL CANCER RESEARCH

Differential gene expression profiling of cultured neu-transformed versus spontaneously-transformed rat cholangiocytes and of corresponding cholangiocarcinomas

(2010) Catherine I. Dumur et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Small molecule c-Met kinase inhibitors: a review of recent patents

(2010) John Porter   EXPERT OPINION ON THERAPEUTIC PATENTS

Preclinical assessment of fibroblast activation protein as a target for antitumor therapy

(2010) Simon W Hayward   Future Oncology

Expression of the extracellular matrix protein periostin in liver tumours and bile duct carcinomas

(2010) Marc-Oliver Riener et al.   HISTOPATHOLOGY

Gene expression profiling of cholangiocarcinoma-derived fibroblast reveals alterations related to tumor progression and indicates periostin as a poor prognostic marker

(2010) Kusumawadee Utispan et al.   Molecular Cancer

Involvement of PI3K and ERK1/2 pathways in hepatocyte growth factor-induced cholangiocarcinoma cell invasion

(2010) Apaporn Menakongka   WORLD JOURNAL OF GASTROENTEROLOGY

Epithelial-Mesenchymal Transition

(2009) Michael W. Klymkowsky et al.   AMERICAN JOURNAL OF PATHOLOGY

Quantitative Analysis of Three-Dimensional Human Mammary Epithelial Tissue Architecture Reveals a Role for Tenascin-C in Regulating c-Met Function

(2009) Agne Taraseviciute et al.   AMERICAN JOURNAL OF PATHOLOGY

Hepatic Stellate Cells May Relate to Progression of Intrahepatic Cholangiocarcinoma

(2009) Hirohisa Okabe et al.   ANNALS OF SURGICAL ONCOLOGY

Discovery of novel sphingosine kinase 1 inhibitors

(2009) Yibin Xiang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Upregulated expression of periostin by hypoxia in non-small-cell lung cancer cells promotes cell survival via the Akt/PKB pathway

(2009) Gaoliang Ouyang et al.   CANCER LETTERS

The multifaceted role of periostin in tumorigenesis

(2009) Kai Ruan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Intrahepatic Cholangiocarcinoma Progression: Prognostic Factors and Basic Mechanisms

(2009) Alphonse E. Sirica et al.   Clinical Gastroenterology and Hepatology

Inhibition of HGF/MET as therapy for malignancy

(2009) Sanjay Naran et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Cancer associated fibroblasts (CAFs) in tumor microenvironment

(2009) Fei Xing   Frontiers in Bioscience-Landmark

The epithelial-mesenchymal transition: Fact or fiction in cancer?

(2009) Gianluigi Giannelli   HEPATOLOGY

Portal fibroblasts: Underappreciated mediators of biliary fibrosis

(2009) Jonathan A. Dranoff et al.   HEPATOLOGY

Epithelial-to-mesenchymal transitions in the liver

(2009) Steve S. Choi et al.   HEPATOLOGY

CD10+ fibroblasts are more involved in the progression of hilar/extrahepatic cholangiocarcinoma than of peripheral intrahepatic cholangiocarcinoma

(2009) Yunosuke Nishihara et al.   HISTOPATHOLOGY

Incorporation of Tenascin-C into the Extracellular Matrix by Periostin Underlies an Extracellular Meshwork Architecture

(2009) Isao Kii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Therapeutic targeting of the PDGF and TGF-β-signaling pathways in hepatic stellate cells by PTK787/ZK22258

(2009) Yuqing Liu et al.   LABORATORY INVESTIGATION

A Comprehensive Analysis of Immunohistochemical Studies in Intrahepatic Cholangiocarcinoma Using the Survival Tree Model

(2009) Tomohiro Iguchi et al.   ONCOLOGY

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

Cancer associated fibroblasts in cancer pathogenesis

(2009) Omar E. Franco et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression

(2009) Masayuki Shimoda et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Molecular biology of cancer-associated fibroblasts: Can these cells be targeted in anti-cancer therapy?

(2009) Tamas A. Gonda et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Targeting SphK1 as a New Strategy against Cancer

(2008) Dai Shida et al.   CURRENT DRUG TARGETS

Galectin-1 Is a Novel Functional Receptor for Tissue Plasminogen Activator in Pancreatic Cancer

(2008) Oriol Roda et al.   GASTROENTEROLOGY

Lymphatic spread is related to VEGF-C expression and D2-40-positive myofibroblasts in intrahepatic cholangiocarcinoma

(2008) Shinichi Aishima et al.   MODERN PATHOLOGY

Stabilization of hepatocyte growth factor mRNA by hypoxia-inducible factor 1

(2008) Sheng-Hua Chu et al.   MOLECULAR BIOLOGY REPORTS