Manganese homeostasis in the nervous system

Pathology of inherited manganese transporter deficiency

(2014) Mirna Lechpammer et al.   ANNALS OF NEUROLOGY

Parkinson's disease-linked human PARK9/ATP13A2 maintains zinc homeostasis and promotes α-Synuclein externalization via exosomes

(2014) Stephanie M.Y. Kong et al.   HUMAN MOLECULAR GENETICS

SLC30A10 Is a Cell Surface-Localized Manganese Efflux Transporter, and Parkinsonism-Causing Mutations Block Its Intracellular Trafficking and Efflux Activity

(2014) D. Leyva-Illades et al.   JOURNAL OF NEUROSCIENCE

Genetic factors and manganese-induced neurotoxicity

(2014) Pan Chen et al.   Frontiers in Genetics

Nonoccupational Environmental Exposure to Manganese is Linked to Deficits in Peripheral and Central Olfactory Function

(2013) M. Guarneros et al.   CHEMICAL SENSES

Manganese-induced parkinsonism in methcathinone abusers: bio-markers of exposure and follow-up

(2013) K. Sikk et al.   EUROPEAN JOURNAL OF NEUROLOGY

Zn2+ dyshomeostasis caused by loss of ATP13A2/PARK9 leads to lysosomal dysfunction and alpha-synuclein accumulation

(2013) Taiji Tsunemi et al.   HUMAN MOLECULAR GENETICS

The SLC30 family of zinc transporters – A review of current understanding of their biological and pathophysiological roles

(2013) Liping Huang et al.   MOLECULAR ASPECTS OF MEDICINE

Mutations in SLC30A10 Cause Parkinsonism and Dystonia with Hypermanganesemia, Polycythemia, and Chronic Liver Disease

(2012) Marialuisa Quadri et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Syndrome of Hepatic Cirrhosis, Dystonia, Polycythemia, and Hypermanganesemia Caused by Mutations in SLC30A10 , a Manganese Transporter in Man

(2012) Karin Tuschl et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Physiologic implications of metal-ion transport by ZIP14 and ZIP8

(2012) Supak Jenkitkasemwong et al.   BIOMETALS

Increased whole blood manganese concentrations observed in children with iron deficiency anaemia

(2012) Elisabeth Anne Smith et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Parkinsonism in cirrhosis: pathogenesis and current therapeutic options

(2012) Roger F. Butterworth   METABOLIC BRAIN DISEASE

Efflux function, tissue-specific expression and intracellular trafficking of the Zn transporter ZnT10 indicate roles in adult Zn homeostasis

(2012) Helen J. Bosomworth et al.   Metallomics

Tremor, olfactory and motor changes in Italian adolescents exposed to historical ferro-manganese emission

(2012) Roberto G. Lucchini et al.   NEUROTOXICOLOGY

Manganese transport via the transferrin mechanism

(2012) Thomas E. Gunter et al.   NEUROTOXICOLOGY

The iron transporter ferroportin can also function as a manganese exporter

(2011) Michael S. Madejczyk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Regulation of Intracellular Manganese Homeostasis by Kufor-Rakeb Syndrome-associated ATP13A2 Protein

(2011) Jieqiong Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association between divalent metal transport 1 encoding gene (SLC11A2) and disease duration in amyotrophic lateral sclerosis

(2011) Hélène Blasco et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Blood manganese levels in patients with hepatic encephalopathy

(2011) Hugo Mendieta Zerón et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

DMT1 polymorphism and risk of Parkinson’s disease

(2011) Qing He et al.   NEUROSCIENCE LETTERS

Iron disorders of genetic origin: a changing world

(2011) Pierre Brissot et al.   TRENDS IN MOLECULAR MEDICINE

Vesicular distribution of Secretory Pathway Ca2+-ATPase isoform 1 and a role in manganese detoxification in liver-derived polarized cells

(2010) Sharon Leitch et al.   BIOMETALS

Induction of FPN1 transcription by MTF-1 reveals a role for ferroportin in transition metal efflux

(2010) M.-B. Troadec et al.   BLOOD

Manganese and Parkinson’s Disease: A Critical Review and New Findings

(2010) Tomás R. Guilarte   ENVIRONMENTAL HEALTH PERSPECTIVES

Manganese-induced Trafficking and Turnover of the cis-Golgi Glycoprotein GPP130

(2010) Somshuvra Mukhopadhyay et al.   MOLECULAR BIOLOGY OF THE CELL

Clinical spectrum of Kufor-Rakeb syndrome in the Chilean kindred with ATP13A2 mutations

(2010) Maria I. Behrens et al.   MOVEMENT DISORDERS

Identification of a gain-of-function mutation in a Golgi P-type ATPase that enhances Mn2+ efflux and protects against toxicity

(2010) S. Mukhopadhyay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Uptake of Materials from the Nasal Cavity into the Blood and Brain

(2009) Mary Beth Genter et al.   Annals of the New York Academy of Sciences

Ferroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulation

(2009) Zhaobao Yin et al.   JOURNAL OF NEUROCHEMISTRY

Parkinson's disease

(2009) Andrew J Lees et al.   LANCET

α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

(2009) Aaron D Gitler et al.   NATURE GENETICS

Structure, mechanism and regulation of pyruvate carboxylase

(2008) Sarawut Jitrapakdee et al.   BIOCHEMICAL JOURNAL

Iron-enhanced paraquat-mediated dopaminergic cell death due to increased oxidative stress as a consequence of microglial activation

(2008) Jun Peng et al.   FREE RADICAL BIOLOGY AND MEDICINE

The overlapping roles of manganese and Cu/Zn SOD in oxidative stress protection

(2008) Amit R. Reddi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hepatic cirrhosis, dystonia, polycythaemia and hypermanganesaemia—A new metabolic disorder

(2008) Karin Tuschl et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Slc39a14 Gene Encodes ZIP14, A Metal/Bicarbonate Symporter: Similarities to the ZIP8 Transporter

(2008) K. Girijashanker et al.   MOLECULAR PHARMACOLOGY

Manganese transport in eukaryotes: The role of DMT1

(2008) Catherine Au et al.   NEUROTOXICOLOGY

Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease

(2008) J. Salazar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of the rat blood-brain barrier choline transporter by manganese chloride

(2003) Paul R. Lockman et al.   JOURNAL OF NEUROCHEMISTRY