Lanthionine ketimine ester provides benefit in a mouse model of multiple sclerosis

Molecular mechanisms linking neuroinflammation and neurodegeneration in MS

(2014) Erik Ellwardt et al.   EXPERIMENTAL NEUROLOGY

Effects of peptide fraction and counter ion on the development of clinical signs in experimental autoimmune encephalomyelitis

(2014) Anne I. Boullerne et al.   JOURNAL OF NEUROCHEMISTRY

The central role of mitochondria in axonal degeneration in multiple sclerosis

(2014) Graham R Campbell et al.   Multiple Sclerosis Journal

CRMP2

(2014) Jacque P.K. Ip et al.   NEUROSCIENTIST

Mitochondrial immobilization mediated by syntaphilin facilitates survival of demyelinated axons

(2014) Nobuhiko Ohno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The functionalized amino acid (S)-Lacosamide subverts CRMP2-mediated tubulin polymerization to prevent constitutive and activity-dependent increase in neurite outgrowth

(2014) Sarah M. Wilson et al.   Frontiers in Cellular Neuroscience

Chemokine receptor expression by inflammatory T cells in EAE

(2014) Jyothi Thyagabhavan Mony et al.   Frontiers in Cellular Neuroscience

Early axonal damage and progressive myelin pathology define the kinetics of CNS histopathology in a mouse model of multiple sclerosis

(2013) Mascha S. Recks et al.   CLINICAL IMMUNOLOGY

A Derivative of the Brain Metabolite Lanthionine Ketimine Improves Cognition and Diminishes Pathology in the 3×Tg-AD Mouse Model of Alzheimer Disease

(2013) Kenneth Hensley et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Lanthionine ketimine ethyl ester partially rescues neurodevelopmental defects inunc-33(DPYSL2/CRMP2) mutants

(2013) Caleb Hubbard et al.   JOURNAL OF NEUROSCIENCE RESEARCH

GEMSP exerts a myelin-protecting role in the rat optic nerve

(2013) Arturo Mangas et al.   NEUROLOGICAL RESEARCH

Limiting multiple sclerosis related axonopathy by blocking Nogo receptor and CRMP-2 phosphorylation

(2012) Steven Petratos et al.   BRAIN

Localized role of CRMP1 and CRMP2 in neurite outgrowth and growth cone steering

(2012) Masakazu Higurashi et al.   Developmental Neurobiology

Mechanisms regulating regional localization of inflammation during CNS autoimmunity

(2012) Emily Pierson et al.   IMMUNOLOGICAL REVIEWS

Human T Lymphotropic Virus Type 1 Increases T Lymphocyte Migration by Recruiting the Cytoskeleton Organizer CRMP2

(2012) M. Varrin-Doyer et al.   JOURNAL OF IMMUNOLOGY

Collapsin response mediator protein-2 phosphorylation promotes the reversible retraction of oligodendrocyte processes in response to non-lethal oxidative stress

(2012) Agata Fernández-Gamba et al.   JOURNAL OF NEUROCHEMISTRY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

A derivative of the CRMP2 binding compound lanthionine ketimine provides neuroprotection in a mouse model of cerebral ischemia

(2012) Shadia E. Nada et al.   NEUROCHEMISTRY INTERNATIONAL

Differential patterns of spinal cord pathology induced by MP4, MOG peptide 35-55, and PLP peptide 178-191 in C57BL/6 mice

(2011) STEFANIE KUERTEN et al.   APMIS

Class 3 semaphorins influence oligodendrocyte precursor recruitment and remyelination in adult central nervous system

(2011) Gabrièle Piaton et al.   BRAIN

Distinct pathological patterns in relapsing–remitting and chronic models of experimental autoimmune enchephalomyelitis and the neuroprotective effect of glatiramer acetate

(2011) Rina Aharoni et al.   JOURNAL OF AUTOIMMUNITY

Collapsin Response Mediator Protein-2: An Emerging Pathologic Feature and Therapeutic Target for Neurodisease Indications

(2011) Kenneth Hensley et al.   MOLECULAR NEUROBIOLOGY

Axon cytoskeleton proteins specifically modulate oligodendrocyte growth and differentiation in vitro

(2011) Catherine Fressinaud et al.   NEUROCHEMISTRY INTERNATIONAL

Spinal cord histopathology of MOG peptide 35–55-induced experimental autoimmune encephalomyelitis is time- and score-dependent

(2011) Mascha S. Recks et al.   NEUROSCIENCE LETTERS

Oestrogen receptor β ligand: a novel treatment to enhance endogenous functional remyelination

(2010) Daniel K. Crawford et al.   BRAIN

Reduced expression of plasma membrane calcium ATPase 2 and collapsin response mediator protein 1 promotes death of spinal cord neurons

(2010) M P Kurnellas et al.   CELL DEATH AND DIFFERENTIATION

The Suppression of CRMP2 Expression by Bone Morphogenetic Protein (BMP)-SMAD Gradient Signaling Controls Multiple Stages of Neuronal Development

(2010) Yiming Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel Therapeutic Targets for Axonal Degeneration in Multiple Sclerosis

(2010) Steven Petratos et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Proteomic Identification of Binding Partners for the Brain Metabolite Lanthionine Ketimine (LK) and Documentation of LK Effects on Microglia and Motoneuron Cell Cultures

(2010) K. Hensley et al.   JOURNAL OF NEUROSCIENCE

Emerging Biological Importance of Central Nervous System Lanthionines

(2010) Kenneth Hensley et al.   MOLECULES

Mechanisms of neuronal dysfunction and degeneration in multiple sclerosis

(2010) Ranjan Dutta et al.   PROGRESS IN NEUROBIOLOGY

Altered expression of CRMPs in the brain of bovine spongiform encephalopathy-infected mice during disease progression

(2009) Nathalie Auvergnon et al.   BRAIN RESEARCH

Increased CRMP2 Phosphorylation is Observed in Alzheimers Disease; Does this Tell us Anything About Disease Development?

(2009) M. Soutar et al.   Current Alzheimer Research

Phosphorylation of Collapsin Response Mediator Protein 2 on Tyr-479 Regulates CXCL12-induced T Lymphocyte Migration

(2009) Michel Varrin-Doyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CaMKII phosphorylates collapsin response mediator protein 2 and modulates axonal damage during glutamate excitotoxicity

(2009) Sheng T. Hou et al.   JOURNAL OF NEUROCHEMISTRY

Processing and Nuclear Localization of CRMP2 during Brain Development Induce Neurite Outgrowth Inhibition

(2008) Véronique Rogemond et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High CRMP2 expression in peripheral T lymphocytes is associated with recruitment to the brain during virus-induced neuroinflammation

(2007) C. Vuaillat et al.   JOURNAL OF NEUROIMMUNOLOGY