The central role of mitochondria in axonal degeneration in multiple sclerosis

Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models

(2014) Cornelia Schuh et al.   ACTA NEUROPATHOLOGICA

Multiple sclerosis: Prospects and promise

(2013) Stephen L. Hauser et al.   ANNALS OF NEUROLOGY

Mitochondrial genome changes and neurodegenerative diseases

(2013) Milena Pinto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Myelin Loss Does Not Lead to Axonal Degeneration in a Long-Lived Model of Chronic Demyelination

(2013) C. M. Smith et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial dysfunction contributes to neurodegeneration in multiple sclerosis

(2013) Maarten E. Witte et al.   TRENDS IN MOLECULAR MEDICINE

Clonally expanded mitochondrial DNA deletions within the choroid plexus in multiple sclerosis

(2012) Graham R. Campbell et al.   ACTA NEUROPATHOLOGICA

Reduced expression of PGC-1α partly underlies mitochondrial changes and correlates with neuronal loss in multiple sclerosis cortex

(2012) Maarten E. Witte et al.   ACTA NEUROPATHOLOGICA

NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

(2012) Marie T. Fischer et al.   BRAIN

Metabolic injury to axons and myelin

(2012) Shigeki Tsutsui et al.   EXPERIMENTAL NEUROLOGY

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

Mitochondria as a central sensor for axonal degenerative stimuli

(2012) Felipe A. Court et al.   TRENDS IN NEUROSCIENCES

Analysis of the mitochondrial proteome in multiple sclerosis cortex

(2011) Laurie Broadwater et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis

(2011) Jessica L. Zambonin et al.   BRAIN

Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis

(2011) Owain W. Howell et al.   BRAIN

Myelination and Axonal Electrical Activity Modulate the Distribution and Motility of Mitochondria at CNS Nodes of Ranvier

(2011) N. Ohno et al.   JOURNAL OF NEUROSCIENCE

A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis

(2011) Ivana Nikić et al.   NATURE MEDICINE

Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo

(2011) F. H. Sterky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis

(2010) Graham R. Campbell et al.   ANNALS OF NEUROLOGY

A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis

(2010) Roberta Magliozzi et al.   ANNALS OF NEUROLOGY

Somatic Mitochondrial DNA Mutations in Mammalian Aging

(2010) Nils-Göran Larsson   Annual Review of Biochemistry

Inflammation, demyelination, and degeneration — Recent insights from MS pathology

(2010) Christine Stadelmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Demyelination and axonal preservation in a transgenic mouse model of Pelizaeus-Merzbacher disease

(2010) Julia M. Edgar et al.   EMBO Molecular Medicine

Demyelination Increases Axonal Stationary Mitochondrial Size and the Speed of Axonal Mitochondrial Transport

(2010) S. Kiryu-Seo et al.   JOURNAL OF NEUROSCIENCE

Multiple sclerosis: Distribution of inflammatory cells in newly forming lesions

(2009) Andrew P. D. Henderson et al.   ANNALS OF NEUROLOGY

Mitochondrial changes within axons in multiple sclerosis

(2009) D. J. Mahad et al.   BRAIN

HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage

(2009) Jin Young Kim et al.   NATURE NEUROSCIENCE

Control of mitochondrial transport and localization in neurons

(2009) Andrew F. MacAskill et al.   TRENDS IN CELL BIOLOGY

Gray matter atrophy in multiple sclerosis: A longitudinal study

(2008) Elizabeth Fisher et al.   ANNALS OF NEUROLOGY

Mitochondrial defects in acute multiple sclerosis lesions

(2008) Don Mahad et al.   BRAIN

Docking of Axonal Mitochondria by Syntaphilin Controls Their Mobility and Affects Short-Term Facilitation

(2008) Jian-Sheng Kang et al.   CELL

Increase in mitochondrial density within axons and supporting cells in response to demyelination in thePlp1mouse model

(2008) Vanessa Hogan et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET

Resistance is futile: antineuronal autoimmunity in multiple sclerosis

(2008) Ruth Huizinga et al.   TRENDS IN IMMUNOLOGY