Mechanism of the ABC transporter ATPase domains: catalytic models and the biochemical and biophysical record

Time-resolved Fourier Transform Infrared Spectroscopy of the Nucleotide-binding Domain from the ATP-binding Cassette Transporter MsbA

(2012) Falk Syberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of the D-Loops in Allosteric Control of ATP Hydrolysis in an ABC Transporter

(2012) Peter M. Jones et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Missing Fragments: Detecting Cooperative Binding in Fragment-Based Drug Design

(2012) Pramod C. Nair et al.   ACS Medicinal Chemistry Letters

Conformational Coupling of the Nucleotide-Binding and the Transmembrane Domains in ABC Transporters

(2011) Po-Chao Wen et al.   BIOPHYSICAL JOURNAL

Extent of Nucleotide-Binding Domain (NBD) Separation When a CFTR Channel Closes

(2011) Luiz Artur et al.   BIOPHYSICAL JOURNAL

Molecular-Dynamics Simulations of the ATP/apo State of a Multidrug ATP-Binding Cassette Transporter Provide a Structural and Mechanistic Basis for the Asymmetric Occluded State

(2011) Peter M. Jones et al.   BIOPHYSICAL JOURNAL

Kinetics of the Association/Dissociation Cycle of an ATP-binding Cassette Nucleotide-binding Domain

(2011) Maria E. Zoghbi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P-glycoprotein Retains Drug-stimulated ATPase Activity upon Covalent Linkage of the Two Nucleotide Binding Domains at Their C-terminal Ends

(2011) Brandy Verhalen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic Ligand-induced Conformational Rearrangements in P-glycoprotein as Probed by Fluorescence Resonance Energy Transfer Spectroscopy

(2011) Brandy Verhalen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutant cycles at CFTR’s non-canonical ATP-binding site support little interface separation during gating

(2011) Andras Szollosi et al.   JOURNAL OF GENERAL PHYSIOLOGY

Dimerization of ABCG2 Analysed by Bimolecular Fluorescence Complementation

(2011) Ameena J. Haider et al.   PLoS One

Crystal Structure of the Maltose Transporter in a Pretranslocation Intermediate State

(2011) M. L. Oldham et al.   SCIENCE

Human P-glycoprotein is active when the two halves are clamped together in the closed conformation

(2010) Tip W. Loo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lipid Composition Regulates the Orientation of Transmembrane Helices in HorA, an ABC Multidrug Transporter

(2010) Adelin Gustot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of an Asymmetric Occluded State of P-glycoprotein with Two Bound Nucleotides

(2010) Alena Siarheyeva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Challenges in the determination of the binding modes of non-standard ligands in X-ray crystal complexes

(2010) Alpeshkumar K. Malde et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Stable ATP binding mediated by a partial NBD dimer of the CFTR chloride channel

(2010) Ming-Feng Tsai et al.   JOURNAL OF GENERAL PHYSIOLOGY

The maltose ATP-binding cassette transporter in the 21st century - towards a structural dynamic perspective on its mode of action

(2010) Enrica Bordignon et al.   MOLECULAR MICROBIOLOGY

Dynamics of  -helical subdomain rotation in the intact maltose ATP-binding cassette transporter

(2010) C. Orelle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ATP-binding cassette family: a structural perspective

(2009) Veronica Kos et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

ABC Efflux Pump-Based Resistance to Chemotherapy Drugs

(2009) Paul D. W. Eckford et al.   CHEMICAL REVIEWS

Multidrug efflux pumps: The structures of prokaryotic ATP-binding cassette transporter efflux pumps and implications for our understanding of eukaryotic P-glycoproteins and homologues

(2009) Ian D. Kerr et al.   FEBS Journal

Multidrug efflux pumps: Substrate selection in ATP-binding cassette multidrug efflux pumps - first come, first served?

(2009) Robert Ernst et al.   FEBS Journal

Transmembrane Signaling in the Maltose ABC Transporter MalFGK2-E

(2009) Mathias Grote et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

State-dependent modulation of CFTR gating by pyrophosphate

(2009) Ming-Feng Tsai et al.   JOURNAL OF GENERAL PHYSIOLOGY

Conformational Cycle of the ABC Transporter MsbA in Liposomes: Detailed Analysis Using Double Electron–Electron Resonance Spectroscopy

(2009) Ping Zou et al.   JOURNAL OF MOLECULAR BIOLOGY

Alternating Access of the Putative Substrate-Binding Chamber in the ABC Transporter MsbA

(2009) Ping Zou et al.   JOURNAL OF MOLECULAR BIOLOGY

Alternating Access in Maltose Transporter Mediated by Rigid-Body Rotations

(2009) Dheeraj Khare et al.   MOLECULAR CELL

Structural arrangement of the transmission interface in the antigen ABC transport complex TAP

(2009) G. Oancea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE

ABC transporters: a riddle wrapped in a mystery inside an enigma

(2009) Peter M. Jones et al.   TRENDS IN BIOCHEMICAL SCIENCES

Monitoring conformational changes during the catalytic cycle of OpuAA, the ATPase subunit of the ABC transporter OpuA fromBacillus subtilis

(2008) Carsten Horn et al.   BIOCHEMICAL JOURNAL

Mg2+-dependent ATP occlusion at the first nucleotide-binding domain (NBD1) of CFTR does not require the second (NBD2)

(2008) Luba Aleksandrov et al.   BIOCHEMICAL JOURNAL

A Comparative Electron Paramagnetic Resonance Study of the Nucleotide-Binding Domains’ Catalytic Cycle in the Assembled Maltose ATP-Binding Cassette Importer

(2008) Mathias Grote et al.   BIOPHYSICAL JOURNAL

Structure, Function, and Evolution of Bacterial ATP-Binding Cassette Systems

(2008) A. L. Davidson et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Opening of the ADP-bound active site in the ABC transporter ATPase dimer: Evidence for a constant contact, alternating sites model for the catalytic cycle

(2008) Peter M. Jones et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

The High-Affinity E. coli Methionine ABC Transporter: Structure and Allosteric Regulation

(2008) N. S. Kadaba et al.   SCIENCE