A role for the Ca2+-dependent tyrosine kinase Pyk2 in tonic depolarization-induced vascular smooth muscle contraction

A Role for the Tyrosine Kinase Pyk2 in Depolarization-induced Contraction of Vascular Smooth Muscle

(2015) Ryan D. Mills et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reconstituted Human Myosin Light Chain Phosphatase Reveals Distinct Roles of Two Inhibitory Phosphorylation Sites of the Regulatory Subunit, MYPT1

(2014) Mukta Khasnis et al.   BIOCHEMISTRY

In vivoroles for myosin phosphatase targeting subunit-1 phosphorylation sites T694 and T852 in bladder smooth muscle contraction

(2014) Cai-Ping Chen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Role of the essential light chain in the activation of smooth muscle myosin by regulatory light chain phosphorylation

(2013) Kenneth A. Taylor et al.   JOURNAL OF STRUCTURAL BIOLOGY

Myosin Regulatory Light Chain Diphosphorylation Slows Relaxation of Arterial Smooth Muscle

(2012) Cindy Sutherland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Actin Filament Dynamics in the Myogenic Response of Cerebral Resistance Arteries

(2012) Michael P Walsh et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Size-dependent heterogeneity of contractile Ca2+sensitization in rat arterial smooth muscle

(2012) Toshio Kitazawa et al.   JOURNAL OF PHYSIOLOGY-LONDON

Biochemistry of smooth muscle myosin light chain kinase

(2011) Feng Hong et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The importance of Rho-associated kinase-induced Ca2+ sensitization as a component of electromechanical and pharmacomechanical coupling in rat ureteric smooth muscle

(2011) Lyudmyla Borysova et al.   CELL CALCIUM

Phosphorylated Smooth Muscle Heavy Meromyosin Shows an Open Conformation Linked to Activation

(2011) Bruce A.J. Baumann et al.   JOURNAL OF MOLECULAR BIOLOGY

Modular Structure of Smooth Muscle Myosin Light Chain Kinase: Hydrodynamic Modeling and Functional Implications

(2010) Yasuko Mabuchi et al.   BIOCHEMISTRY

PYK2/PDZ-RhoGEF Links Ca 2+ Signaling to RhoA

(2009) Zhekang Ying et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Salicylates dilate blood vessels through inhibiting PYK2-mediated RhoA/Rho-kinase activation

(2009) Zhekang Ying et al.   CARDIOVASCULAR RESEARCH

Calcium-independent phospholipase A2 participates in KCl-induced calcium sensitization of vascular smooth muscle

(2009) Paul H. Ratz et al.   CELL CALCIUM

Targeting Pyk2 for therapeutic intervention

(2009) Christopher A Lipinski et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Structural Characterization of Proline-rich Tyrosine Kinase 2 (PYK2) Reveals a Unique (DFG-out) Conformation and Enables Inhibitor Design

(2009) Seungil Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Actin cytoskeletal dynamics in smooth muscle: a new paradigm for the regulation of smooth muscle contraction

(2008) Susan J. Gunst et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Protein-tyrosine kinase CAKβ/PYK2 is activated by binding Ca2+/calmodulin to FERM F2 α2 helix and thus forming its dimer

(2008) Takayuki Kohno et al.   BIOCHEMICAL JOURNAL

Isoflavone Attenuates Vascular Contraction through Inhibition of the RhoA/Rho-Kinase Signaling Pathway

(2008) Y. M. Seok et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS