More Than a Pore: The Interplay of Pore-Forming Proteins and Lipid Membranes

Membrane curvature modulation of protein activity determined by NMR

(2015) Richard M. Epand et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cholesterol stimulates and ceramide inhibits Sticholysin II-induced pore formation in complex bilayer membranes

(2015) Ida Alm et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Structural basis for self-assembly of a cytolytic pore lined by protein and lipid

(2015) Koji Tanaka et al.   Nature Communications

The role of spontaneous lipid curvature in the interaction of interfacially active peptides with membranes

(2014) Daniel Koller et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Sticholysin I–membrane interaction: An interplay between the presence of sphingomyelin and membrane fluidity

(2014) Lohans Pedrera et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Protein Arcs May Form Stable Pores in Lipid Membranes

(2014) Lidia Prieto et al.   BIOPHYSICAL JOURNAL

Perforin oligomers form arcs in cellular membranes: a locus for intracellular delivery of granzymes

(2014) S S Metkar et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial alterations in apoptosis

(2014) Katia Cosentino et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Toxicity of an α-Pore-forming Toxin Depends on the Assembly Mechanism on the Target Membrane as Revealed by Single Molecule Imaging

(2014) Yamunadevi Subburaj et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Model of Active Bax at the Membrane

(2014) Stephanie Bleicken et al.   MOLECULAR CELL

Membrane pore formation at protein–lipid interfaces

(2014) Robert J.C. Gilbert et al.   TRENDS IN BIOCHEMICAL SCIENCES

Incomplete pneumolysin oligomers form membrane pores

(2014) A. F.- P. Sonnen et al.   Open Biology

The sticholysin family of pore-forming toxins induces the mixing of lipids in membrane domains

(2013) Uris Ros et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cardiolipin Effects on Membrane Structure and Dynamics

(2013) Joseph D. Unsay et al.   LANGMUIR

Three-dimensional structure of Bax-mediated pores in membrane bilayers

(2013) X-P Xu et al.   Cell Death & Disease

The secrets of the Bcl-2 family

(2012) A J García-Sáez   CELL DEATH AND DIFFERENTIATION

Pathogenic Pore-Forming Proteins: Function and Host Response

(2012) Mirko Bischofberger et al.   Cell Host & Microbe

Mechanisms for the Insertion of Toxic, Fibril-like β-Amyloid Oligomers into the Membrane

(2012) Hyunbum Jang et al.   Journal of Chemical Theory and Computation

The behavior of sea anemone actinoporins at the water–membrane interface

(2011) Lucía García-Ortega et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Membrane assembly of the cholesterol-dependent cytolysin pore complex

(2011) Eileen M. Hotze et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Structural Dynamics of a Lytic Peptide Interacting with a Supported Lipid Bilayer

(2011) Andrew C. Rapson et al.   BIOPHYSICAL JOURNAL

A lipocentric view of peptide-induced pores

(2011) Gustavo Fuertes et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Oligomerization and Pore Formation by Equinatoxin II Inhibit Endocytosis and Lead to Plasma Membrane Reorganization

(2011) Ana J. García-Sáez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Insights into the Oligomerization and Architecture of Eukaryotic Membrane Pore-Forming Toxins

(2011) Ariel E. Mechaly et al.   STRUCTURE

Structure and assembly of pore-forming proteins

(2010) Ioan Iacovache et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface

(2010) A. J. Farrand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cholesterol Exposure at the Membrane Surface Is Necessary and Sufficient to Trigger Perfringolysin O Binding

(2009) John J. Flanagan et al.   BIOCHEMISTRY

Induction of non-lamellar lipid phases by antimicrobial peptides: a potential link to mode of action

(2009) Evan F. Haney et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Molecular Interactions between Magainin 2 and Model Membranes in Situ

(2009) Khoi Tan Nguyen et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Piercing insights

(2009) Hagan Bayley   NATURE

The structure of a cytolytic α-helical toxin pore reveals its assembly mechanism

(2009) Marcus Mueller et al.   NATURE

Sea anemone cytolysins as toxic components of immunotoxins

(2009) Mayra Tejuca et al.   TOXICON

Molecular mechanism of pore formation by actinoporins

(2009) Katarina Črnigoj Kristan et al.   TOXICON

Sticholysins, two pore-forming toxins produced by the Caribbean Sea anemone Stichodactyla helianthus: Their interaction with membranes

(2009) Carlos Álvarez et al.   TOXICON

Relationships between the orientation and the structural properties of peptides and their membrane interactions

(2008) L. Lins et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Pore formation: An ancient yet complex form of attack

(2008) Ioan Iacovache et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Equinatoxin II Permeabilizing Activity Depends on the Presence of Sphingomyelin and Lipid Phase Coexistence

(2008) Peter Schön et al.   BIOPHYSICAL JOURNAL

Contributions to Bax insertion and oligomerization of lipids of the mitochondrial outer membrane

(2008) S Lucken-Ardjomande et al.   CELL DEATH AND DIFFERENTIATION

Cardiolipin provides an essential activating platform for caspase-8 on mitochondria

(2008) Francois Gonzalvez et al.   JOURNAL OF CELL BIOLOGY

Structure of transmembrane pore induced by Bax-derived peptide: Evidence for lipidic pores

(2008) S. Qian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disparate proteins use similar architectures to damage membranes

(2008) Gregor Anderluh et al.   TRENDS IN BIOCHEMICAL SCIENCES