Inhibition of the angiotensin-converting enzyme decreases skeletal muscle fibrosis in dystrophic mice by a diminution in the expression and activity of connective tissue growth factor (CTGF/CCN-2)

Angiotensin II: Role in Skeletal Muscle Atrophy

(2012) Claudio Cabello-Verrugio et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Angiotensin II-induced pro-fibrotic effects require p38MAPK activity and transforming growth factor beta 1 expression in skeletal muscle cells

(2012) María Gabriela Morales et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Fibrotic response induced by angiotensin-II requires NAD(P)H oxidase-induced reactive oxygen species (ROS) in skeletal muscle cells

(2011) Claudio Cabello-Verrugio et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regeneration versus fibrosis in skeletal muscle

(2011) Adam L. Moyer et al.   CURRENT OPINION IN RHEUMATOLOGY

Angiotensin II receptor type 1 blockade decreases CTGF/CCN2-mediated damage and fibrosis in normal and dystrophic skeletal muscles

(2011) Claudio Cabello-Verrugio et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

CTGF/CCN-2 over-expression can directly induce features of skeletal muscle dystrophy

(2011) María Gabriela Morales et al.   JOURNAL OF PATHOLOGY

Enalapril treatment discloses an early role of angiotensin II in inflammation- and oxidative stress-related muscle damage in dystrophic mdx mice

(2011) Anna Cozzoli et al.   PHARMACOLOGICAL RESEARCH

Chronic Losartan Administration Reduces Mortality and Preserves Cardiac but Not Skeletal Muscle Function in Dystrophic Mice

(2011) Lawrence T. Bish et al.   PLoS One

Mechanisms of muscle weakness in muscular dystrophy: Figure 1.

(2010) Jeffery A. Goldstein et al.   JOURNAL OF GENERAL PHYSIOLOGY

Targeting Fibrosis in Duchenne Muscular Dystrophy

(2010) Lan Zhou et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Excessive collagen accumulation in dystrophic (mdx) respiratory musculature is independent of enhanced activation of the NF-κB pathway

(2010) K.M. Graham et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Skeletal Muscle NADPH Oxidase Is Increased and Triggers Stretch-Induced Damage in the mdx Mouse

(2010) Nicholas P. Whitehead et al.   PLoS One

TGF-β and fibrosis in different organs — molecular pathway imprints

(2009) Dirk Pohlers et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Contrasting effects of steroids and angiotensin-converting-enzyme inhibitors in a mouse model of dystrophin-deficient cardiomyopathy

(2009) Ralf Bauer et al.   EUROPEAN JOURNAL OF HEART FAILURE

Devil and angel in the renin–angiotensin system: ACE–angiotensin II–AT1 receptor axis vs. ACE2–angiotensin-(1–7)–Mas receptor axis

(2009) Masaru Iwai et al.   HYPERTENSION RESEARCH

Multiple pathological events in exercised dystrophic mdx mice are targeted by pentoxifylline: outcome of a large array of in vivo and ex vivo tests

(2009) Rosa Burdi et al.   JOURNAL OF APPLIED PHYSIOLOGY

Imatinib mesylate ameliorates the dystrophic phenotype in exercised mdx mice

(2009) João Carlos da Silva Bizario et al.   JOURNAL OF NEUROIMMUNOLOGY

Intramuscular renin–angiotensin system is activated in human muscular dystrophy

(2009) Guilian Sun et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Renin-angiotensin system in the pathogenesis of liver fibrosis

(2009) Regina Maria Pereira et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Oxidative stress as a therapeutic target during muscle wasting: considering the complex interactions

(2008) Peter G Arthur et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Adaptive and nonadaptive responses to voluntary wheel running bymdxmice

(2008) Rachel M. Landisch et al.   MUSCLE & NERVE

Gentamicin treatment in exercised mdx mice: Identification of dystrophin-sensitive pathways and evaluation of efficacy in work-loaded dystrophic muscle

(2008) Annamaria De Luca et al.   NEUROBIOLOGY OF DISEASE

Connective tissue growth factor: growth factor, matricellular organizer, fibrotic biomarker or molecular target for anti-fibrotic therapy in SSc?

(2008) D. Abraham   RHEUMATOLOGY

Keeping Pace with ACE

(2008) Pei Wang et al.   SPORTS MEDICINE

Angiotensin II-induced skeletal muscle insulin resistance mediated by NF-κB activation via NADPH oxidase

(2007) Yongzhong Wei et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Skeletal muscle cells express the profibrotic cytokine connective tissue growth factor (CTGF/CCN2), which induces their dedifferentiation

(2007) Cecilia Vial et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Connective tissue growth factor is overexpressed in muscles of human muscular dystrophy

(2007) Guilian Sun et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES