Role of Toll-like receptors in diabetic nephropathy

Cutting Edge: TLR2 Is a Functional Receptor for Acute-Phase Serum Amyloid A

(2014) N. Cheng et al.   JOURNAL OF IMMUNOLOGY

Expression of Toll-Like Receptor 4 in Glomerular Endothelial Cells under Diabetic Conditions

(2013) Shunsuke Takata et al.   ACTA HISTOCHEMICA ET CYTOCHEMICA

Renal Protective Effects of Toll-like Receptor 4 Signaling Blockade in Type 2 Diabetic Mice

(2013) J. J. Cha et al.   ENDOCRINOLOGY

AGE-LDL Activates Toll Like Receptor 4 Pathway and Promotes Inflammatory Cytokines Production in Renal Tubular Epithelial Cells

(2013) Ao Cheng et al.   International Journal of Biological Sciences

Effect of Eritoran, an Antagonist of MD2-TLR4, on Mortality in Patients With Severe Sepsis

(2013) Steven M. Opal et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The TLR4 antagonist CRX-526 protects against advanced diabetic nephropathy

(2013) Miao Lin et al.   KIDNEY INTERNATIONAL

Diabetic nephropathy: the role of inflammation in fibroblast activation and kidney fibrosis

(2013) Keizo Kanasaki et al.   Frontiers in Endocrinology

Inflammation and the pathogenesis of diabetic nephropathy

(2012) Jun Wada et al.   CLINICAL SCIENCE

RAAS Inhibition and Renal Protection

(2012) Leoncini Giovanna et al.   CURRENT PHARMACEUTICAL DESIGN

Spironolactone diminishes urinary albumin excretion in patients with type 1 diabetes and microalbuminuria: a randomized placebo-controlled crossover study

(2012) S. E. Nielsen et al.   DIABETIC MEDICINE

Exacerbation of diabetic nephropathy by hyperlipidaemia is mediated by Toll-like receptor 4 in mice

(2012) T. Kuwabara et al.   DIABETOLOGIA

PAMPs and DAMPs: signal 0s that spur autophagy and immunity

(2012) Daolin Tang et al.   IMMUNOLOGICAL REVIEWS

Serum amyloid A and C-reactive protein levels may predict microalbuminuria and macroalbuminuria in newly diagnosed type 1 diabetic patients

(2012) Anne Julie Overgaard et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Cardiorenal End Points in a Trial of Aliskiren for Type 2 Diabetes

(2012) Hans-Henrik Parving et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Role of High-Mobility Group Box-1 Protein in the Development of Diabetic Nephropathy

(2011) Junghyun Kim et al.   AMERICAN JOURNAL OF NEPHROLOGY

Renal Accumulation of Biglycan and Lipid Retention Accelerates Diabetic Nephropathy

(2011) Joel Thompson et al.   AMERICAN JOURNAL OF PATHOLOGY

Knockout of Toll-Like Receptor-2 Attenuates Both the Proinflammatory State of Diabetes and Incipient Diabetic Nephropathy

(2011) Sridevi Devaraj et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of Toll-like receptors in liver health and disease

(2011) Ruth Broering et al.   CLINICAL SCIENCE

HMGB1, TLR and RAGE: a functional tripod that leads to diabetic inflammation

(2011) José Augusto Nogueira-Machado et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Inhibition of TLR2 promotes graft function in a murine model of renal transplant ischemia-reperfusion injury

(2011) Conrad A. Farrar et al.   FASEB JOURNAL

Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid–induced ceramide biosynthesis in mice

(2011) William L. Holland et al.   JOURNAL OF CLINICAL INVESTIGATION

Toll-like Receptor 4 Mediates Oxidized LDL-Induced Macrophage Differentiation to Foam Cells

(2011) Kenneth W. Howell et al.   JOURNAL OF SURGICAL RESEARCH

Toll-Like Receptor 4 Promotes Tubular Inflammation in Diabetic Nephropathy

(2011) M. Lin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy

(2011) Juan F. Navarro-González et al.   Nature Reviews Nephrology

In Vivo Toll-Like Receptor 4 Antagonism Restores Cardiac Function During Endotoxemia

(2011) Stefan Ehrentraut et al.   SHOCK

Increased Expression of Toll-Like Receptor 2 in Rat Diabetic Nephropathy

(2010) Fanglin Li et al.   AMERICAN JOURNAL OF NEPHROLOGY

Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors

(2010) Mohan R. Dasu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis*

(2010) Todd W. Rice et al.   CRITICAL CARE MEDICINE

Increased Toll-Like Receptor (TLR) Activation and TLR Ligands in Recently Diagnosed Type 2 Diabetic Subjects

(2010) M. R. Dasu et al.   DIABETES CARE

Advanced glycation end products-induced apoptosis attenuated by PPARδ activation and epigallocatechin gallate through NF-κB pathway in human embryonic kidney cells and human mesangial cells

(2010) Yao-Jen Liang et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Intracellular Toll-like Receptors

(2010) Amanda L. Blasius et al.   IMMUNITY

Endogenous ligands of TLR2 and TLR4: agonists or assistants?

(2010) Clett Erridge   JOURNAL OF LEUKOCYTE BIOLOGY

HMGB1 Contributes to Kidney Ischemia Reperfusion Injury

(2010) H. Wu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Serum Oxidized-LDL is Associated with Diabetes Duration Independent of Maintaining Optimized Levels of LDL-Cholesterol

(2010) Manouchehr Nakhjavani et al.   LIPIDS

TAK-242 (Resatorvid), a Small-Molecule Inhibitor of Toll-Like Receptor (TLR) 4 Signaling, Binds Selectively to TLR4 and Interferes with Interactions between TLR4 and Its Adaptor Molecules

(2010) N. Matsunaga et al.   MOLECULAR PHARMACOLOGY

Toll-like receptors 2 and 4 in renal ischemia/reperfusion injury

(2010) Krisztina Rusai et al.   PEDIATRIC NEPHROLOGY

Tempering the wrath of RAGE: An emerging therapeutic strategy against diabetic complications, neurodegeneration, and inflammation

(2009) Shi Fang Yan et al.   ANNALS OF MEDICINE

Responses to Amyloids of Microbial and Host Origin Are Mediated through Toll-like Receptor 2

(2009) Çagla Tükel et al.   Cell Host & Microbe

Angiotensin II Induces Inflammatory Response Partly Via Toll-Like Receptor 4-Dependent Signaling Pathway in Vascular Smooth Muscle Cells

(2009) Yuanyuan Ji et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The Role of Toll-Like Receptor Pathways in the Mechanism of Type 1 Diabetes

(2009) Egil Lien et al.   CURRENT MOLECULAR MEDICINE

Toll-like receptors in kidney disease

(2009) Kelly D Smith   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Increased levels of ligands of Toll-like receptors 2 and 4 in type 1 diabetes

(2009) S. Devaraj et al.   DIABETOLOGIA

CXCL16 and oxLDL are induced in the onset of diabetic nephropathy

(2009) Paul Gutwein et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis

(2009) Tatsukata Kawagoe et al.   NATURE IMMUNOLOGY

Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy

(2009) R. Lennon et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Toll-Like Receptors and Renal Disease

(2009) Michael G. Robson   NEPHRON EXPERIMENTAL NEPHROLOGY

How Location Governs Toll-Like Receptor Signaling

(2009) Akanksha Chaturvedi et al.   TRAFFIC

Advanced Glycation End-Product of Low Density Lipoprotein Activates the Toll-Like 4 Receptor Pathway Implications for Diabetic Atherosclerosis

(2008) Conrad P. Hodgkinson et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

(2008) Yumiko Imai et al.   CELL

Toll-like receptor polymorphisms and susceptibility to human disease

(2008) E. Ann Misch et al.   CLINICAL SCIENCE

Telmisartan, ramipril, or both in patients at high risk for vascular events

(2008) Donald G. Vidt   CURRENT HYPERTENSION REPORTS

Role of AGEs in Diabetic Nephropathy

(2008) Kei Fukami et al.   CURRENT PHARMACEUTICAL DESIGN

The activation of NF-κB and AP-1 in peripheral blood mononuclear cells isolated from patients with diabetic nephropathy

(2008) Ji Sun Nam et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

In vitro inhibition of enterobacteria-reactive CD4+CD25− T cells and suppression of immunoinflammatory colitis in mice by the novel immunomodulatory agent VGX-1027

(2008) Katia Mangano et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

TLR4 Links Podocytes with the Innate Immune System to Mediate Glomerular Injury

(2008) M. C. Banas et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Telmisartan, Ramipril, or Both in Patients at High Risk for Vascular Events

(2008)   NEW ENGLAND JOURNAL OF MEDICINE