Role of Toll-like receptors in liver health and disease

Corticosteroids shift the Toll-like receptor response pattern of primary-isolated murine liver cells from an inflammatory to an anti-inflammatory state

(2011) R. Broering et al.   INTERNATIONAL IMMUNOLOGY

The interferon stimulated gene 15 functions as a proviral factor for the hepatitis C virus and as a regulator of the IFN response

(2010) R. Broering et al.   GUT

Hepatic Expression Patterns of Inflammatory and Immune Response Genes Associated with Obesity and NASH in Morbidly Obese Patients

(2010) Adeline Bertola et al.   PLoS One

NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis

(2010) Shin Maeda   Gastroenterology Research and Practice

Toll-Like Receptors in the Pathogenesis of Alcoholic Liver Disease

(2010) Jan Petrasek et al.   Gastroenterology Research and Practice

Lipopolysaccharide-induced innate immune responses in primary hepatocytes downregulates woodchuck hepatitis virus replication via interferon-independent pathways

(2009) Xiaoyong Zhang et al.   CELLULAR MICROBIOLOGY

Not interferon, but interleukin-6 controls early gene expression in hepatitis B virus infection

(2009) Marianna Hösel et al.   HEPATOLOGY

Impaired expression and function of toll-like receptor 7 in hepatitis C virus infection in human hepatoma cells

(2009) Serena Chang et al.   HEPATOLOGY

Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific

(2009) Jun Wu et al.   IMMUNOLOGY

Toll-like receptors and their role in gastrointestinal disease

(2009) Adam G Testro et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

ISG15, a ubiquitin-like interferon-stimulated gene, promotes hepatitis C virus production in vitro: implications for chronic infection and response to treatment

(2009) L. Chen et al.   JOURNAL OF GENERAL VIROLOGY

Toll-like receptor activated human and murine hepatic stellate cells are potent regulators of hepatitis C virus replication

(2009) Bo Wang et al.   JOURNAL OF HEPATOLOGY

Toll-Like Receptor 3 Mediates Establishment of an Antiviral State against Hepatitis C Virus in Hepatoma Cells

(2009) N. Wang et al.   JOURNAL OF VIROLOGY

The kinase activities of interleukin-1 receptor associated kinase (IRAK)-1 and 4 are redundant in the control of inflammatory cytokine expression in human cells

(2009) Kyung W. Song et al.   MOLECULAR IMMUNOLOGY

Disruption of TAK1 in hepatocytes causes hepatic injury, inflammation, fibrosis, and carcinogenesis

(2009) S. Inokuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TAK-242 selectively suppresses Toll-like receptor 4-signaling mediated by the intracellular domain

(2008) Tomohiro Kawamoto et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A molecular link between inflammation and fibrogenesis: The bacterial microflora influences hepatic fibrosis via toll-like receptor 4-dependent modification of transforming growth factor-β signaling in hepatic stellate cells

(2008) Tom Luedde et al.   HEPATOLOGY

The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88

(2008) Istvan Hritz et al.   HEPATOLOGY

Hepatitis B virus suppresses toll-like receptor-mediated innate immune responses in murine parenchymal and nonparenchymal liver cells

(2008) Jun Wu et al.   HEPATOLOGY

TLRs antiviral effect on hepatitis B virus in HepG2 cells

(2008) C. Xia et al.   JOURNAL OF APPLIED MICROBIOLOGY

Toll-like receptor-stimulated non-parenchymal liver cells can regulate hepatitis C virus replication

(2008) Ruth Broering et al.   JOURNAL OF HEPATOLOGY

Characterization of the innate immune signalling pathways in hepatocyte cell lines

(2008) S. Preiss et al.   JOURNAL OF VIRAL HEPATITIS

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

(2008) Akin Akinc et al.   NATURE BIOTECHNOLOGY