A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis*

Clinical impact of a commercially available multiplex PCR system for rapid detection of pathogens in patients with presumed sepsis

(2009) Christine Dierkes et al.   BMC INFECTIOUS DISEASES

Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model

(2009) K Takashima et al.   BRITISH JOURNAL OF PHARMACOLOGY

Multiplex real-time PCR and blood culture for identification of bloodstream pathogens in patients with suspected sepsis

(2009) H. Westh et al.   CLINICAL MICROBIOLOGY AND INFECTION

The Web in the management of biomarkers of sepsis

(2009) John C. Marshall et al.   CRITICAL CARE MEDICINE

Toll-like receptors 4 contribute to endothelial injury and inflammation in hemorrhagic shock in mice

(2009) Ygal Benhamou et al.   CRITICAL CARE MEDICINE

Lung Inflammation Induced by Lipoteichoic Acid or Lipopolysaccharide in Humans

(2008) Jacobien J. Hoogerwerf et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Molecular biology of inflammation and sepsis: A primer*

(2008) Ismail Cinel et al.   CRITICAL CARE MEDICINE

TAK-242 selectively suppresses Toll-like receptor 4-signaling mediated by the intracellular domain

(2008) Tomohiro Kawamoto et al.   EUROPEAN JOURNAL OF PHARMACOLOGY