PPARA: A Novel Genetic Determinant of CYP3A4 In Vitro and In Vivo

Inferring statin-induced gene regulatory relationships in primary human hepatocytes

(2011) Adrian Schröder et al.   BIOINFORMATICS

Effect of a new functionalCYP3A4polymorphism on calcineurin inhibitors’ dose requirements and trough blood levels in stable renal transplant patients

(2011) Laure Elens et al.   PHARMACOGENOMICS

Eight Common Genetic Variants Associated with Serum DHEAS Levels Suggest a Key Role in Ageing Mechanisms

(2011) Guangju Zhai et al.   PLoS Genetics

Cytochrome P450 genetic polymorphisms influence the serum concentration of calcineurin inhibitors in allogeneic hematopoietic SCT recipients

(2010) M Onizuka et al.   BONE MARROW TRANSPLANTATION

Profiling Induction of Cytochrome P450 Enzyme Activity by Statins Using a New Liquid Chromatography-Tandem Mass Spectrometry Cocktail Assay in Human Hepatocytes

(2010) D. M. Feidt et al.   DRUG METABOLISM AND DISPOSITION

Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver

(2010) X. Yang et al.   GENOME RESEARCH

Progesterone Receptor Membrane Component 1 Inhibits the Activity of Drug-Metabolizing Cytochromes P450 and Binds to Cytochrome P450 Reductase

(2010) E. Szczesna-Skorupa et al.   MOLECULAR PHARMACOLOGY

Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs

(2010) D Wang et al.   PHARMACOGENOMICS JOURNAL

Pathway-Targeted Pharmacogenomics of CYP1A2 in Human Liver

(2010) Kathrin Klein et al.   Frontiers in Pharmacology

ABCG2 Polymorphism Markedly Affects the Pharmacokinetics of Atorvastatin and Rosuvastatin

(2009) J E Keskitalo et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Transcriptional Regulation of Cytochrome P450 Genes by the Nuclear Receptor Hepatocyte Nuclear Factor 4-Alpha

(2009) Ramiro Jover et al.   CURRENT DRUG METABOLISM

The missing linkage: what pharmacogenetic associations are left to find inCYP3A?

(2009) Minoli A Perera   Expert Opinion on Drug Metabolism & Toxicology

Genetic Predictors of Interindividual Variability in Hepatic CYP3A4 Expression

(2009) V. Lamba et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Comparative Analysis of Gene Regulation by the Transcription Factor PPARα between Mouse and Human

(2009) Maryam Rakhshandehroo et al.   PLoS One

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

(2008) Ulrich M. Zanger et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

ABCB1 Haplotypes Differentially Affect the Pharmacokinetics of the Acid and Lactone Forms of Simvastatin and Atorvastatin

(2008) JE Keskitalo et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Interplay of Pregnane X receptor with Other Nuclear Receptors on Gene Regulation

(2008) Yun-Ping Lim et al.   Drug Metabolism and Pharmacokinetics

Post-transcriptional Regulation of Human Pregnane X Receptor by Micro-RNA Affects the Expression of Cytochrome P450 3A4

(2008) Shingo Takagi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prediction of CYP3A4 enzyme activity using haplotype tag SNPs in African Americans

(2008) M A Perera et al.   PHARMACOGENOMICS JOURNAL

PPARs Mediate Lipid Signaling in Inflammation and Cancer

(2008) Liliane Michalik et al.   PPAR Research

The Tangle of Nuclear Receptors that Controls Xenobiotic Metabolism and Transport: Crosstalk and Consequences

(2007) Jean-Marc Pascussi et al.   Annual Review of Pharmacology and Toxicology