标题
PPARA: A Novel Genetic Determinant of CYP3A4 In Vitro and In Vivo
作者
关键词
-
出版物
CLINICAL PHARMACOLOGY & THERAPEUTICS
Volume 91, Issue 6, Pages 1044-1052
出版商
Springer Nature
发表日期
2012-04-18
DOI
10.1038/clpt.2011.336
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Inferring statin-induced gene regulatory relationships in primary human hepatocytes
- (2011) Adrian Schröder et al. BIOINFORMATICS
- Effect of a new functionalCYP3A4polymorphism on calcineurin inhibitors’ dose requirements and trough blood levels in stable renal transplant patients
- (2011) Laure Elens et al. PHARMACOGENOMICS
- Eight Common Genetic Variants Associated with Serum DHEAS Levels Suggest a Key Role in Ageing Mechanisms
- (2011) Guangju Zhai et al. PLoS Genetics
- Cytochrome P450 genetic polymorphisms influence the serum concentration of calcineurin inhibitors in allogeneic hematopoietic SCT recipients
- (2010) M Onizuka et al. BONE MARROW TRANSPLANTATION
- Profiling Induction of Cytochrome P450 Enzyme Activity by Statins Using a New Liquid Chromatography-Tandem Mass Spectrometry Cocktail Assay in Human Hepatocytes
- (2010) D. M. Feidt et al. DRUG METABOLISM AND DISPOSITION
- Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver
- (2010) X. Yang et al. GENOME RESEARCH
- Progesterone Receptor Membrane Component 1 Inhibits the Activity of Drug-Metabolizing Cytochromes P450 and Binds to Cytochrome P450 Reductase
- (2010) E. Szczesna-Skorupa et al. MOLECULAR PHARMACOLOGY
- Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs
- (2010) D Wang et al. PHARMACOGENOMICS JOURNAL
- Pathway-Targeted Pharmacogenomics of CYP1A2 in Human Liver
- (2010) Kathrin Klein et al. Frontiers in Pharmacology
- ABCG2 Polymorphism Markedly Affects the Pharmacokinetics of Atorvastatin and Rosuvastatin
- (2009) J E Keskitalo et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Transcriptional Regulation of Cytochrome P450 Genes by the Nuclear Receptor Hepatocyte Nuclear Factor 4-Alpha
- (2009) Ramiro Jover et al. CURRENT DRUG METABOLISM
- The missing linkage: what pharmacogenetic associations are left to find inCYP3A?
- (2009) Minoli A Perera Expert Opinion on Drug Metabolism & Toxicology
- Genetic Predictors of Interindividual Variability in Hepatic CYP3A4 Expression
- (2009) V. Lamba et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Comparative Analysis of Gene Regulation by the Transcription Factor PPARα between Mouse and Human
- (2009) Maryam Rakhshandehroo et al. PLoS One
- Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation
- (2008) Ulrich M. Zanger et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- ABCB1 Haplotypes Differentially Affect the Pharmacokinetics of the Acid and Lactone Forms of Simvastatin and Atorvastatin
- (2008) JE Keskitalo et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Interplay of Pregnane X receptor with Other Nuclear Receptors on Gene Regulation
- (2008) Yun-Ping Lim et al. Drug Metabolism and Pharmacokinetics
- Post-transcriptional Regulation of Human Pregnane X Receptor by Micro-RNA Affects the Expression of Cytochrome P450 3A4
- (2008) Shingo Takagi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prediction of CYP3A4 enzyme activity using haplotype tag SNPs in African Americans
- (2008) M A Perera et al. PHARMACOGENOMICS JOURNAL
- PPARs Mediate Lipid Signaling in Inflammation and Cancer
- (2008) Liliane Michalik et al. PPAR Research
- The Tangle of Nuclear Receptors that Controls Xenobiotic Metabolism and Transport: Crosstalk and Consequences
- (2007) Jean-Marc Pascussi et al. Annual Review of Pharmacology and Toxicology
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