Determination of an Optimal Dosing Regimen for Fexinidazole, a Novel Oral Drug for the Treatment of Human African Trypanosomiasis: First-in-Human Studies

Genotoxicity profile of fexinidazole--a drug candidate in clinical development for human African trypanomiasis (sleeping sickness)

(2012) D. Tweats et al.   MUTAGENESIS

The Anti-Trypanosome Drug Fexinidazole Shows Potential for Treating Visceral Leishmaniasis

(2012) S. Wyllie et al.   Science Translational Medicine

In-Hospital Safety in Field Conditions of Nifurtimox Eflornithine Combination Therapy (NECT) for T. b. gambiense Sleeping Sickness

(2012) Caecilia Schmid et al.   PLoS Neglected Tropical Diseases

Human African Trypanosomiasis in the Democratic Republic of the Congo: A Looming Emergency?

(2012) Epco Hasker et al.   PLoS Neglected Tropical Diseases

Antitrypanosomal Activity of Fexinidazole, a New Oral Nitroimidazole Drug Candidate for Treatment of Sleeping Sickness

(2011) Marcel Kaiser et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cross-Resistance to Nitro Drugs and Implications for Treatment of Human African Trypanosomiasis

(2010) A. Y. Sokolova et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Fexinidazole – A New Oral Nitroimidazole Drug Candidate Entering Clinical Development for the Treatment of Sleeping Sickness

(2010) Els Torreele et al.   PLoS Neglected Tropical Diseases

Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial

(2009) Gerardo Priotto et al.   LANCET

Human African trypanosomiasis

(2009) Reto Brun et al.   LANCET

Near-Thorough QT Study as Part of a First-In-Man Study

(2008) Marek Malik et al.   JOURNAL OF CLINICAL PHARMACOLOGY

A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes

(2008) Shane R. Wilkinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA