Genotoxicity profile of fexinidazole--a drug candidate in clinical development for human African trypanomiasis (sleeping sickness)

1-Aryl-4-nitro-1H-imidazoles, a new promising series for the treatment of human African trypanosomiasis

(2011) Bernadette Bourdin Trunz et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cross-Resistance to Nitro Drugs and Implications for Treatment of Human African Trypanosomiasis

(2010) A. Y. Sokolova et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antitrypanosomal agents: treatment or threat?

(2010) Victor Sarli Issa et al.   LANCET

Chagas disease

(2010) Anis Rassi et al.   LANCET

Fexinidazole – A New Oral Nitroimidazole Drug Candidate Entering Clinical Development for the Treatment of Sleeping Sickness

(2010) Els Torreele et al.   PLoS Neglected Tropical Diseases

Epidemiologic evaluation of pharmaceuticals with limited evidence of carcinogenicity

(2009) Gary D. Friedman et al.   INTERNATIONAL JOURNAL OF CANCER

Lowering of 5-nitroimidazole's mutagenicity: Towards optimal antiparasitic pharmacophore

(2008) Maxime D. Crozet et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes

(2008) Shane R. Wilkinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genotoxicity and cell death induced by tinidazole (TNZ)

(2008) M.M. López Nigro et al.   TOXICOLOGY LETTERS