Pathogenesis of Chagas' Disease: Parasite Persistence and Autoimmunity

Chagas' Disease as a Foodborne Illness

(2016) KAREN SIGNORI PEREIRA et al.   JOURNAL OF FOOD PROTECTION

Stable CD8+ T Cell Memory during Persistent Trypanosoma cruzi Infection

(2014) L. M. Bixby et al.   JOURNAL OF IMMUNOLOGY

Infection with Trypanosoma cruzi Restricts the Repertoire of Parasite-Specific CD8+ T Cells Leading to Immunodominance

(2014) F. Tzelepis et al.   JOURNAL OF IMMUNOLOGY

Heat-Killed Trypanosoma cruzi Induces Acute Cardiac Damage and Polyantigenic Autoimmunity

(2011) Kevin M. Bonney et al.   PLoS One

Trypanosoma cruzi in the Chicken Model: Chagas-Like Heart Disease in the Absence of Parasitism

(2011) Antonio R. L. Teixeira et al.   PLoS Neglected Tropical Diseases

Chagas disease and gynecologic neoplasias

(2010) Venina Marcela Dominical et al.   Annals of Diagnostic Pathology

Origin of the cell nucleus, mitosis and sex: roles of intracellular coevolution

(2010) Thomas Cavalier-Smith   Biology Direct

Novel ruthenium complexes as potential drugs for Chagas's disease: enzyme inhibition and in vitro/in vivo trypanocidal activity

(2010) Jean Jerley Nogueira Silva et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Pre-mRNA Splicing Machinery of Trypanosomes: Complex or Simplified?

(2010) Arthur Günzl   EUKARYOTIC CELL

Molecular mechanisms of host cell invasion by Trypanosoma cruzi

(2010) Conrad L. Epting et al.   EXPERIMENTAL PARASITOLOGY

Generation of Trypanosoma cruzi-Specific CD8+ T-Cell Immunity Is Unaffected by the Absence of Type I Interferon Signaling

(2010) D. L. Martin et al.   INFECTION AND IMMUNITY

Trypanosoma cruziSubverts Host Cell Sialylation and May Compromise Antigen-specific CD8+T Cell Responses

(2010) Leonardo Freire-de-Lima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Familial Dilated Cardiomyopathy Secondary to Dystrophin Splice Site Mutation

(2010) Dita Obler et al.   JOURNAL OF CARDIAC FAILURE

ThePlasmodiumeukaryotic initiation factor-2α kinase IK2 controls the latency of sporozoites in the mosquito salivary glands

(2010) Min Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-6 Promotes NK Cell Production of IL-17 during Toxoplasmosis

(2010) Sara T. Passos et al.   JOURNAL OF IMMUNOLOGY

Redundant and Pathogenic Roles for IL-22 in Mycobacterial, Protozoan, and Helminth Infections

(2010) M. S. Wilson et al.   JOURNAL OF IMMUNOLOGY

Large Urban Outbreak of Orally Acquired Acute Chagas Disease at a School in Caracas, Venezuela

(2010) Belkisyolé Alarcón de Noya et al.   JOURNAL OF INFECTIOUS DISEASES

NF-κB1 contributes to T cell-mediated control of Toxoplasma gondii in the CNS

(2010) Tajie H. Harris et al.   JOURNAL OF NEUROIMMUNOLOGY

A role for host–parasite interactions in the horizontal transfer of transposons across phyla

(2010) Clément Gilbert et al.   NATURE

Inheritance of DNA Transferred from American Trypanosomes to Human Hosts

(2010) Mariana M. Hecht et al.   PLoS One

The impact of concomitant infections by Trypanosoma cruzi and intestinal helminths on the health of wild golden and golden-headed lion tamarins

(2010) Rafael V. Monteiro et al.   RESEARCH IN VETERINARY SCIENCE

Immunoactivation and immunopathogeny during active visceral leishmaniasis

(2010) Hiro Goto et al.   REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO

The Origin of TH2 Responses

(2010) R. L. Coffman   SCIENCE

IL-17 Produced during Trypanosoma cruzi Infection Plays a Central Role in Regulating Parasite-Induced Myocarditis

(2010) Paulo Marcos da Matta Guedes et al.   PLoS Neglected Tropical Diseases

Predominance of Trypanosoma cruzi genotypes in two reservoirs infected by sylvatic Triatoma infestans of an endemic area of Chile

(2009) S. Galuppo et al.   ACTA TROPICA

Chagas disease: A Latin American health problem becoming a world health problem

(2009) Gabriel A. Schmunis et al.   ACTA TROPICA

NIK and IKKβ interdependence in NF-κB signalling—Flux analysis of regulation through metabolites

(2009) Hong-Bum Kim et al.   BIOSYSTEMS

Chromosome level assembly of the hybrid Trypanosoma cruzi genome

(2009) D Brent Weatherly et al.   BMC GENOMICS

Environment, interactions between Trypanosoma cruzi and its host, and health

(2009) Antonio R. L. Teixeira et al.   Cadernos de Saude Publica

Heterogeneity and plasticity of T helper cells

(2009) Jinfang Zhu et al.   CELL RESEARCH

Differential Macrophage Polarization in Male and Female BALB/c Mice Infected With Coxsackievirus B3 Defines Susceptibility to Viral Myocarditis

(2009) Kang Li et al.   CIRCULATION RESEARCH

DoesToxoplasma gondiiInfection Affect the Levels of IgE and Cytokines (IL-5, IL-6, IL-10, IL-12, and TNF-alpha)?

(2009) Joanna Matowicka-Karna et al.   Clinical & Developmental Immunology

Changes inTrypanosoma cruzi–Specific Immune Responses after Treatment: Surrogate Markers of Treatment Efficacy

(2009) Susana A. Laucella et al.   CLINICAL INFECTIOUS DISEASES

CD8+ T cells in Trypanosoma cruzi infection

(2009) Angel M Padilla et al.   CURRENT OPINION IN IMMUNOLOGY

ERK/p38 MAP-kinases and PI3K are involved in the differential regulation of B7-H1 expression in DC subsets

(2009) Svetlana Karakhanova et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Left ventricular enlargement in coxsackievirus-B3 induced chronic myocarditis — ongoing inflammation and an imbalance of the matrix degrading system

(2009) Susanne Rutschow et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Internal priming: An opportunistic pathway for L1 and Alu retrotransposition in hominins

(2009) Deepa Srikanta et al.   GENE

Plasticity of CD4+ T Cell Lineage Differentiation

(2009) Liang Zhou et al.   IMMUNITY

12/15-Lipoxygenase-Dependent Myeloid Production of Interleukin-12 Is Essential for Resistance to Chronic Toxoplasmosis

(2009) M. K. Middleton et al.   INFECTION AND IMMUNITY

Perforin and Gamma Interferon Expression Are Required for CD4+ and CD8+ T-Cell-Dependent Protective Immunity against a Human Parasite, Trypanosoma cruzi, Elicited by Heterologous Plasmid DNA Prime-Recombinant Adenovirus 5 Boost Vaccination

(2009) B. C. G. de Alencar et al.   INFECTION AND IMMUNITY

Comparative phylogeography of Trypanosoma cruzi TCIIc: New hosts, association with terrestrial ecotopes, and spatial clustering

(2009) Arlei Marcili et al.   INFECTION GENETICS AND EVOLUTION

Flow cytometric analysis and microsatellite genotyping reveal extensive DNA content variation in Trypanosoma cruzi populations and expose contrasts between natural and experimental hybrids

(2009) Michael D. Lewis et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Evolution of the haem synthetic pathway in kinetoplastid flagellates: An essential pathway that is not essential after all?

(2009) Luděk Kořený et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Trypanosoma cruziand myoid cells from seminiferous tubules: interaction and relation with fibrous components of extracellular matrix in experimental Chagas’ disease

(2009) Luiz Otávio Pereira Carvalho et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Interleukin (IL)-23 mediatesToxoplasma gondii–induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17

(2009) Melba Muñoz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Roles of the ERK MAPK in the regulation of proinflammatory and apoptotic responses in chicken macrophages infected with H9N2 avian influenza virus

(2009) Z. Xing et al.   JOURNAL OF GENERAL VIROLOGY

IL-17 Promotes Progression of Cutaneous Leishmaniasis in Susceptible Mice

(2009) S. Lopez Kostka et al.   JOURNAL OF IMMUNOLOGY

Chronic Human Infection with Trypanosoma cruzi Drives CD4+ T Cells to Immune Senescence

(2009) M. C. Albareda et al.   JOURNAL OF IMMUNOLOGY

Infections and autoimmunity: the multifaceted relationship

(2009) P. Sfriso et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Proteolytic generation of kinins in tissues infected by Trypanosoma cruzi depends on CXC chemokine secretion by macrophages activated via Toll-like 2 receptors

(2009) Veronica Schmitz et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Kinetics of Systemic Cytokine and Brain Chemokine Gene Expression in Murine Toxoplasma Infection

(2009) Hernan Aviles et al.   JOURNAL OF PARASITOLOGY

Health Assessment of Free-Ranging Three-Banded (Tolypeutes matacus) and Nine-Banded (Dasypus novemcinctus) Armadillos in the Gran Chaco, Bolivia

(2009) Sharon L. Deem et al.   JOURNAL OF ZOO AND WILDLIFE MEDICINE

Trypanosoma cruzi: ancestral genomes and population structure

(2009) Sérgio DJ Pena et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Paleoparasitology of Chagas disease: a review

(2009) Adauto Araújo et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Immunological and non-immunological effects of cytokines and chemokines in the pathogenesis of chronic Chagas disease cardiomyopathy

(2009) Edecio Cunha-Neto et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Back to the future in Chagas disease: from animal models to patient cohort studies, progress in immunopathogenesis research

(2009) Julio Scharfstein et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

The utility of anti-trypomastigote lytic antibodies for determining cure of Trypanosoma cruzi infections in treated patients: an overview and perspectives

(2009) Antoniana Ursine Krettli   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Structural organization of Trypanosoma cruzi

(2009) Wanderley de Souza   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Current epidemiological trends for Chagas disease in Latin America and future challenges in epidemiology, surveillance and health policy

(2009) Álvaro Moncayo et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Probing into the diversity of trypanosomatid flagellates parasitizing insect hosts in South-West China reveals both endemism and global dispersal

(2009) Jan Votýpka et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

Epigenetic control of mammalian LINE-1 retrotransposon by retinoblastoma proteins

(2009) Diego E. Montoya-Durango et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle

(2009) Maximina H. Yun et al.   NATURE

Translesion DNA synthesis-assisted non-homologous end-joining of complex double-strand breaks prevents loss of DNA sequences in mammalian cells

(2009) Shay Covo et al.   NUCLEIC ACIDS RESEARCH

Transcriptionally active TFIIH of the early-diverged eukaryote Trypanosoma brucei harbors two novel core subunits but not a cyclin-activating kinase complex

(2009) Ju Huck Lee et al.   NUCLEIC ACIDS RESEARCH

The role of parasite persistence in pathogenesis of Chagas heart disease

(2009) F. R. S. GUTIERREZ et al.   PARASITE IMMUNOLOGY

Perspectives on the Trypanosoma cruzi–host cell receptor interactions

(2009) Fernando Villalta et al.   PARASITOLOGY RESEARCH

Deep phylogeny, ancestral groups and the four ages of life

(2009) T. Cavalier-Smith   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Perspectives on Trypanosoma cruzi–Induced Heart Disease (Chagas Disease)

(2009) Herbert B. Tanowitz et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

(2009) E. Lieberman-Aiden et al.   SCIENCE

Infections and autoimmunity – friends or foes?

(2009) Shaye Kivity et al.   TRENDS IN IMMUNOLOGY

Seroprevalence of Trypanosoma cruzi Among Eleven Potential Reservoir Species from Six States Across the Southern United States

(2009) Emily L. Brown et al.   VECTOR-BORNE AND ZOONOTIC DISEASES

Canine Chagas' Disease (American Trypanosomiasis) in North America

(2009) Stephen C. Barr   VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE

Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-γ, TNF-α, and low IL-10 production during the acute infection phase

(2009) Paulo M.M. Guedes et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Immunopathology of natural infection with Trypanosoma cruzi in dogs

(2009) Julio Vladimir Cruz-Chan et al.   VETERINARY PARASITOLOGY

The ecology of the Trypanosoma cruzi transmission cycle: Dispersion of zymodeme 3 (Z3) in wild hosts from Brazilian biomes

(2009) Cristiane Varella Lisboa et al.   VETERINARY PARASITOLOGY

Developments in the scientific understanding of rheumatoid arthritis

(2009) Jörg J Goronzy et al.   ARTHRITIS RESEARCH & THERAPY

Genetic Evidence That the Non-Homologous End-Joining Repair Pathway Is Involved in LINE Retrotransposition

(2009) Jun Suzuki et al.   PLoS Genetics

Differential Regional Immune Response in Chagas Disease

(2009) Juliana de Meis et al.   PLoS Neglected Tropical Diseases

Strong Host-Feeding Preferences of the Vector Triatoma infestans Modified by Vector Density: Implications for the Epidemiology of Chagas Disease

(2009) Ricardo E. Gürtler et al.   PLoS Neglected Tropical Diseases

Chronic American trypanosomiasis: parasite persistence in endomyocardial biopsies is associated with high-grade myocarditis

(2008) L. A. Benvenuti et al.   ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY

Proteomic map of Trypanosoma cruzi CL Brener: the reference strain of the genome project

(2008) Cátia Lacerda Sodré et al.   ARCHIVES OF MICROBIOLOGY

Skewing of X chromosome inactivation in autoimmunity

(2008) Pietro Invernizzi et al.   AUTOIMMUNITY

Recombinant cardiac myosin fragment induces experimental autoimmune myocarditis via activation of Th1 and Th17 immunity

(2008) Melvin D. Daniels et al.   AUTOIMMUNITY

Angiotensin-converting enzyme limits inflammation elicited by Trypanosoma cruzi cysteine proteases: a peripheral mechanism regulating adaptive immunity via the innate kinin pathway

(2008) Julio Scharfstein et al.   BIOLOGICAL CHEMISTRY

SnapShot: Vertebrate Transposons

(2008) Prabhat K. Mandal et al.   CELL

Pivotal role for TGF-β in infectious heart disease: The case of Trypanosoma cruzi infection and consequent Chagasic myocardiopathy

(2008) Tania C. Araújo-Jorge et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Benznidazole and Chagas disease: can an old drug be the answer to an old problem?

(2008) Charles Mady et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

The role of conserved residues of chagasin in the inhibition of cysteine peptidases

(2008) Flavia C.G. dos Reis et al.   FEBS LETTERS

LINE-Like Retrotransposition in Saccharomyces cerevisiae

(2008) C. Dong et al.   GENETICS

An alternative pathway for Alu retrotransposition suggests a role in DNA double-strand break repair

(2008) Deepa Srikanta et al.   GENOMICS

Molecular epidemiology of domestic and sylvatic Trypanosoma cruzi infection in rural northwestern Argentina

(2008) Marta V. Cardinal et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Predation and eukaryote cell origins: A coevolutionary perspective

(2008) T. Cavalier-Smith   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Beta-adrenergic blockers in chronic systolic heart failure secondary to Chagas' disease

(2008) Diego F. Dávila et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Natural Chagas disease in four baboons

(2008) Jeff T. Williams et al.   JOURNAL OF MEDICAL PRIMATOLOGY

The regulatory CD4+CD25+ T cells have a limited role on pathogenesis of infection with Trypanosoma cruzi

(2008) Policarpo A. Sales-Junior et al.   MICROBES AND INFECTION

Role of transposable elements in trypanosomatids

(2008) Frédéric Bringaud et al.   MICROBES AND INFECTION

Trypanosoma bruceiMitochondrial Ribosomes

(2008) Alena Zíková et al.   MOLECULAR & CELLULAR PROTEOMICS

Human Alu RNA Is a Modular Transacting Repressor of mRNA Transcription during Heat Shock

(2008) Peter D. Mariner et al.   MOLECULAR CELL

Trypanosoma cruzi calreticulin: A possible role in Chagas’ disease autoimmunity

(2008) Carolina Hager Ribeiro et al.   MOLECULAR IMMUNOLOGY

CLEC5A is critical for dengue-virus-induced lethal disease

(2008) Szu-Ting Chen et al.   NATURE

TcSNP: a database of genetic variation in Trypanosoma cruzi

(2008) A. A. Ackermann et al.   NUCLEIC ACIDS RESEARCH

Chagas disease cardiomyopathy: current concepts of an old disease

(2008) Angelina M.B. Bilate et al.   REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO

The coati (Nasua nasua, Carnivora, Procyonidae) as a reservoir host for the main lineages of Trypanosoma cruzi in the Pantanal region, Brazil

(2008) H.M. Herrera et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

MMEJ repair of double-strand breaks (director’s cut): deleted sequences and alternative endings

(2008) Mitch McVey et al.   TRENDS IN GENETICS

Numt-Mediated Double-Strand Break Repair Mitigates Deletions during Primate Genome Evolution

(2008) Einat Hazkani-Covo et al.   PLoS Genetics

Anti-muscarinic autoantibodies and vagal modulation in Chagas disease: Positive allosteric modulators vs desensitization and downregulation of M2 cardiac acetylcholine receptors

(2007) Diego F. Dávila et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Lateral transfer of the gene for a widely used marker, α-tubulin, indicated by a multi-protein study of the phylogenetic position of Andalucia (Excavata)

(2007) Alastair G.B. Simpson et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION