Interleukin (IL)-23 mediatesToxoplasma gondii–induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17

Protective Immunity to Systemic Infection with Attenuated Salmonella enterica serovar Enteritidis in the Absence of IL-12 Is Associated with IL-23-Dependent IL-22, but Not IL-17

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Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

(2009) Melanie A. Kleinschek et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-γ are not

(2009) Kerstin Wolk et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells

(2009) Sara Trifari et al.   NATURE IMMUNOLOGY

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

(2009) Thomas Duhen et al.   NATURE IMMUNOLOGY

Regulation of autoimmune arthritis by the pro-inflammatory cytokine interferon-γ

(2008) Eugene Y. Kim et al.   CLINICAL IMMUNOLOGY

Innate and Adaptive Interleukin-22 Protects Mice from Inflammatory Bowel Disease

(2008) Lauren A. Zenewicz et al.   IMMUNITY

Microbial Flora Drives Interleukin 22 Production in Intestinal NKp46+ Cells that Provide Innate Mucosal Immune Defense

(2008) Naoko Satoh-Takayama et al.   IMMUNITY

A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

(2008) Marina Cella et al.   NATURE

Influence of the transcription factor RORγt on the development of NKp46+ cell populations in gut and skin

(2008) Carmelo Luci et al.   NATURE IMMUNOLOGY

RORγt and commensal microflora are required for the differentiation of mucosal interleukin 22–producing NKp46+ cells

(2008) Stephanie L Sanos et al.   NATURE IMMUNOLOGY

A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses

(2008) Elisabetta Volpe et al.   NATURE IMMUNOLOGY

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

(2008) Yan Zheng et al.   NATURE MEDICINE

Matrix metalloproteinase-3 production by gut IgG plasma cells in chronic inflammatory bowel disease

(2007) John N. Gordon et al.   INFLAMMATORY BOWEL DISEASES