Molecular mechanism of substrate specificity for delta 6 desaturase fromMortierella alpinaandMicromonas pusilla

X-ray structure of a mammalian stearoyl-CoA desaturase

(2015) Yonghong Bai et al.   NATURE

Crystal structure of human stearoyl–coenzyme A desaturase in complex with substrate

(2015) Hui Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structure of human stearoyl–coenzyme A desaturase in complex with substrate

(2015) Hui Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Fungal Polyketide Synthase Product Chain-Length Control by Partnering Thiohydrolase

(2014) Angelica O. Zabala et al.   ACS Chemical Biology

Efficient production of triacylglycerols rich in docosahexaenoic acid (DHA) by osmo-heterotrophic marine protists

(2014) Ying Liu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Increased fatty acid unsaturation and production of arachidonic acid by homologous over-expression of the mitochondrial malic enzyme in Mortierella alpina

(2014) Guangfei Hao et al.   BIOTECHNOLOGY LETTERS

Elovl2 ablation demonstrates that systemic DHA is endogenously produced and is essential for lipid homeostasis in mice

(2014) Anna M. Pauter et al.   JOURNAL OF LIPID RESEARCH

Diversification of substrate specificities in teleostei Fads2: characterization of Δ4 and Δ6Δ5 desaturases ofChirostoma estor

(2014) Jorge Fonseca-Madrigal et al.   JOURNAL OF LIPID RESEARCH

Production of omega-3 eicosapentaenoic acid by metabolic engineering of Yarrowia lipolytica

(2013) Zhixiong Xue et al.   NATURE BIOTECHNOLOGY

Expression and Purification of Integral Membrane Fatty Acid Desaturases

(2013) Haiqin Chen et al.   PLoS One

Identification of a fatty acid ∆6-desaturase gene from the eicosapentaenoic acid-producing fungus Pythium splendens RBB-5

(2012) Ruijiao Zhang et al.   BIOTECHNOLOGY LETTERS

Δ6-Desaturase from Mortierella alpina: cDNA cloning, expression, and phylogenetic analysis

(2011) Jianmin Liu et al.   BIOTECHNOLOGY LETTERS

Functional characterization of a delta 6-desaturase gene from the black seabream (Acanthopagrus schlegeli)

(2011) Sun Hee Kim et al.   BIOTECHNOLOGY LETTERS

Cloning and characterization of a delta-6 desaturase encoding gene from Nannochloropsis oculata

(2011) Xiaolei Ma et al.   CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY

The Front-end Desaturase: Structure, Function, Evolution and Biotechnological Use

(2011) Dauenpen Meesapyodsuk et al.   LIPIDS

Genome Characterization of the Oleaginous Fungus Mortierella alpina

(2011) Lei Wang et al.   PLoS One

Identification and Characterization of Δ12, Δ6, and Δ5 Desaturases from the Green Microalga Parietochloris incisa

(2010) Umidjon Iskandarov et al.   LIPIDS

Metabolic engineering of omega-3 long-chain polyunsaturated fatty acids in plants using an acyl-CoA Δ6-desaturase with ω3-preference from the marine microalga Micromonas pusilla

(2009) James R. Petrie et al.   METABOLIC ENGINEERING

An alternative to fish oils: Metabolic engineering of oil-seed crops to produce omega-3 long chain polyunsaturated fatty acids

(2009) Mónica Venegas-Calerón et al.   PROGRESS IN LIPID RESEARCH

Evolution-related amino acids play important role in determining regioselectivity of fatty acid desaturase from Pichia pastoris

(2008) Xinxin Zhang et al.   MOLECULAR BIOLOGY REPORTS