Crystal structure of human stearoyl–coenzyme A desaturase in complex with substrate

An overview of patented small molecule stearoyl coenzyme-A desaturase inhibitors (2009 – 2013)

(2013) David A Powell   EXPERT OPINION ON THERAPEUTIC PATENTS

Opportunities and Challenges in Developing Stearoyl-Coenzyme A Desaturase-1 Inhibitors as Novel Therapeutics for Human Disease

(2013) Zaihui Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Crystal structure of quinol-dependent nitric oxide reductase from Geobacillus stearothermophilus

(2012) Yushi Matsumoto et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure and Mechanism of the Diiron Benzoyl-Coenzyme A Epoxidase BoxB

(2011) Liv J. Rather et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Roles of StearoylCoA Desaturase-1 in the Regulation of Cancer Cell Growth, Survival and Tumorigenesis

(2011) R. Ariel Igal   Cancers

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural Basis of Biological N2O Generation by Bacterial Nitric Oxide Reductase

(2010) T. Hino et al.   SCIENCE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

Stearoyl-CoA desaturase inhibitors: update on patented compounds

(2009) Gang Liu   EXPERT OPINION ON THERAPEUTIC PATENTS

Desaturases: Emerging Models for Understanding Functional Diversification of Diiron-containing Enzymes

(2009) John Shanklin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Low hepatic stearoyl-CoA desaturase 1 activity is associated with fatty liver and insulin resistance in obese humans

(2008) N. Stefan et al.   DIABETOLOGIA