Elucidation of monocyte/macrophage dynamics and function by intravital imaging

A dynamic spectrum of monocytes arising from the in situ reprogramming of CCR2+monocytes at a site of sterile injury

(2015) Daniela Dal-Secco et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cellular Level Brain Imaging in Behaving Mammals: An Engineering Approach

(2015) Elizabeth J.O. Hamel et al.   NEURON

Inflammation and Neuroprotection in Traumatic Brain Injury

(2015) Kara N. Corps et al.   JAMA Neurology

The Role of An Experimental Model of Atherosclerosis: apoE-knockout Mice in Developing New Drugs against Atherogenesis

(2015) Jacek Jawien   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

The role of lymph node sinus macrophages in host defense

(2014) Mirela Kuka et al.   Annals of the New York Academy of Sciences

Microglia Development and Function

(2014) Debasis Nayak et al.   Annual Review of Immunology

High-resolution intravital imaging reveals that blood-derived macrophages but not resident microglia facilitate secondary axonal dieback in traumatic spinal cord injury

(2014) Teresa A. Evans et al.   EXPERIMENTAL NEUROLOGY

Origin and Functions of Tissue Macrophages

(2014) Slava Epelman et al.   IMMUNITY

Development and Function of Dendritic Cell Subsets

(2014) Alexander Mildner et al.   IMMUNITY

Macrophages eliminate circulating tumor cells after monoclonal antibody therapy

(2014) Nuray Gül et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential roles of microglia and monocytes in the inflamed central nervous system

(2014) Ryo Yamasaki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

(2014) Elisa Gomez Perdiguero et al.   NATURE

Platelets: at the nexus of antimicrobial defence

(2014) Michael R. Yeaman   NATURE REVIEWS MICROBIOLOGY

Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain

(2014) Monica R.P. Elmore et al.   NEURON

An MHC II-Dependent Activation Loop between Adipose Tissue Macrophages and CD4+ T Cells Controls Obesity-Induced Inflammation

(2014) Kae Won Cho et al.   Cell Reports

Ly6Chigh Monocytes Become Alternatively Activated Macrophages in Schistosome Granulomas with Help from CD4+ Cells

(2014) Natasha M. Girgis et al.   PLoS Pathogens

Real-Time Imaging Reveals the Dynamics of Leukocyte Behaviour during Experimental Cerebral Malaria Pathogenesis

(2014) Saparna Pai et al.   PLoS Pathogens

Live Imaging of the Lung

(2013) Mark R. Looney et al.   Annual Review of Physiology

Dynamic imaging reveals promiscuous crosspresentation of blood-borne antigens to naive CD8+ T cells in the bone marrow

(2013) I. Milo et al.   BLOOD

Nr4a1-Dependent Ly6Clow Monocytes Monitor Endothelial Cells and Orchestrate Their Disposal

(2013) Leo M. Carlin et al.   CELL

Immunological Goings-on in Visceral Adipose Tissue

(2013) Diane Mathis   Cell Metabolism

Class II Major Histocompatibility Complex Plays an Essential Role in Obesity-Induced Adipose Inflammation

(2013) Tuo Deng et al.   Cell Metabolism

The future of immunoimaging - Deeper, bigger, more precise, and definitively more colorful

(2013) Jianyong Tang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Recruitment of Beneficial M2 Macrophages to Injured Spinal Cord Is Orchestrated by Remote Brain Choroid Plexus

(2013) Ravid Shechter et al.   IMMUNITY

Two-Photon Intravital Imaging of Lungs during Anthrax Infection Reveals Long-Lasting Macrophage-Dendritic Cell Contacts

(2013) Daniel Fiole et al.   INFECTION AND IMMUNITY

Imaging cell biology in live animals: Ready for prime time

(2013) Roberto Weigert et al.   JOURNAL OF CELL BIOLOGY

The mechanism of anti-CD20–mediated B cell depletion revealed by intravital imaging

(2013) Fabricio Montalvao et al.   JOURNAL OF CLINICAL INVESTIGATION

Transcranial amelioration of inflammation and cell death after brain injury

(2013) Theodore L. Roth et al.   NATURE

Immune surveillance by the liver

(2013) Craig N Jenne et al.   NATURE IMMUNOLOGY

Nucleation of platelets with blood-borne pathogens on Kupffer cells precedes other innate immunity and contributes to bacterial clearance

(2013) Connie H Y Wong et al.   NATURE IMMUNOLOGY

A combination of fluorescent NFAT and H2B sensors uncovers dynamics of T cell activation in real time during CNS autoimmunity

(2013) Dmitri Lodygin et al.   NATURE MEDICINE

Macrophage contact induces RhoA GTPase signaling to trigger tumor cell intravasation

(2013) M Roh-Johnson et al.   ONCOGENE

A deficiency in CCR2+ monocytes: the hidden side of Alzheimer's disease

(2013) Gaëlle Naert et al.   Journal of Molecular Cell Biology

Real-Time In Vivo Imaging Reveals the Ability of Monocytes to Clear Vascular Amyloid Beta

(2013) Jean-Philippe Michaud et al.   Cell Reports

Intravital Placenta Imaging Reveals Microcirculatory Dynamics Impact on Sequestration and Phagocytosis of Plasmodium-Infected Erythrocytes

(2013) Luciana Vieira de Moraes et al.   PLoS Pathogens

Type I Interferon Programs Innate Myeloid Dynamics and Gene Expression in the Virally Infected Nervous System

(2013) Debasis Nayak et al.   PLoS Pathogens

Managing Inflammation after Spinal Cord Injury through Manipulation of Macrophage Function

(2013) Yi Ren et al.   NEURAL PLASTICITY

High-resolution molecular imaging via intravital microscopy: illuminating vascular biology in vivo

(2012) Viviany R. Taqueti et al.   Integrative Biology

Intravital 2-photon imaging of leukocyte trafficking in beating heart

(2012) Wenjun Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

(2012) Marie-Luise von Brühl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Imaging interactions between macrophages and tumour cells that are involved in metastasisin vivoandin vitro

(2012) A. DOVAS et al.   JOURNAL OF MICROSCOPY

Two-Photon Imaging of Microbial Immunity in Living Tissues

(2012) Jasmin Herz et al.   MICROSCOPY AND MICROANALYSIS

The molecular basis of leukocyte recruitment and its deficiencies

(2012) Sarah Schmidt et al.   MOLECULAR IMMUNOLOGY

Multiphoton imaging reveals a new leukocyte recruitment paradigm in the glomerulus

(2012) Sapna Devi et al.   NATURE MEDICINE

Anti-CD20 Antibody Therapy for B-Cell Lymphomas

(2012) David G. Maloney   NEW ENGLAND JOURNAL OF MEDICINE

Differential macrophage programming in the tumor microenvironment

(2012) Brian Ruffell et al.   TRENDS IN IMMUNOLOGY

Real-time in vivo imaging of the beating mouse heart at microscopic resolution

(2012) Sungon Lee et al.   Nature Communications

Two-Photon Imaging within the Murine Thorax without Respiratory and Cardiac Motion Artifact

(2011) Robert G. Presson et al.   AMERICAN JOURNAL OF PATHOLOGY

Intravital Imaging

(2011) Mikael J. Pittet et al.   CELL

Intravital Microscopy on Atherosclerosis in Apolipoprotein E–Deficient Mice Establishes Microvessels as Major Entry Pathways for Leukocytes to Advanced Lesions

(2011) Einar E. Eriksson   CIRCULATION

Bone Marrow–Specific Deficiency of Nuclear Receptor Nur77 Enhances Atherosclerosis

(2011) Anouk A.J. Hamers et al.   CIRCULATION RESEARCH

NR4A1 (Nur77) Deletion Polarizes Macrophages Toward an Inflammatory Phenotype and Increases Atherosclerosis

(2011) Richard N. Hanna et al.   CIRCULATION RESEARCH

Mena invasive (MenaINV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer

(2011) E. T. Roussos et al.   JOURNAL OF CELL SCIENCE

Intravital microscopy: new insights into metastasis of tumors

(2011) E. Beerling et al.   JOURNAL OF CELL SCIENCE

Chemokines control naive CD8+T cell selection of optimal lymph node antigen presenting cells

(2011) Heather D. Hickman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Deficient CX3CR1 Signaling Promotes Recovery after Mouse Spinal Cord Injury by Limiting the Recruitment and Activation of Ly6Clo/iNOS+ Macrophages

(2011) D. J. Donnelly et al.   JOURNAL OF NEUROSCIENCE

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

(2011) Bin-Zhi Qian et al.   NATURE

Progress and challenges in translating the biology of atherosclerosis

(2011) Peter Libby et al.   NATURE

The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C− monocytes

(2011) Richard N Hanna et al.   NATURE IMMUNOLOGY

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Interferon-α increases monocyte migration via platelet-monocyte interaction in murine intestinal microvessels

(2010) M. Higashiyama et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Liver antigen-presenting cells

(2010) Ian Nicholas Crispe   JOURNAL OF HEPATOLOGY

LFA-1 and Mac-1 Define Characteristically Different Intralumenal Crawling and Emigration Patterns for Monocytes and Neutrophils In Situ

(2010) R. Sumagin et al.   JOURNAL OF IMMUNOLOGY

An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells

(2010) Woo-Yong Lee et al.   NATURE IMMUNOLOGY

Stabilized imaging of immune surveillance in the mouse lung

(2010) Mark R Looney et al.   NATURE METHODS

Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

(2010) Lars M. Ittner et al.   NATURE REVIEWS NEUROSCIENCE

Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice

(2010) Noah Saederup et al.   PLoS One

In vivo two-photon imaging reveals monocyte-dependent neutrophil extravasation during pulmonary inflammation

(2010) D. Kreisel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Dynamic Imaging of Experimental Leishmania donovani-Induced Hepatic Granulomas Detects Kupffer Cell-Restricted Antigen Presentation to Antigen-Specific CD8+ T Cells

(2010) Lynette Beattie et al.   PLoS Pathogens

The Liver as a Lymphoid Organ

(2009) Ian Nicholas Crispe   Annual Review of Immunology

Heterogeneous In Vivo Behavior of Monocyte Subsets in Atherosclerosis

(2009) Filip K. Swirski et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Fcγ receptor-dependent expansion of a hyperactive monocyte subset in lupus-prone mice

(2009) Marie-Laure Santiago-Raber et al.   ARTHRITIS AND RHEUMATISM

Dynamics of T Cell, Antigen-Presenting Cell, and Pathogen Interactions during Recall Responses in the Lymph Node

(2009) Tatyana Chtanova et al.   IMMUNITY

CX3CR1+CD115+CD135+common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation

(2009) Cedric Auffray et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions

(2009) Ingo Bartholomäus et al.   NATURE

Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation

(2009) Tri Giang Phan et al.   NATURE IMMUNOLOGY

Infiltrating Blood-Derived Macrophages Are Vital Cells Playing an Anti-inflammatory Role in Recovery from Spinal Cord Injury in Mice

(2009) Ravid Shechter et al.   PLOS MEDICINE

Dynamic Imaging of CD8+ T Cells and Dendritic Cells during Infection with Toxoplasma gondii

(2009) Beena John et al.   PLoS Pathogens

Choreography of Cell Motility and Interaction Dynamics Imaged by Two-Photon Microscopy in Lymphoid Organs

(2008) Michael D. Cahalan et al.   Annual Review of Immunology

Monocyte-Mediated Defense Against Microbial Pathogens

(2008) Natalya V. Serbina et al.   Annual Review of Immunology

ApoE−/−/Lysozyme MEGFP/EGFP mice as a versatile model to study monocyte and neutrophil trafficking in atherosclerosis

(2008) Pierre Rotzius et al.   ATHEROSCLEROSIS

Elie Metchnikoff: Father of natural immunity

(2008) Siamon Gordon   EUROPEAN JOURNAL OF IMMUNOLOGY

Lymphocytic choriomeningitis infection of the central nervous system

(2008) Silvia et al.   Frontiers in Bioscience-Landmark

Macrophage and T Cell Dynamics during the Development and Disintegration of Mycobacterial Granulomas

(2008) Jackson G. Egen et al.   IMMUNITY

Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis

(2008) Jiyun V. Kim et al.   NATURE

Direct priming of antiviral CD8+ T cells in the peripheral interfollicular region of lymph nodes

(2008) Heather D Hickman et al.   NATURE IMMUNOLOGY