The tryptophan metabolite picolinic acid suppresses proliferation and metabolic activity of CD4+ T cells and inhibits c-Myc activation

STAT3 governs hyporesponsiveness and granzyme B-dependent suppressive capacity in human CD4+ T cells

(2015) Klaus G. Schmetterer et al.   FASEB JOURNAL

mTOR/MYC Axis Regulates O-GlcNAc Transferase Expression and O-GlcNAcylation in Breast Cancer

(2015) V. L. Sodi et al.   MOLECULAR CANCER RESEARCH

Heme Oxygenase-1 Drives Metaflammation and Insulin Resistance in Mouse and Man

(2014) Alexander Jais et al.   CELL

Metabolic Reprogramming towards Aerobic Glycolysis Correlates with Greater Proliferative Ability and Resistance to Metabolic Inhibition in CD8 versus CD4 T Cells

(2014) Yilin Cao et al.   PLoS One

Azithromycin suppresses CD4+ T-cell activation by direct modulation of mTOR activity

(2014) F. Ratzinger et al.   Scientific Reports

Targeting T Cell Immunometabolism for Cancer Immunotherapy; Understanding the Impact of the Tumor Microenvironment

(2014) Mary B. Mockler et al.   Frontiers in Oncology

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

Destabilization of peptide:MHC interaction induces IL-2 resistant anergy in diabetogenic T cells

(2013) Lindsay J. Edwards et al.   JOURNAL OF AUTOIMMUNITY

Distinct TCR signaling pathways drive proliferation and cytokine production in T cells

(2013) Clifford S Guy et al.   NATURE IMMUNOLOGY

MYC on the Path to Cancer

(2012) Chi V. Dang   CELL

The Sedoheptulose Kinase CARKL Directs Macrophage Polarization through Control of Glucose Metabolism

(2012) Arvand Haschemi et al.   Cell Metabolism

Metabolic checkpoints in activated T cells

(2012) Ruoning Wang et al.   NATURE IMMUNOLOGY

The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation

(2011) Ruoning Wang et al.   IMMUNITY

The effects of Cyclosporine A and azathioprine on human T cells activated by different costimulatory signals

(2011) Judith Leitner et al.   IMMUNOLOGY LETTERS

Cbl-b and Itch: Key Regulators of Peripheral T-cell Tolerance

(2010) K. Venuprasad   CANCER RESEARCH

Tryptophan metabolite 3-hydroxyanthranilic acid selectively induces activated T cell death via intracellular GSH depletion

(2010) Sun-Mi Lee et al.   IMMUNOLOGY LETTERS

T cell stimulator cells, an efficient and versatile cellular system to assess the role of costimulatory ligands in the activation of human T cells

(2010) Judith Leitner et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Anergic CD4+ T Cells Form Mature Immunological Synapses with Enhanced Accumulation of c-Cbl and Cbl-b

(2010) M. Doherty et al.   JOURNAL OF IMMUNOLOGY

Transforming growth factor beta 1 (TGF-β1) and rapamycin synergize to effectively suppress human T cell responses via upregulation of FoxP3+ Tregs

(2010) Koichi Kawamoto et al.   TRANSPLANT IMMUNOLOGY

Abl tyrosine kinases in T-cell signaling

(2009) Jing Jin Gu et al.   IMMUNOLOGICAL REVIEWS

Translational control of c-MYC by rapamycin promotes terminal myeloid differentiation

(2008) M. Wall et al.   BLOOD

The role of indoleamine 2,3-dioxygenase in the induction of immune tolerance: focus on hematology

(2008) A. Curti et al.   BLOOD

IL-2 signaling prevents T cell anergy by inhibiting the expression of anergy-inducing genes

(2008) Myrianne Duré et al.   MOLECULAR IMMUNOLOGY