Cytokines in immune-mediated inflammatory myopathies: cellular sources, multiple actions and therapeutic implications

Dermatomyositis, polymyositis and immune-mediated necrotising myopathies

(2015) Yue-Bei Luo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Preferential infiltration of interleukin-4-producing CXCR4+T cells in the lesional muscle but not skin of patients with dermatomyositis

(2014) T. Fujiyama et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Abatacept as a successful therapy for myositis—a case-based review

(2014) Anne M. Kerola et al.   CLINICAL RHEUMATOLOGY

Restoring the balance: immunotherapeutic combinations for autoimmune disease

(2014) D. E. Smilek et al.   Disease Models & Mechanisms

The role of interleukin-17 in immune-mediated inflammatory myopathies and possible therapeutic implications

(2014) Ellen M. Moran et al.   NEUROMUSCULAR DISORDERS

An analysis of the sensitivity and specificity of MHC-I and MHC-II immunohistochemical staining in muscle biopsies for the diagnosis of inflammatory myopathies

(2014) Pedro M. Rodríguez Cruz et al.   NEUROMUSCULAR DISORDERS

Th1 Response and Systemic Treg Deficiency in Inclusion Body Myositis

(2014) Yves Allenbach et al.   PLoS One

Activated IL-22 pathway occurs in the muscle tissues of patients with polymyositis or dermatomyositis and is correlated with disease activity

(2014) Francesco Ciccia et al.   RHEUMATOLOGY

Roles of mast cells in the pathogenesis of inflammatory myopathy

(2014) Masaya Yokota et al.   ARTHRITIS RESEARCH & THERAPY

TWEAK/Fn14 Signaling Axis Mediates Skeletal Muscle Atrophy and Metabolic Dysfunction

(2014) Shuichi Sato et al.   Frontiers in Immunology

Anakinra treatment in patients with refractory inflammatory myopathies and possible predictive response biomarkers: a mechanistic study with 12 months follow-up

(2013) Mei Zong et al.   ANNALS OF THE RHEUMATIC DISEASES

A phase 1b clinical trial evaluating sifalimumab, an anti-IFN-α monoclonal antibody, shows target neutralisation of a type I IFN signature in blood of dermatomyositis and polymyositis patients

(2013) Brandon W Higgs et al.   ANNALS OF THE RHEUMATIC DISEASES

Correlation between the Frequency of Th17 Cell and the Expression of MicroRNA-206 in Patients with Dermatomyositis

(2013) Xinyi Tang et al.   Clinical & Developmental Immunology

Diagnosis, pathogenesis and treatment of myositis: recent advances

(2013) P. -O. Carstens et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Cytokine synergy: An underappreciated contributor to innate anti-viral immunity

(2013) Eric Bartee et al.   CYTOKINE

Myositis in a patient with familial Mediterranean fever and spondyloarthritis successfully treated with anakinra

(2013) Charline Estublier et al.   JOINT BONE SPINE

Complement-mediated muscle cell lysis: A possible mechanism of myonecrosis in anti-SRP associated necrotizing myopathy (ASANM)

(2013) Arada Rojana-udomsart et al.   JOURNAL OF NEUROIMMUNOLOGY

The effect of anakinra, an IL1 receptor antagonist, in patients with sporadic inclusion body myositis (sIBM): A small pilot study

(2013) Michalis L. Kosmidis et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

A critical role for immature muscle precursors in myositis

(2013) Anne Tournadre et al.   Nature Reviews Rheumatology

The nonnecrotic invaded muscle fibers of polymyositis and sporadic inclusion body myositis: On the interplay of chemokines and stress proteins

(2013) Boel De Paepe et al.   NEUROSCIENCE LETTERS

Suppression of soluble T cell-associated proteins by an anti-interferon-  monoclonal antibody in adult patients with dermatomyositis or polymyositis

(2013) X. Guo et al.   RHEUMATOLOGY

Immune mechanisms in polymyositis and dermatomyositis and potential targets for therapy

(2013) P. Venalis et al.   RHEUMATOLOGY

Inhibition of Myogenic MicroRNAs 1, 133, and 206 by Inflammatory Cytokines Links Inflammation and Muscle Degeneration in Adult Inflammatory Myopathies

(2013) Robert W. Georgantas et al.   Arthritis & Rheumatology

Idiopathic inflammatory myopathies: pathogenic mechanisms of muscle weakness

(2013) Sree Rayavarapu et al.   Skeletal Muscle

TWEAK in Inclusion-Body Myositis Muscle

(2012) Roberta Morosetti et al.   AMERICAN JOURNAL OF PATHOLOGY

Immune-Mediated Necrotizing Myopathy Is Characterized by a Specific Th1-M1 Polarized Immune Profile

(2012) Corinna Preuße et al.   AMERICAN JOURNAL OF PATHOLOGY

Provision of an explanation for the inefficacy of immunotherapy in sporadic inclusion body myositis: Quantitative assessment of inflammation and β-amyloid in the muscle

(2012) Jana Zschüntzsch et al.   ARTHRITIS AND RHEUMATISM

Editorial: The efficacy of rituximab in refractory myositis: The jury is still out

(2012) Marianne de Visser   ARTHRITIS AND RHEUMATISM

Rituximab in the treatment of refractory adult and juvenile dermatomyositis and adult polymyositis: A randomized, placebo-phase trial

(2012) Chester V. Oddis et al.   ARTHRITIS AND RHEUMATISM

Pathogenesis and therapy of inclusion body myositis

(2012) Steven A. Greenberg   CURRENT OPINION IN NEUROLOGY

Myositis autoantibodies

(2012) Livia Casciola-Rosen et al.   CURRENT OPINION IN RHEUMATOLOGY

TWEAK promotes the production of Interleukin-17 in rheumatoid arthritis

(2012) Jin-Sil Park et al.   CYTOKINE

Target Specificity of an Autoreactive Pathogenic Human γδ-T Cell Receptor in Myositis

(2012) Jessica Bruder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The dual roles of inflammatory cytokines and chemokines in the regulation of autoimmune diseases and their clinical implications

(2012) Idit Shachar et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Pathogenic Considerations in Sporadic Inclusion-Body Myositis, a Degenerative Muscle Disease Associated With Aging and Abnormalities of Myoproteostasis

(2012) Valerie Askanas et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Abatacept and Sodium Thiosulfate for Treatment of Recalcitrant Juvenile Dermatomyositis Complicated by Ulceration and Calcinosis

(2012) Bita Arabshahi et al.   JOURNAL OF PEDIATRICS

Targeting IL-17 and TH17 cells in chronic inflammation

(2012) Pierre Miossec et al.   NATURE REVIEWS DRUG DISCOVERY

Review: Immune-mediated necrotizing myopathies - a heterogeneous group of diseases with specific myopathological features

(2012) W. Stenzel et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Interferon and Biologic Signatures in Dermatomyositis Skin: Specificity and Heterogeneity across Diseases

(2012) David Wong et al.   PLoS One

Type 1 interferons and myositis

(2012) Steven A Greenberg   ARTHRITIS RESEARCH & THERAPY

Interleukin-17 in Inflammatory Myopathies

(2012) Anne Tournadre et al.   Current Rheumatology Reports

Novel approaches in the treatment of myositis and myopathies

(2012) Jemima Albayda et al.   Therapeutic Advances in Musculoskeletal Disease

Inclusion Body Myositis

(2011) Jana Ivanidze et al.   AMERICAN JOURNAL OF PATHOLOGY

A randomized, pilot trial of etanercept in dermatomyositis

(2011)   ANNALS OF NEUROLOGY

Interleukin-27: A master regulator in inflammation

(2011) Ursula Fearon   ARTHRITIS AND RHEUMATISM

Immature muscle precursors are a source of interferon-β in myositis: Role of Toll-like receptor 3 activation and contribution to HLA class I up-regulation

(2011) Anne Tournadre et al.   ARTHRITIS AND RHEUMATISM

Pathogenesis and therapies of immune-mediated myopathies

(2011) Marinos C. Dalakas   AUTOIMMUNITY REVIEWS

Acquired immune and inflammatory myopathies

(2011) Alan Pestronk   CURRENT OPINION IN RHEUMATOLOGY

Relationship between disease activity and type 1 interferon- and other cytokine-inducible gene expression in blood in dermatomyositis and polymyositis

(2011) S A Greenberg et al.   GENES AND IMMUNITY

Identification of activated cytokine pathways in the blood of systemic lupus erythematosus, myositis, rheumatoid arthritis, and scleroderma patients

(2011) Brandon W. HIGGS et al.   International Journal of Rheumatic Diseases

Abatacept for treatment of refractory polymyositis

(2011) Jorge L. Musuruana et al.   JOINT BONE SPINE

Pathogenesis, classification and treatment of inflammatory myopathies

(2011) Mei Zong et al.   Nature Reviews Rheumatology

Efficacy and safety of rituximab in the treatment of refractory inflammatory myopathies in adults: results from the AIR registry

(2011) M. Couderc et al.   RHEUMATOLOGY

Therapeutic effect of tocilizumab on two patients with polymyositis

(2011) M. Narazaki et al.   RHEUMATOLOGY

Type I interferon pathway in adult and juvenile dermatomyositis

(2011) Emily C Baechler et al.   ARTHRITIS RESEARCH & THERAPY

Therapeutic Approaches in Myositis

(2011) Rohit Aggarwal et al.   Current Rheumatology Reports

Interferon   is associated with type 1 interferon-inducible gene expression in dermatomyositis

(2010) A. P. Liao et al.   ANNALS OF THE RHEUMATIC DISEASES

Lesional and nonlesional skin from patients with untreated juvenile dermatomyositis displays increased numbers of mast cells and mature plasmacytoid dendritic cells

(2010) Sheela Shrestha et al.   ARTHRITIS AND RHEUMATISM

A novel autoantibody recognizing 200-kd and 100-kd proteins is associated with an immune-mediated necrotizing myopathy

(2010) Lisa Christopher-Stine et al.   ARTHRITIS AND RHEUMATISM

Autoantibodies against 3-hydroxy-3-methylglutaryl-coenzyme A reductase in patients with statin-associated autoimmune myopathy

(2010) Andrew L. Mammen et al.   ARTHRITIS AND RHEUMATISM

Characterization of regulatory T cells in patients with dermatomyositis

(2010) E. Antiga et al.   JOURNAL OF AUTOIMMUNITY

Can muscle regeneration fail in chronic inflammation: a weakness in inflammatory myopathies?

(2010) I. Loell et al.   JOURNAL OF INTERNAL MEDICINE

Idiopathic inflammatory myopathies

(2010) Mazen M. Dimachkie   JOURNAL OF NEUROIMMUNOLOGY

Interleukin-6 and type I interferon-regulated genes and chemokines mark disease activity in dermatomyositis

(2009) Hatice Bilgic et al.   ARTHRITIS AND RHEUMATISM

Expression of the dermatomyositis autoantigen Mi-2 in regenerating muscle

(2009) Andrew L. Mammen et al.   ARTHRITIS AND RHEUMATISM

Idiopathic inflammatory myopathies and the classical NF-κB complex: Current insights and implications for therapy

(2009) Kim K. Creus et al.   AUTOIMMUNITY REVIEWS

Th1 and Th17 balance in inflammatory myopathies: Interaction with dendritic cells and possible link with response to high-dose immunoglobulins

(2009) Anne Tournadre et al.   CYTOKINE

T Cell Infiltrates in the Muscles of Patients with Dermatomyositis and Polymyositis Are Dominated by CD28null T Cells

(2009) A. E. R. Fasth et al.   JOURNAL OF IMMUNOLOGY

Human rheumatoid arthritis tissue production of IL-17A drives matrix and cartilage degradation: synergy with tumour necrosis factor-α, Oncostatin M and response to biologic therapies

(2009) Ellen M Moran et al.   ARTHRITIS RESEARCH & THERAPY

Interrelation of inflammation and APP in sIBM: IL-1β induces accumulation of β-amyloid in skeletal muscle

(2008) Jens Schmidt et al.   BRAIN

Antisynthetase syndrome with refractory polyarthritis and fever successfully treated with the IL-1 receptor antagonist, anakinra: A case report

(2008) Antonio Furlan et al.   JOINT BONE SPINE

Foxp3 expression in cutaneous T-cell lymphocytic infiltrates

(2008) Garron J. Solomon et al.   JOURNAL OF CUTANEOUS PATHOLOGY

Review: Therapeutic advances and future prospects in immune-mediated inflammatory myopathies

(2008) Marinos C. Dalakas   Therapeutic Advances in Neurological Disorders