Idiopathic inflammatory myopathies: pathogenic mechanisms of muscle weakness

TWEAK in Inclusion-Body Myositis Muscle

(2012) Roberta Morosetti et al.   AMERICAN JOURNAL OF PATHOLOGY

Effects of immunosuppressive treatment on interleukin-15 and interleukin-15 receptor α expression in muscle tissue of patients with polymyositis or dermatomyositis

(2012) Mei Zong et al.   ANNALS OF THE RHEUMATIC DISEASES

Interleukin-1 and tumor necrosis factor α blockade treatment of experimental polymyositis in mice

(2012) Takahiko Sugihara et al.   ARTHRITIS AND RHEUMATISM

The molecular basis of skeletal muscle weakness in a mouse model of inflammatory myopathy

(2012) William Coley et al.   ARTHRITIS AND RHEUMATISM

Myositis autoantibodies

(2012) Livia Casciola-Rosen et al.   CURRENT OPINION IN RHEUMATOLOGY

Characterization of TLR4-mediated auto-antibody production in a mouse model of histidyl-tRNA synthetase-induced myositis

(2012) Lisa Harlow et al.   Innate Immunity

Anti-SAE antibodies in autoimmune myositis: Identification by unlabelled protein immunoprecipitation in an Italian patient cohort

(2012) Elena Tarricone et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Toll-Like Receptors Promote Inflammation in Idiopathic Inflammatory Myopathies

(2012) Anna Brunn et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Activation of the γ-secretase complex and presence of γ-secretase-activating protein may contribute to Aβ42 production in sporadic inclusion-body myositis muscle fibers

(2012) Anna Nogalska et al.   NEUROBIOLOGY OF DISEASE

TLR2/MyD88/NF-κB Pathway, Reactive Oxygen Species, Potassium Efflux Activates NLRP3/ASC Inflammasome during Respiratory Syncytial Virus Infection

(2012) Jesus Segovia et al.   PLoS One

Plasmacytoid dendritic cells control T-cell response to chronic viral infection

(2012) L. Cervantes-Barragan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resistin in idiopathic inflammatory myopathies

(2012) Mária Filková et al.   ARTHRITIS RESEARCH & THERAPY

Endoplasmic Reticulum Stress in Skeletal Muscle Homeostasis and Disease

(2012) Sree Rayavarapu et al.   Current Rheumatology Reports

The role of TRAIL in mediating autophagy in myositis skeletal muscle: A potential nonimmune mechanism of muscle damage

(2011) Heather M. Alger et al.   ARTHRITIS AND RHEUMATISM

Correlation of anti-signal recognition particle autoantibody levels with creatine kinase activity in patients with necrotizing myopathy

(2011) Olivier Benveniste et al.   ARTHRITIS AND RHEUMATISM

Myositis-specific anti-155/140 autoantibodies target transcription intermediary factor 1 family proteins

(2011) Manabu Fujimoto et al.   ARTHRITIS AND RHEUMATISM

Relationship between disease activity and type 1 interferon- and other cytokine-inducible gene expression in blood in dermatomyositis and polymyositis

(2011) S A Greenberg et al.   GENES AND IMMUNITY

Type I interferon and Toll-like receptor expression characterizes inflammatory myopathies

(2011) C. Cappelletti et al.   NEUROLOGY

Heat shock protein families 70 and 90 in Duchenne muscular dystrophy and inflammatory myopathy: Balancing muscle protection and destruction

(2011) Boel De Paepe et al.   NEUROMUSCULAR DISORDERS

The neurotrophin receptor p75NTR is induced on mature myofibres in inflammatory myopathies and promotes myotube survival to inflammatory stress

(2011) E. Colombo et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Sporadic inclusion-body myositis: Conformational multifactorial ageing-related degenerative muscle disease associated with proteasomal and lysosomal inhibition, endoplasmic reticulum stress, and accumulation of amyloid-β42 oligomers and phosphorylated tau

(2011) Valerie Askanas et al.   PRESSE MEDICALE

Inflammasome Up-Regulation and Activation in Dysferlin-Deficient Skeletal Muscle

(2010) Rashmi Rawat et al.   AMERICAN JOURNAL OF PATHOLOGY

A novel autoantibody recognizing 200-kd and 100-kd proteins is associated with an immune-mediated necrotizing myopathy

(2010) Lisa Christopher-Stine et al.   ARTHRITIS AND RHEUMATISM

Autoantibodies against 3-hydroxy-3-methylglutaryl-coenzyme A reductase in patients with statin-associated autoimmune myopathy

(2010) Andrew L. Mammen et al.   ARTHRITIS AND RHEUMATISM

Toll-like receptor 4 mediates lipopolysaccharide-induced muscle catabolism via coordinate activation of ubiquitin-proteasome and autophagy-lysosome pathways

(2010) Alexander Doyle et al.   FASEB JOURNAL

TNF-α Induces Macroautophagy and Regulates MHC Class II Expression in Human Skeletal Muscle Cells

(2010) Christian W. Keller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endogenous Inflammatory Molecules Engage Toll-Like Receptors in Cardiovascular Disease

(2010) Mihaela G. Ionita et al.   Journal of Innate Immunity

FOXP3+ T regulatory cells in idiopathic inflammatory myopathies

(2010) Anne Waschbisch et al.   JOURNAL OF NEUROIMMUNOLOGY

Permissive environment for B-cell maturation in myositis muscle in the absence of B-cell follicles

(2010) Mohammad Salajegheh et al.   MUSCLE & NERVE

Myofiber stress-response in myositis: parallel investigations on patients and experimental animal models of muscle regeneration and systemic inflammation

(2010) Maurizio Vitadello et al.   ARTHRITIS RESEARCH & THERAPY

Overexpression of MHC Class I Heavy Chain Protein in Young Skeletal Muscle Leads to Severe Myositis

(2009) Charles Kwok-chong Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Distribution of the NF-κB Complex in the Inflammatory Exudates Characterizing the Idiopathic Inflammatory Myopathies

(2009) Kim K. Creus et al.   Annals of the New York Academy of Sciences

Dermatomyositis and polymyositis

(2009) Andrew L. Mammen   Annals of the New York Academy of Sciences

Autoantibodies to a 140-kd protein in juvenile dermatomyositis are associated with calcinosis

(2009) H. Gunawardena et al.   ARTHRITIS AND RHEUMATISM

The role of resistin as a regulator of inflammation: Implications for various human pathologies

(2009) Mária Filková et al.   CLINICAL IMMUNOLOGY

Expression of TLR2, TLR4, and TLR9 in dermatomyositis and polymyositis

(2009) Geun-Tae Kim et al.   CLINICAL RHEUMATOLOGY

Th1 and Th17 balance in inflammatory myopathies: Interaction with dendritic cells and possible link with response to high-dose immunoglobulins

(2009) Anne Tournadre et al.   CYTOKINE

Effects of HMGB1 on in vitro responses of isolated muscle fibers and functional aspects in skeletal muscles of idiopathic inflammatory myopathies

(2009) Cecilia Grundtman et al.   FASEB JOURNAL

NLRP3/Cryopyrin Is Necessary for Interleukin-1β (IL-1β) Release in Response to Hyaluronan, an Endogenous Trigger of Inflammation in Response to Injury

(2009) Kenshi Yamasaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cutting Edge: Cardiac Myosin Activates Innate Immune Responses through TLRs

(2009) P. Zhang et al.   JOURNAL OF IMMUNOLOGY

Differential Role for c-Rel and C/EBP /  in TLR-Mediated Induction of Proinflammatory Cytokines

(2009) Y.-C. Lu et al.   JOURNAL OF IMMUNOLOGY

T Cell Infiltrates in the Muscles of Patients with Dermatomyositis and Polymyositis Are Dominated by CD28null T Cells

(2009) A. E. R. Fasth et al.   JOURNAL OF IMMUNOLOGY

Molecular mechanisms involved in inflammasome activation

(2009) Clare Bryant et al.   TRENDS IN CELL BIOLOGY

LPS/TLR4 signal transduction pathway

(2008) Yong-Chen Lu et al.   CYTOKINE

TNF-α acts via TNFR1 and muscle-derived oxidants to depress myofibrillar force in murine skeletal muscle

(2008) Brian J. Hardin et al.   JOURNAL OF APPLIED PHYSIOLOGY

IKK/NF-κB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis

(2008) Nadine Bakkar et al.   JOURNAL OF CELL BIOLOGY

Inflammatory myopathies with mitochondrial pathology and protein aggregates

(2008) Peyker Temiz et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES