Pathogenesis, classification and treatment of inflammatory myopathies

Impaired Autophagy in Sporadic Inclusion-Body Myositis and in Endoplasmic Reticulum Stress-Provoked Cultured Human Muscle Fibers

(2010) Anna Nogalska et al.   AMERICAN JOURNAL OF PATHOLOGY

Expanded T cell receptor Vβ-restricted T cells from patients with sporadic inclusion body myositis are proinflammatory and cytotoxic CD28null T cells

(2010) Jayesh M. Pandya et al.   ARTHRITIS AND RHEUMATISM

A novel autoantibody recognizing 200-kd and 100-kd proteins is associated with an immune-mediated necrotizing myopathy

(2010) Lisa Christopher-Stine et al.   ARTHRITIS AND RHEUMATISM

The role of HMGB1 in the pathogenesis of rheumatic disease

(2010) Ulf Andersson et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

FOXP3+ T regulatory cells in idiopathic inflammatory myopathies

(2010) Anne Waschbisch et al.   JOURNAL OF NEUROIMMUNOLOGY

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(2010) Gustavo Nader et al.   MOLECULAR MEDICINE

Immunotherapy of myositis: issues, concerns and future prospects

(2010) Marinos C. Dalakas   Nature Reviews Rheumatology

Microvasculopathic neuromuscular diseases: Lessons from hypoxia-inducible factors

(2010) Stefan Probst-Cousin et al.   NEUROMUSCULAR DISORDERS

Idiopathic inflammatory myopathies, signified by distinctive peripheral cytokines, chemokines and the TNF family members B-cell activating factor and a proliferation inducing ligand

(2010) P. Szodoray et al.   RHEUMATOLOGY

Overexpression of MHC Class I Heavy Chain Protein in Young Skeletal Muscle Leads to Severe Myositis

(2009) Charles Kwok-chong Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Sera from anti-Jo-1-positive patients with polymyositis and interstitial lung disease induce expression of intercellular adhesion molecule 1 in human lung endothelial cells

(2009) Sevim Barbasso Helmers et al.   ARTHRITIS AND RHEUMATISM

Expression of the dermatomyositis autoantigen Mi-2 in regenerating muscle

(2009) Andrew L. Mammen et al.   ARTHRITIS AND RHEUMATISM

RNA helicase encoded by melanoma differentiation-associated gene 5 is a major autoantigen in patients with clinically amyopathic dermatomyositis: Association with rapidly progressive interstitial lung disease

(2009) Shinji Sato et al.   ARTHRITIS AND RHEUMATISM

Inclusion Body Myositis: A Degenerative Muscle Disease Associated with Intra-Muscle Fiber Multi-Protein Aggregates, Proteasome Inhibition, Endoplasmic Reticulum Stress and Decreased Lysosomal Degradation

(2009) Valerie Askanas et al.   BRAIN PATHOLOGY

Endoplasmic reticulum stress in disease: mechanisms and therapeutic opportunities

(2009) Toru Hosoi et al.   CLINICAL SCIENCE

Exercise effects in patients with adult idiopathic inflammatory myopathies

(2009) Helene Alexanderson   CURRENT OPINION IN RHEUMATOLOGY

Nonimmune mechanisms of muscle damage in myositis: role of the endoplasmic reticulum stress response and autophagy in the disease pathogenesis

(2009) Andrea Henriques-Pons et al.   CURRENT OPINION IN RHEUMATOLOGY

Activating NK-cell receptors co-stimulate CD4+CD28−T cells in patients with rheumatoid arthritis

(2009) Andreas E. R. Fasth et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Effects of HMGB1 on in vitro responses of isolated muscle fibers and functional aspects in skeletal muscles of idiopathic inflammatory myopathies

(2009) Cecilia Grundtman et al.   FASEB JOURNAL

Treatment of Adult Inflammatory Myositis With Rituximab

(2009) Shefali Majmudar et al.   JCR-JOURNAL OF CLINICAL RHEUMATOLOGY

T Cell Infiltrates in the Muscles of Patients with Dermatomyositis and Polymyositis Are Dominated by CD28null T Cells

(2009) A. E. R. Fasth et al.   JOURNAL OF IMMUNOLOGY

Upregulation of MHC class I in transgenic mice results in reduced force-generating capacity in slow-twitch muscle

(2009) Stina Salomonsson et al.   MUSCLE & NERVE

Rituximab in life threatening antisynthetase syndrome

(2009) E. Vandenbroucke et al.   RHEUMATOLOGY INTERNATIONAL

The inflammatory milieu in idiopathic inflammatory myositis

(2009) Ann M. Reed et al.   Current Rheumatology Reports

A high incidence of disease flares in an open pilot study of infliximab in patients with refractory inflammatory myopathies

(2008) M Dastmalchi et al.   ANNALS OF THE RHEUMATIC DISEASES

Increased serum levels of B cell activating factor (BAFF) in subsets of patients with idiopathic inflammatory myopathies

(2008) O Krystufkova et al.   ANNALS OF THE RHEUMATIC DISEASES

Extracellular high mobility group box chromosomal protein 1 is a coupling factor for hypoxia and inflammation in arthritis

(2008) Takashi Hamada et al.   ARTHRITIS AND RHEUMATISM

Vascular endothelial growth factor is highly expressed in muscle tissue of patients with polymyositis and patients with dermatomyositis

(2008) Cecilia Grundtman et al.   ARTHRITIS AND RHEUMATISM

Quantification and molecular characterization of regulatory T cells in connective tissue diseases

(2008) Leontina Banica et al.   AUTOIMMUNITY

The possible role of physical exercise on the treatment of idiopathic inflammatory myopathies

(2008) Vitor de Salles Painelli et al.   AUTOIMMUNITY REVIEWS

Interleukin-6 Is an Essential Regulator of Satellite Cell-Mediated Skeletal Muscle Hypertrophy

(2008) Antonio L. Serrano et al.   Cell Metabolism

Dendritic cells and the immunopathogenesis of idiopathic inflammatory myopathies

(2008) Consuelo M López de Padilla et al.   CURRENT OPINION IN RHEUMATOLOGY

Polymyositis and pemphigus vulgaris in a patient: Successful treatment with rituximab

(2008) Anne Tournadre et al.   JOINT BONE SPINE

Antisynthetase syndrome with refractory polyarthritis and fever successfully treated with the IL-1 receptor antagonist, anakinra: A case report

(2008) Antonio Furlan et al.   JOINT BONE SPINE

Inflammatory myopathies with mitochondrial pathology and protein aggregates

(2008) Peyker Temiz et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Induction and effector functions of TH17 cells

(2008) Estelle Bettelli et al.   NATURE

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

(2008) Inki Kim et al.   NATURE REVIEWS DRUG DISCOVERY

Amyloid-β protein impairs Ca2+ release and contractility in skeletal muscle

(2008) Alexander Shtifman et al.   NEUROBIOLOGY OF AGING

The ER-Bound RING Finger Protein 5 (RNF5/RMA1) Causes Degenerative Myopathy in Transgenic Mice and Is Deregulated in Inclusion Body Myositis

(2008) Agnès Delaunay et al.   PLoS One

Plasmacytoid dendritic cells are present in cutaneous dermatomyositis lesions in a pattern distinct from lupus erythematosus

(2007) Jennifer M. McNiff et al.   JOURNAL OF CUTANEOUS PATHOLOGY