The small leucine-rich repeat proteoglycans in tissue repair and atherosclerosis

Increased atherosclerosis in mice with increased vascular biglycan content

(2014) Joel C. Thompson et al.   ATHEROSCLEROSIS

Decorin and biglycan retain LDL in disease-prone valvular and aortic subendothelial intimal matrix

(2014) Edward B. Neufeld et al.   ATHEROSCLEROSIS

Mechanisms of Plaque Formation and Rupture

(2014) Jacob Fog Bentzon et al.   CIRCULATION RESEARCH

Collagen and related extracellular matrix proteins in atherosclerotic plaque development

(2014) Annelie Shami et al.   CURRENT OPINION IN LIPIDOLOGY

Fibromodulin and Biglycan Modulate Periodontium through TGFβ/BMP Signaling

(2014) L. Wang et al.   JOURNAL OF DENTAL RESEARCH

Complement Inhibitor C4b-Binding Protein Interacts Directly with Small Glycoproteins of the Extracellular Matrix

(2014) K. E. Happonen et al.   JOURNAL OF IMMUNOLOGY

Biglycan deficiency: Increased aortic aneurysm formation and lack of atheroprotection

(2014) Tao Tang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Meta-Analysis of the Association between Lumican Gene Polymorphisms and Susceptibility to High Myopia

(2014) Miao He et al.   PLoS One

Absence of fibromodulin affects matrix composition, collagen deposition and cell turnover in healthy and fibrotic lung parenchyma

(2014) Kristina Rydell-Törmänen et al.   Scientific Reports

Fibromodulin promoted in vitro and in vivo angiogenesis

(2013) Jia Jian et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lumican is increased in experimental and clinical heart failure, and its production by cardiac fibroblasts is induced by mechanical and proinflammatory stimuli

(2013) Kristin V. T. Engebretsen et al.   FEBS Journal

The regulatory roles of small leucine-rich proteoglycans in extracellular matrix assembly

(2013) Shoujun Chen et al.   FEBS Journal

Biological interplay between proteoglycans and their innate immune receptors in inflammation

(2013) Helena Frey et al.   FEBS Journal

Proline/arginine-rich end leucine-rich repeat protein N-terminus is a novel osteoclast antagonist that counteracts bone loss

(2013) Nadia Rucci et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment

(2013) Irit Adini et al.   JOURNAL OF CLINICAL INVESTIGATION

Decorin deficiency promotes hepatic carcinogenesis

(2013) Zsolt Horváth et al.   MATRIX BIOLOGY

Extracellular Matrix Protein Lumican Promotes Clearance and Resolution of Pseudomonas aeruginosa Keratitis in a Mouse Model

(2013) Hanjuan Shao et al.   PLoS One

Decorin causes autophagy in endothelial cells via Peg3

(2013) S. Buraschi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glycosaminoglycan Overproduction in the Aorta Increases Aortic Calcification in Murine Chronic Kidney Disease

(2013) Eko Purnomo et al.   Journal of the American Heart Association

Decorin

(2012) Thomas Neill et al.   AMERICAN JOURNAL OF PATHOLOGY

Fibromodulin Deficiency Reduces Low-Density Lipoprotein Accumulation in Atherosclerotic Plaques in Apolipoprotein E–Null Mice

(2012) Annelie Shami et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Reprogramming of human fibroblasts into multipotent cells with a single ECM proteoglycan, fibromodulin

(2012) Zhong Zheng et al.   BIOMATERIALS

Assessment of Gene Expression Profiles in Peripheral Occlusive Arterial Disease

(2012) Serban Bubenek et al.   CANADIAN JOURNAL OF CARDIOLOGY

Small leucine-rich proteoglycans orchestrate receptor crosstalk during inflammation

(2012) Kristin Moreth et al.   CELL CYCLE

Small leucine-rich proteoglycans, at the crossroad of cancer growth and inflammation

(2012) Liliana Schaefer et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The galactosaminoglycan-containing decorin and its impact on diseases

(2012) Daniela G Seidler   CURRENT OPINION IN STRUCTURAL BIOLOGY

PRELP Protein Inhibits the Formation of the Complement Membrane Attack Complex

(2012) Kaisa E. Happonen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular Matrix Lumican Promotes Bacterial Phagocytosis, andLum−/−Mice Show IncreasedPseudomonas aeruginosaLung Infection Severity

(2012) HanJuan Shao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decorin–TGFβ Axis in Hepatic Fibrosis and Cirrhosis

(2012) Kornélia Baghy et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Bone health in children and adolescent with Turner syndrome

(2012) Montasser Nadeem et al.   JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM

Proteomic Profile of Human Aortic Stenosis: Insights into the Degenerative Process

(2012) Tatiana Martín-Rojas et al.   JOURNAL OF PROTEOME RESEARCH

Effect of Lumican on the Migration of Human Mesenchymal Stem Cells and Endothelial Progenitor Cells: Involvement of Matrix Metalloproteinase-14

(2012) Mariusz Malinowski et al.   PLoS One

Pathophysiological Mechanisms of Autosomal Dominant Congenital Stromal Corneal Dystrophy

(2011) Shoujun Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

Decorin GAG Synthesis and TGF-β Signaling Mediate Ox-LDL–Induced Mineralization of Human Vascular Smooth Muscle Cells

(2011) Jianyun Yan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Leucine-rich repeat (LRR) proteins: Integrators of pattern recognition and signaling in immunity

(2011) Aylwin Ng et al.   Autophagy

Membrane attack by complement: the assembly and biology of terminal complement complexes

(2011) Cosmin A. Tegla et al.   IMMUNOLOGIC RESEARCH

Extracellular matrix protein lumican regulates inflammation in a mouse model of colitis

(2011) Kristin Lohr et al.   INFLAMMATORY BOWEL DISEASES

Decorin Interacts with Connective Tissue Growth Factor (CTGF)/CCN2 by LRR12 Inhibiting Its Biological Activity

(2011) Cecilia Vial et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role for Decorin in Delayed-Type Hypersensitivity

(2011) D. G. Seidler et al.   JOURNAL OF IMMUNOLOGY

Association Analysis of Polymorphisms in Lumican Gene and Systemic Lupus Erythematosus in a Taiwan Chinese Han Population

(2011) P.-C. CHANG et al.   JOURNAL OF RHEUMATOLOGY

Small Leucine-Rich Proteoglycans in Kidney Disease

(2011) L. Schaefer   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Retention of atherogenic lipoproteins in the artery wall and its role in atherogenesis

(2011) P. Fogelstrand et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Signaling by the Matrix Proteoglycan Decorin Controls Inflammation and Cancer Through PDCD4 and MicroRNA-21

(2011) R. Merline et al.   Science Signaling

Lumican inhibits angiogenesis by interfering with α2β1 receptor activity and downregulating MMP-14 expression

(2011) Jolanta Niewiarowska et al.   THROMBOSIS RESEARCH

Lumican inhibits cell migration through α2β1 integrin

(2010) Cédric Zeltz et al.   EXPERIMENTAL CELL RESEARCH

Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans

(2010) Renato V. Iozzo et al.   FEBS Journal

The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis

(2010) Kristin Moreth et al.   JOURNAL OF CLINICAL INVESTIGATION

Delayed Wound Closure in Fibromodulin-Deficient Mice Is Associated with Increased TGF-β3 Signaling

(2010) Zhong Zheng et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The role of small leucine-rich proteoglycans in collagen fibrillogenesis

(2010) Sebastian Kalamajski et al.   MATRIX BIOLOGY

Localization of small leucine-rich proteoglycans and transforming growth factor-β in human oral mucosal wound healing

(2010) Dariush Honardoust et al.   WOUND REPAIR AND REGENERATION

Biglycan and Fibromodulin Have Essential Roles in Regulating Chondrogenesis and Extracellular Matrix Turnover in Temporomandibular Joint Osteoarthritis

(2009) Mildred C. Embree et al.   AMERICAN JOURNAL OF PATHOLOGY

LRRCE: a leucine-rich repeat cysteine capping motif unique to the chordate lineage

(2009) Hosil Park et al.   BMC GENOMICS

ApoCIII-Enriched LDL in Type 2 Diabetes Displays Altered Lipid Composition, Increased Susceptibility for Sphingomyelinase, and Increased Binding to Biglycan

(2009) A. Hiukka et al.   DIABETES

Back to basics - how the evolution of the extracellular matrix underpinned vertebrate evolution

(2009) Julie Huxley-Jones et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Extracellular Matrix Lumican Deposited on the Surface of Neutrophils Promotes Migration by Binding to β2Integrin

(2009) Seakwoo Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic Evidence for the Coordinated Regulation of Collagen Fibrillogenesis in the Cornea by Decorin and Biglycan

(2009) Guiyun Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biglycan, a Danger Signal That Activates the NLRP3 Inflammasome via Toll-like and P2X Receptors

(2009) Andrea Babelova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The glycosaminoglycan-binding domain of PRELP acts as a cell type–specific NF-κB inhibitor that impairs osteoclastogenesis

(2009) Nadia Rucci et al.   JOURNAL OF CELL BIOLOGY

Accelerated arterial stiffening and gene expression profile of the aorta in patients with coronary artery disease

(2009) Céline Fassot et al.   JOURNAL OF HYPERTENSION

Decorin Core Protein (Decoron) Shape Complements Collagen Fibril Surface Structure and Mediates Its Binding

(2009) Joseph P. R. O. Orgel et al.   PLoS One

The matricellular functions of small leucine-rich proteoglycans (SLRPs)

(2009) Rosetta Merline et al.   Journal of Cell Communication and Signaling

Acid Sphingomyelinase Promotes Lipoprotein Retention Within Early Atheromata and Accelerates Lesion Progression

(2008) Cecilia M. Devlin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Early atherosclerosis in humans: role of diffuse intimal thickening and extracellular matrix proteoglycans

(2008) Y. Nakashima et al.   CARDIOVASCULAR RESEARCH

Heparan Sulfate in Perlecan Promotes Mouse Atherosclerosis

(2008) Karin Tran-Lundmark et al.   CIRCULATION RESEARCH

Homologous Sequence in Lumican and Fibromodulin Leucine-rich Repeat 5-7 Competes for Collagen Binding

(2008) Sebastian Kalamajski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biological Functions of the Small Leucine-rich Proteoglycans: From Genetics to Signal Transduction

(2008) Liliana Schaefer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel regulatory mechanisms for the proteoglycans decorin and biglycan during muscle formation and muscular dystrophy

(2008) Enrique Brandan et al.   MATRIX BIOLOGY

Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation

(2008) Andreas P. Sjöberg et al.   MOLECULAR IMMUNOLOGY