Increased mitochondrial ATP production capacity in brain of healthy mice and a mouse model of isolated complex I deficiency after isoflurane anesthesia

2-Deoxy-D-Glucose Enhances Anesthetic Effects in Mice

(2015) Hui Wang et al.   ANESTHESIA AND ANALGESIA

Mitochondrial complex I deficiency leads to inflammation and retinal ganglion cell death in the Ndufs4 mouse

(2015) Alfred K. Yu et al.   HUMAN MOLECULAR GENETICS

Isoflurane anesthetic hypersensitivity and progressive respiratory depression in a mouse model with isolated mitochondrial complex I deficiency

(2014) Suzanne Roelofs et al.   Journal of Anesthesia

Characterization and Quantification of Isoflurane-Induced Developmental Apoptotic Cell Death in Mouse Cerebral Cortex

(2013) George K. Istaphanous et al.   ANESTHESIA AND ANALGESIA

Early Exposure to General Anesthesia Disturbs Mitochondrial Fission and Fusion in the Developing Rat Brain

(2013) Annalisa Boscolo et al.   ANESTHESIOLOGY

Anesthetic considerations in patients with mitochondrial defects

(2013) Julie Niezgoda et al.   PEDIATRIC ANESTHESIA

Impaired Spatial Learning and Memory after Sevoflurane–Nitrous Oxide Anesthesia in Aged Rats Is Associated with Down-Regulated cAMP/CREB Signaling

(2013) Wan-Xia Xiong et al.   PLoS One

Early Developmental Exposure to Volatile Anesthetics Causes Behavioral Defects in Caenorhabditis elegans

(2012) Katherine R. Gentry et al.   ANESTHESIA AND ANALGESIA

Regional susceptibilities to mitochondrial dysfunctions in the CNS

(2012) Milena Pinto et al.   BIOLOGICAL CHEMISTRY

OXPHOS mutations and neurodegeneration

(2012) Werner J H Koopman et al.   EMBO JOURNAL

Proteomic and Metabolomic Analyses of Mitochondrial Complex I-deficient Mouse Model Generated by Spontaneous B2 Short Interspersed Nuclear Element (SINE) Insertion into NADH Dehydrogenase (Ubiquinone) Fe-S Protein 4 (Ndufs4) Gene

(2012) Dillon W. Leong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fatal breathing dysfunction in a mouse model of Leigh syndrome

(2012) Albert Quintana et al.   JOURNAL OF CLINICAL INVESTIGATION

Altered Anesthetic Sensitivity of Mice Lacking Ndufs4, a Subunit of Mitochondrial Complex I

(2012) Albert Quintana et al.   PLoS One

Isoflurane Selectively Inhibits Distal Mitochondrial Complex I in Caenorhabditis Elegans

(2011) Ernst-Bernhard Kayser et al.   ANESTHESIA AND ANALGESIA

Comparison of the Neuroapoptotic Properties of Equipotent Anesthetic Concentrations of Desflurane, Isoflurane, or Sevoflurane in Neonatal Mice

(2011) George K. Istaphanous et al.   ANESTHESIOLOGY

Newly Postulated Neurodevelopmental Risks of Pediatric Anesthesia

(2011) Stephen R. Hays et al.   Current Neurology and Neuroscience Reports

Mitochondrial complex III stabilizes complex I in the absence of NDUFS4 to provide partial activity

(2011) M. A. Calvaruso et al.   HUMAN MOLECULAR GENETICS

Biochemical diagnosis of mitochondrial disorders

(2010) Richard J. T. Rodenburg   JOURNAL OF INHERITED METABOLIC DISEASE

Complex I deficiency due to loss of Ndufs4 in the brain results in progressive encephalopathy resembling Leigh syndrome

(2010) A. Quintana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Assessment of the Effects of General Anesthetics on Developing Brain Structure and Neurocognitive Function

(2008) Andreas W. Loepke et al.   ANESTHESIA AND ANALGESIA

Mice with Mitochondrial Complex I Deficiency Develop a Fatal Encephalomyopathy

(2008) Shane E. Kruse et al.   Cell Metabolism