Connecting up and clearing out: how kinetochore attachment silences the spindle assembly checkpoint

Phosphodependent Recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 Kinase Maintains the Spindle Checkpoint

(2012) Lindsey A. Shepperd et al.   CURRENT BIOLOGY

Phosphoregulation of Spc105 by Mps1 and PP1 Regulates Bub1 Localization to Kinetochores

(2012) Nitobe London et al.   CURRENT BIOLOGY

A conserved role for COMA/CENP-H/I/N kinetochore proteins in the spindle checkpoint

(2012) D. R. Matson et al.   GENES & DEVELOPMENT

Aurora B controls kinetochore–microtubule attachments by inhibiting Ska complex–KMN network interaction

(2012) Ying Wai Chan et al.   JOURNAL OF CELL BIOLOGY

Feedback Control in Sensing Chromosome Biorientation by the Aurora B Kinase

(2011) Kevan J. Salimian et al.   CURRENT BIOLOGY

KNL1/Spc105 Recruits PP1 to Silence the Spindle Assembly Checkpoint

(2011) Jessica S. Rosenberg et al.   CURRENT BIOLOGY

Spindle Checkpoint Silencing Requires Association of PP1 to Both Spc7 and Kinesin-8 Motors

(2011) John C. Meadows et al.   DEVELOPMENTAL CELL

Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction

(2011) Stefano Santaguida et al.   EMBO JOURNAL

The astrin–kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment

(2011) Anja K. Dunsch et al.   JOURNAL OF CELL BIOLOGY

A mitotic role for Mad1 beyond the spindle checkpoint

(2011) D. Emre et al.   JOURNAL OF CELL SCIENCE

BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner

(2011) Pablo Lara-Gonzalez et al.   JOURNAL OF CELL SCIENCE

Temporal changes in Hec1 phosphorylation control kinetochore-microtubule attachment stability during mitosis

(2011) K. F. DeLuca et al.   JOURNAL OF CELL SCIENCE

Protein Interaction Domain Mapping of Human Kinetochore Protein Blinkin Reveals a Consensus Motif for Binding of Spindle Assembly Checkpoint Proteins Bub1 and BubR1

(2011) T. Kiyomitsu et al.   MOLECULAR AND CELLULAR BIOLOGY

Zwint-1 is a novel Aurora B substrate required for the assembly of a dynein-binding platform on kinetochores

(2011) James M. Kasuboski et al.   MOLECULAR BIOLOGY OF THE CELL

Defining pathways of spindle checkpoint silencing: functional redundancy between Cdc20 ubiquitination and p31comet

(2011) Luying Jia et al.   MOLECULAR BIOLOGY OF THE CELL

p31comet acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachment

(2011) Robert S. Hagan et al.   MOLECULAR BIOLOGY OF THE CELL

Homeostatic Control of Mitotic Arrest

(2011) Gianluca Varetti et al.   MOLECULAR CELL

Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase

(2011) Emily A. Foley et al.   NATURE CELL BIOLOGY

Constitutive Mad1 targeting to kinetochores uncouples checkpoint signalling from chromosome biorientation

(2011) Maria Maldonado et al.   NATURE CELL BIOLOGY

Dynein/Dynactin-Mediated Transport of Kinetochore Components off Kinetochores and onto Spindle Poles Induced by Nordihydroguaiaretic Acid

(2011) Jakub K. Famulski et al.   PLoS One

p31comet promotes disassembly of the mitotic checkpoint complex in an ATP-dependent process

(2011) A. Teichner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic Phosphorylation Analysis of Human Mitotic Protein Complexes

(2011) B. Hegemann et al.   Science Signaling

Spatial Exclusivity Combined with Positive and Negative Selection of Phosphorylation Motifs Is the Basis for Context-Dependent Mitotic Signaling

(2011) J. Alexander et al.   Science Signaling

Quantitative Phosphoproteomics Identifies Substrates and Functional Modules of Aurora and Polo-Like Kinase Activities in Mitotic Cells

(2011) A. N. Kettenbach et al.   Science Signaling

Mitotic Substrates of the Kinase Aurora with Roles in Chromatin Regulation Identified Through Quantitative Phosphoproteomics of Fission Yeast

(2011) A. Koch et al.   Science Signaling

Mutual regulation between the spindle checkpoint and APC/C

(2011) Soonjoung Kim et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site

(2011) Victor M. Bolanos-Garcia et al.   STRUCTURE

Aurora B potentiates Mps1 activation to ensure rapid checkpoint establishment at the onset of mitosis

(2011) Adrian T. Saurin et al.   Nature Communications

CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity

(2010) Amity L Manning et al.   EMBO JOURNAL

Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells

(2010) R. Gassmann et al.   GENES & DEVELOPMENT

Sds22 regulates aurora B activity and microtubule–kinetochore interactions at mitosis

(2010) Markus Posch et al.   JOURNAL OF CELL BIOLOGY

Mps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling

(2010) John Maciejowski et al.   JOURNAL OF CELL BIOLOGY

Release of Mps1 from kinetochores is crucial for timely anaphase onset

(2010) Nannette Jelluma et al.   JOURNAL OF CELL BIOLOGY

Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase

(2010) Dan Liu et al.   JOURNAL OF CELL BIOLOGY

Aurora B kinase controls the targeting of the Astrin–SKAP complex to bioriented kinetochores

(2010) Jens C. Schmidt et al.   JOURNAL OF CELL BIOLOGY

Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine

(2010) Stefano Santaguida et al.   JOURNAL OF CELL BIOLOGY

Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1–C-Mad2 core complex

(2010) Laura Hewitt et al.   JOURNAL OF CELL BIOLOGY

APC16 is a conserved subunit of the anaphase-promoting complex/cyclosome

(2010) G. J. P. L. Kops et al.   JOURNAL OF CELL SCIENCE

Welcome to a new kind of tension: translating kinetochore mechanics into a wait-anaphase signal

(2010) Thomas J. Maresca et al.   JOURNAL OF CELL SCIENCE

Sgo1 establishes the centromeric cohesion protection mechanism in G2 before subsequent Bub1-dependent recruitment in mitosis

(2010) D. Perera et al.   JOURNAL OF CELL SCIENCE

Spindly/CCDC99 Is Required for Efficient Chromosome Congression and Mitotic Checkpoint Regulation

(2010) Marin Barisic et al.   MOLECULAR BIOLOGY OF THE CELL

Aurora B Phosphorylates Spatially Distinct Targets to Differentially Regulate the Kinetochore-Microtubule Interface

(2010) Julie P.I. Welburn et al.   MOLECULAR CELL

Molecular control of kinetochore-microtubule dynamics and chromosome oscillations

(2010) Ana C. Amaro et al.   NATURE CELL BIOLOGY

Centromere tension: a divisive issue

(2010) Alexey Khodjakov et al.   NATURE CELL BIOLOGY

Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function

(2010) Nicholas Kwiatkowski et al.   Nature Chemical Biology

Chemical Genetic Inhibition of Mps1 in Stable Human Cell Lines Reveals Novel Aspects of Mps1 Function in Mitosis

(2010) Tale Sliedrecht et al.   PLoS One

Sensing centromere tension: Aurora B and the regulation of kinetochore function

(2010) Michael A. Lampson et al.   TRENDS IN CELL BIOLOGY

Protein Architecture of the Human Kinetochore Microtubule Attachment Site

(2009) Xiaohu Wan et al.   CELL

Ska3 Is Required for Spindle Checkpoint Silencing and the Maintenance of Chromosome Cohesion in Mitosis

(2009) John R. Daum et al.   CURRENT BIOLOGY

Protein Phosphatase 1 Regulates Exit from the Spindle Checkpoint in Budding Yeast

(2009) Benjamin A. Pinsky et al.   CURRENT BIOLOGY

A Novel Protein Phosphatase 1-Dependent Spindle Checkpoint Silencing Mechanism

(2009) Vincent Vanoosthuyse et al.   CURRENT BIOLOGY

Correcting aberrant kinetochore microtubule attachments: an Aurora B-centric view

(2009) Alexander E Kelly et al.   CURRENT OPINION IN CELL BIOLOGY

Sister chromatid tension and the spindle assembly checkpoint

(2009) Luigi Nezi et al.   CURRENT OPINION IN CELL BIOLOGY

Unattached Kinetochores Catalyze Production of an Anaphase Inhibitor that Requires a Mad2 Template to Prime Cdc20 for BubR1 Binding

(2009) Anita Kulukian et al.   DEVELOPMENTAL CELL

A quantitative systems view of the spindle assembly checkpoint

(2009) Andrea Ciliberto et al.   EMBO JOURNAL

Mimicking Ndc80 phosphorylation triggers spindle assembly checkpoint signalling

(2009) Stefan Kemmler et al.   EMBO JOURNAL

Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division

(2009) Mirko Theis et al.   EMBO JOURNAL

Kinetochore stretching inactivates the spindle assembly checkpoint

(2009) Kazuhiko S.K. Uchida et al.   JOURNAL OF CELL BIOLOGY

Intrakinetochore stretch is associated with changes in kinetochore phosphorylation and spindle assembly checkpoint activity

(2009) Thomas J. Maresca et al.   JOURNAL OF CELL BIOLOGY

Bub1 regulates chromosome segregation in a kinetochore-independent manner

(2009) Christiane Klebig et al.   JOURNAL OF CELL BIOLOGY

Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly

(2009) Ying Wai Chan et al.   JOURNAL OF CELL BIOLOGY

RAMA1 is a novel kinetochore protein involved in kinetochore-microtubule attachment

(2009) J. A. Raaijmakers et al.   JOURNAL OF CELL SCIENCE

Sensing Chromosome Bi-Orientation by Spatial Separation of Aurora B Kinase from Kinetochore Substrates

(2009) D. Liu et al.   SCIENCE

The Influence of Catalysis on Mad2 Activation Dynamics

(2009) Marco Simonetta et al.   PLOS BIOLOGY

Mps1 Phosphorylates Borealin to Control Aurora B Activity and Chromosome Alignment

(2008) Nannette Jelluma et al.   CELL

Cyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosis

(2008) Qiang Chen et al.   CELL RESEARCH

Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly

(2008) Marvin E Tanenbaum et al.   EMBO JOURNAL

A new mechanism controlling kinetochore-microtubule interactions revealed by comparison of two dynein-targeting components: SPDL-1 and the Rod/Zwilch/Zw10 complex

(2008) R. Gassmann et al.   GENES & DEVELOPMENT

Phosphorylation regulates targeting of cytoplasmic dynein to kinetochores during mitosis

(2008) Jacqueline Whyte et al.   JOURNAL OF CELL BIOLOGY

Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly

(2008) Michael J. Emanuele et al.   JOURNAL OF CELL BIOLOGY

SPDL-1 functions as a kinetochore receptor for MDF-1 inCaenorhabditis elegans

(2008) Takaharu G. Yamamoto et al.   JOURNAL OF CELL BIOLOGY

The Human Spindle Assembly Checkpoint Protein Bub3 Is Required for the Establishment of Efficient Kinetochore–Microtubule Attachments

(2008) Elsa Logarinho et al.   MOLECULAR BIOLOGY OF THE CELL

Protein Metamorphosis: The Two-State Behavior of Mad2

(2008) Xuelian Luo et al.   STRUCTURE