Defining pathways of spindle checkpoint silencing: functional redundancy between Cdc20 ubiquitination and p31comet

Orderly Inactivation of the Key Checkpoint Protein Mitotic Arrest Deficient 2 (MAD2) during Mitotic Progression

(2011) Hoi Tang Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How APC/C–Cdc20 changes its substrate specificity in mitosis

(2011) Daisuke Izawa et al.   NATURE CELL BIOLOGY

p31comet promotes disassembly of the mitotic checkpoint complex in an ATP-dependent process

(2011) A. Teichner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmacologic Inhibition of the Anaphase-Promoting Complex Induces A Spindle Checkpoint-Dependent Mitotic Arrest in the Absence of Spindle Damage

(2010) Xing Zeng et al.   CANCER CELL

Requirement for proteolysis in spindle assembly checkpoint silencing

(2010) Roberta Visconti et al.   CELL CYCLE

Evidence that Mitotic Exit Is a Better Cancer Therapeutic Target Than Spindle Assembly

(2009) Hsiao-Chun Huang et al.   CANCER CELL

Unattached Kinetochores Catalyze Production of an Anaphase Inhibitor that Requires a Mad2 Template to Prime Cdc20 for BubR1 Binding

(2009) Anita Kulukian et al.   DEVELOPMENTAL CELL

Structure of the Anaphase-Promoting Complex/Cyclosome Interacting with a Mitotic Checkpoint Complex

(2009) F. Herzog et al.   SCIENCE

The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction

(2008) Jakob Nilsson et al.   NATURE CELL BIOLOGY

Protein Metamorphosis: The Two-State Behavior of Mad2

(2008) Xuelian Luo et al.   STRUCTURE

Insights into Mad2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric Mad2 Dimer

(2008) Maojun Yang et al.   PLOS BIOLOGY