Constitutive Mad1 targeting to kinetochores uncouples checkpoint signalling from chromosome biorientation

A chemical tool box defines mitotic and interphase roles for Mps1 kinase

(2010) Weijie Lan et al.   JOURNAL OF CELL BIOLOGY

Release of Mps1 from kinetochores is crucial for timely anaphase onset

(2010) Nannette Jelluma et al.   JOURNAL OF CELL BIOLOGY

Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine

(2010) Stefano Santaguida et al.   JOURNAL OF CELL BIOLOGY

Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function

(2010) Nicholas Kwiatkowski et al.   Nature Chemical Biology

Protein Architecture of the Human Kinetochore Microtubule Attachment Site

(2009) Xiaohu Wan et al.   CELL

A Novel Protein Phosphatase 1-Dependent Spindle Checkpoint Silencing Mechanism

(2009) Vincent Vanoosthuyse et al.   CURRENT BIOLOGY

Unattached Kinetochores Catalyze Production of an Anaphase Inhibitor that Requires a Mad2 Template to Prime Cdc20 for BubR1 Binding

(2009) Anita Kulukian et al.   DEVELOPMENTAL CELL

The life and miracles of kinetochores

(2009) Stefano Santaguida et al.   EMBO JOURNAL

Kinase Signaling in the Spindle Checkpoint

(2009) Jungseog Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sensing Chromosome Bi-Orientation by Spatial Separation of Aurora B Kinase from Kinetochore Substrates

(2009) D. Liu et al.   SCIENCE

The Influence of Catalysis on Mad2 Activation Dynamics

(2009) Marco Simonetta et al.   PLOS BIOLOGY

Linking Kinetochore-Microtubule Binding to the Spindle Checkpoint

(2008) Daniel J. Burke et al.   DEVELOPMENTAL CELL

Polo on the Rise—from Mitotic Entry to Cytokinesis with Plk1

(2008) Mark Petronczki et al.   DEVELOPMENTAL CELL

Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly

(2008) Michael J. Emanuele et al.   JOURNAL OF CELL BIOLOGY

Protein Metamorphosis: The Two-State Behavior of Mad2

(2008) Xuelian Luo et al.   STRUCTURE