Macrodiolide Formation by the Thioesterase of a Modular Polyketide Synthase

An Evolutionary Model Encompassing Substrate Specificity and Reactivity of Type I Polyketide Synthase Thioesterases

(2014) Taylor P. A. Hari et al.   CHEMBIOCHEM

ATrans-Acting Ketoreductase in Biosynthesis of a Symmetric Polyketide Dimer SIA7248

(2013) Yi Zou et al.   CHEMBIOCHEM

Thioesterase Domains of Fungal Nonreducing Polyketide Synthases Act as Decision Gates during Combinatorial Biosynthesis

(2013) Yuquan Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Discovery of the Rhizopodin Biosynthetic Gene Cluster in Stigmatella aurantiaca Sg a15 by Genome Mining

(2012) Dominik Pistorius et al.   CHEMBIOCHEM

6-Deoxyerythronolide B Synthase Thioesterase-Catalyzed Macrocyclization Is Highly Stereoselective

(2012) Atahualpa Pinto et al.   ORGANIC LETTERS

Isolation of a novel macrocyclic dilactone—JBIR-101—from Promicromonospora sp. RL26

(2011) Miho Izumikawa et al.   JOURNAL OF ANTIBIOTICS

Terminal Alkene Formation by the Thioesterase of Curacin A Biosynthesis

(2011) Jennifer J. Gehret et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biochemical and Structural Characterization of the Tautomycetin Thioesterase: Analysis of a Stereoselective Polyketide Hydrolase

(2010) Jamie B. Scaglione et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Biosynthetic Logic of Polyketide Diversity

(2009) Christian Hertweck   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Thioesterase from an Iterative Fungal Polyketide Synthase Shows Macrocyclization and Cross Coupling Activity and May Play a Role in Controlling Iterative Cycling through Product Offloading

(2009) Meng Wang et al.   BIOCHEMISTRY

The chemical biology of modular biosynthetic enzymes

(2009) Jordan L. Meier et al.   CHEMICAL SOCIETY REVIEWS

Revisiting the modularity of modular polyketide synthases

(2009) Chaitan Khosla et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

TioS T-TE - a prototypical thioesterase responsible for cyclodimerization of the quinoline- and quinoxaline-type class of chromodepsipeptides

(2009) Lars Robbel et al.   FEBS Journal

PKS and NRPS release mechanisms

(2009) Liangcheng Du et al.   NATURAL PRODUCT REPORTS

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

Evolution of metabolic diversity: Insights from microbial polyketide synthases

(2009) Holger Jenke-Kodama et al.   PHYTOCHEMISTRY