Article
Chemistry, Inorganic & Nuclear
Janusz Gregolinski, Katarzyna Slepokura, Julia Ktak, Maciej Witwicki
Summary: In this study, a series of hexanuclear chloride and sulfate Ni(II) and Cu(II) complexes were successfully synthesized from appropriate metal salts and octadecaaza macrocyclic ligands. The obtained coordination compounds were characterized using various methods, including elemental analysis, spectroscopic methods, magnetic measurements, and X-ray crystallography. The X-ray crystal structures revealed different coordination modes of the metal cations in the obtained coordination compounds. The folding conformation of the macrocyclic ligand depended on the number of metal cations bound within the macrocycle. All Ni(II) and Cu(II) coordination compounds exhibited paramagnetic behavior. The magnetic measurements showed that the magnetic behavior of certain complexes was dominated by the magnetic anisotropy of the metal ion, while others revealed small antiferromagnetic interactions within the metal units. The EPR experiments indicated that the predominant contribution to the orbitals occupied by the unpaired electrons in the ground state originated from d(x2-y2) orbitals.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Applied
Gina Lupascu, Elena Pahontu, Sergiu Shova, Stefania Felicia Barbuceanu, Mihaela Badea, Codruta Paraschivescu, Johny Neamtu, Mihaela Dinu, Robert Viorel Ancuceanu, Doina Draganescu, Cristina Elena Dinu-Pirvu
Summary: The synthesis and characterization of HL and its cobalt, copper, manganese, nickel, palladium, and platinum complexes were investigated using various physico-chemical techniques. The coordination geometries of Ni2+ and Pd2+ were square planar, while that of copper atom was described as tetrahedrally distorted square planar. Toxicity assessment showed that the Mn2+ complex did not exhibit any lethal effect on animal cells.
APPLIED ORGANOMETALLIC CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Priyanka Devi, Kiran Singh, Bhupender Kumar, Jahnavi Kumari Singh
Summary: Many pyrazoles-based Schiff bases were reported to exhibit high activity against bacterial, parasitic strains, and cancer cells. A new pyrazole based 'NO' bidentate ligand was synthesized and metal complexes with Co+2, Ni+2, Cu+2, and Zn+2 were also prepared. The characterization of the compounds and their metal complexes was performed, and the metal complexes showed enhanced activity compared to the ligand. They exhibited significant anticancer and antibacterial activity, as well as antifungal activity.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Gulnur Keser Karaoglan
Summary: In this study, a new series of Schiff base metal complexes were synthesized and characterized. The thermal stability and photophysical properties of these complexes were investigated. The results showed that the metal ions affected the thermal strength and fluorescence quenching constant of the complexes, with the Cu(II) complex exhibiting the highest thermal strength. Due to their high fluorescence quenching constants, these complexes could be potential active ingredients in anticancer drug transport systems.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Physical
Zohreh Alyaninezhad, Ahmadreza Bekhradnia, Reza Zibandeh Gorgi, Zahra Ghanbarimasir, Morteza Fouladpour
Summary: A series of novel metal complexes of 4-aminoantipyrine quinoxaline were synthesized and characterized. The synthesized compounds showed potential inhibitory activity in cancer cell lines.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Inorganic & Nuclear
M. M. El-Zahed, A. Z. El-Sonbati, F. M. S. Ajadain, M. A. Diab, M. I. Abou-Dobara
Summary: In this study, a novel symmetric bis-Schiff base (H2L) was synthesized and its structure was determined using various spectral and physicochemical techniques. The synthesized compounds were found to have octahedral geometry, except for one which had a tetrahedral structure. Additionally, one of the complexes (5) exhibited the highest antibacterial activity among the ligand, complexes, and standard antibiotic.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Chemistry, Applied
Kadtala Venkateswarlu, Sreenu Daravath, Gali Ramesh, P. V. Anantha Lakshmi, Shivaraj
Summary: The synthesis and characterization of novel binary metal complexes were conducted, with results indicating good performance in DNA binding, antioxidation, and antibacterial activity.
APPLIED ORGANOMETALLIC CHEMISTRY
(2021)
Article
Chemistry, Physical
Jiajia Qi, Yun Luo, Qianxi Zhou, Guozhen Su, Xuan Zhang, Xuegang Nie, Mingyue Lv, Wenge Li
Summary: Two metal-organic complexes were synthesized and characterized, and their cytotoxicity and apoptosis properties were investigated.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Physical
Maxwell O. Nwokelo, David C. Izuogu, Obinna C. Okpareke, Collins U. Ibeji, Ebube E. Oyeka, Joseph R. Lane, Jonnie N. Asegbeloyin
Summary: The novel Schiff base compound TB-SHOPA and its metal complexes were synthesized, characterized, and analyzed using various methods. It was found that the Co(II) and Zn(II) metal complexes exhibited better antimicrobial activities.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Biochemistry & Molecular Biology
Mehmet Esref Alkis, Kenan Buldurun, Nevin Turan, Yusuf Alan, Unzile Kelestemur Yilmaz, Asim Mantarci
Summary: In this study, a new Schiff base and its Ni(II) and Pd(II) complexes were synthesized and characterized. The antiproliferative activities of these compounds on liver cancer cells were evaluated, and it was found that the complexes exhibited stronger activity than the ligand. Electroporation was also shown to enhance the cytotoxicity of the complexes. These findings suggest that the Ni(II) and Pd(II) complexes have potential as anti-cancer agents, particularly in electrochemotherapy.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2022)
Article
Chemistry, Applied
Rajani Kanta Mahato, Ananya Debnath, Ajit Das, Debanjan Sarkar, Sankar Bhattacharyya, Bhaskar Biswas
Summary: The study presents a solvent-free green synthesis of two Schiff bases and their inclusion complexes with γ-cyclodextrin, showing inhibitory activity against breast cancer cells and potential in triggering apoptosis.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Multidisciplinary
Min Hou, Hou Cong Li, Ning An, Wen Ge Li, Jing Tong
Summary: Three metal complexes based on 2,3-dihydroxybenzaldehyde-2-(2-aminophenyl)benzimidazole Schiff base were synthesized and characterized. Complex 1 belongs to the monoclinic crystal system, complex 2 belongs to the triclinic crystal system, and complex 3 belongs to the trigonal crystal system. The complexes exhibited excellent anticancer activities, with complex 2 showing significantly better properties than cisplatin against CNE-2Z cells. Additionally, complex 2 was found to inhibit tumor cell proliferation through apoptosis and migration.
ARABIAN JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Physical
Hadi Kargar, Amir Adabi Ardakani, Muhammad Nawaz Tahir, Muhammad Ashfaq, Khurram Shahzad Munawar
Summary: Three new mononuclear metal complexes with Salen-type tetradentate Schiff base ligand have been synthesized and characterized, showing significant antibacterial activities against various bacterial strains. Nickel and copper complexes have monoclinic crystal system, while zinc complex has orthorhombic crystal system, all with specific coordination geometries.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Multidisciplinary
Hanan B. Howsaui, Abeer A. Sharfalddin, Magda H. Abdellattif, Amal S. Basaleh, Mostafa A. Hussien
Summary: Novel anti-cancer transition metal complexes were successfully synthesized and characterized using Schiff base derived from 2-aminopyrazine and salicylaldehyde. The complexes exhibited different structures and properties under different metal ions, showing promising anti-cancer activity. The Cu(II) complex showed practical results with HOP-62 cell lines, while the Zn(II) and Co(II) complexes demonstrated non-toxicity at doses up to 370 mg/kg based on LD50 values.
APPLIED SCIENCES-BASEL
(2021)
Article
Chemistry, Applied
Adel Z. El-Sonbati, Mostafa A. Diab, Ahmed K. El-Sayed, Mohamed Abou-Dobara, Sameh A. El-Sayad
Summary: Metal complexes of a Schiff base ligand derived from 2,4-dihydroxybenzaldehyde and p-nitroaniline were synthesized and characterized. The complexes showed antibacterial, antifungal, and cytotoxic activities, and the ligand exhibited high binding affinity to various receptors.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
