Discovery of Novel Stem Cell Mobilizers That Target the CXCR4 Receptor

The bone marrow microenvironment and leukemia: biology and therapeutic targeting

(2011) Edward Allan R Sison et al.   Expert Review of Hematology

SDF-1:CXCR4 Axis Is Fundamental for Tissue Preservation and Repair

(2010) Marc S. Penn   AMERICAN JOURNAL OF PATHOLOGY

Novel N-substituted benzimidazole CXCR4 antagonists as potential anti-HIV agents

(2010) John F. Miller et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and SAR of novel isoquinoline CXCR4 antagonists with potent anti-HIV activity

(2010) John F. Miller et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of a novel tricyclic 1,2,3,4,4a,5,6,10b-octahydro-1,10-phenanthroline ring system and CXCR4 antagonists with potent activity against HIV-1

(2010) John G. Catalano et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and SAR of novel CXCR4 antagonists that are potent inhibitors of T tropic (X4) HIV-1 replication

(2010) Renato Skerlj et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

CXCR4-CXCL12-Dependent Inflammatory Network and Endothelial Progenitors

(2010) P. Salvatore et al.   CURRENT MEDICINAL CHEMISTRY

Dipyrimidine Amines: A Novel Class of Chemokine Receptor Type 4 Antagonists with High Specificity

(2010) Aizhi Zhu et al.   JOURNAL OF MEDICINAL CHEMISTRY

FDA Review Summary: Mozobil in Combination with Granulocyte Colony-Stimulating Factor to Mobilize Hematopoietic Stem Cells to the Peripheral Blood for Collection and Subsequent Autologous Transplantation

(2010) Michael Brave et al.   ONCOLOGY

Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists

(2010) B. Wu et al.   SCIENCE

Small molecule modulation of stem cells in regenerative medicine: recent applications and future direction

(2010) Timothy E. Allsopp et al.   MedChemComm

Discovery of Quinazolines as Histamine H4Receptor Inverse Agonists Using a Scaffold Hopping Approach

(2008) Rogier A. Smits et al.   JOURNAL OF MEDICINAL CHEMISTRY

Orally Bioavailable Isothioureas Block Function of the Chemokine Receptor CXCR4 In Vitro and In Vivo

(2008) Gebhard Thoma et al.   JOURNAL OF MEDICINAL CHEMISTRY

Introduction of Functional Groups into Peptides viaN-Alkylation

(2008) O. Demmer et al.   ORGANIC LETTERS