The bone marrow microenvironment and leukemia: biology and therapeutic targeting
Published 2011 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The bone marrow microenvironment and leukemia: biology and therapeutic targeting
Authors
Keywords
-
Journal
Expert Review of Hematology
Volume 4, Issue 3, Pages 271-283
Publisher
Informa UK Limited
Online
2011-06-15
DOI
10.1586/ehm.11.30
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Pan-histone deacetylase inhibitor panobinostat depletes CXCR4 levels and signaling and exerts synergistic antimyeloid activity in combination with CXCR4 antagonists
- (2010) A. Mandawat et al. BLOOD
- How I treat Philadelphia chromosome-positive acute lymphoblastic leukemia
- (2010) A. K. Fielding BLOOD
- The microenvironment differentially impairs passive and active immunotherapy in chronic lymphocytic leukaemia - CXCR4 antagonists as potential adjuvants for monoclonal antibodies
- (2010) Maike Buchner et al. BRITISH JOURNAL OF HAEMATOLOGY
- CXCL12 / CXCR4 / CXCR7 chemokine axis and cancer progression
- (2010) Xueqing Sun et al. CANCER AND METASTASIS REVIEWS
- CXCR7: a new SDF-1-binding receptor in contrast to normal CD34+ progenitors is functional and is expressed at higher level in human malignant hematopoietic cells
- (2010) Maciej Tarnowski et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis, down-regulates the CXCR4 chemokine receptor and impairs migration of chronic lymphocytic leukemia cells
- (2010) B. Stamatopoulos et al. HAEMATOLOGICA
- Bone marrow mesenchymal stromal cells non-selectively protect chronic myeloid leukemia cells from imatinib-induced apoptosis via the CXCR4/CXCL12 axis
- (2010) F. Vianello et al. HAEMATOLOGICA
- High Expression of the Very Late Antigen-4 Integrin Independently Predicts Reduced Risk of Relapse and Improved Outcome in Pediatric Acute Myeloid Leukemia: A Report From the Children's Oncology Group
- (2010) Roland B. Walter et al. JOURNAL OF CLINICAL ONCOLOGY
- Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
- (2010) Marc H. G. P. Raaijmakers et al. NATURE
- Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
- (2010) Simón Méndez-Ferrer et al. NATURE
- Can inhibition of the SDF-1/CXCR4 axis eradicate acute leukemia?
- (2010) Sigal Tavor et al. SEMINARS IN CANCER BIOLOGY
- Pharmacology of AMD3465: A small molecule antagonist of the chemokine receptor CXCR4
- (2009) Veronique Bodart et al. BIOCHEMICAL PHARMACOLOGY
- Kinetics of normal hematopoietic stem and progenitor cells in a Notch1-induced leukemia model
- (2009) X. Hu et al. BLOOD
- CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling
- (2009) A. Levoye et al. BLOOD
- The role of stromal-derived factor-1 — CXCR7 axis in development and cancer
- (2009) Radoslaw B. Maksym et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Impact of CXCR4 inhibition on FLT3-ITD−positive human AML blasts
- (2009) Angela Jacobi et al. EXPERIMENTAL HEMATOLOGY
- Phase III Prospective Randomized Double-Blind Placebo-Controlled Trial of Plerixafor Plus Granulocyte Colony-Stimulating Factor Compared With Placebo Plus Granulocyte Colony-Stimulating Factor for Autologous Stem-Cell Mobilization and Transplantation for Patients With Non-Hodgkin's Lymphoma
- (2009) John F. DiPersio et al. JOURNAL OF CLINICAL ONCOLOGY
- Vasculogenic mimicry of acute leukemic bone marrow stromal cells
- (2009) P Mirshahi et al. LEUKEMIA
- Contribution of bone microenvironment to leukemogenesis and leukemia progression
- (2009) F Ayala et al. LEUKEMIA
- The CXCR4 antagonist 4F-benzoyl-TN14003 stimulates the recovery of the bone marrow after transplantation
- (2009) M Abraham et al. LEUKEMIA
- Plerixafor inhibits chemotaxis toward SDF-1 and CXCR4-mediated stroma contact in a dose-dependent manner resulting in increased susceptibility of BCR-ABL+cell to Imatinib and Nilotinib
- (2009) Falk Dillmann et al. LEUKEMIA & LYMPHOMA
- Valproic acid exerts differential effects on CXCR4 expression in leukemic cells
- (2009) Hilal Gul et al. LEUKEMIA RESEARCH
- Concurrent Blockade of α4-Integrin and CXCR4 in Hematopoietic Stem/Progenitor Cell Mobilization
- (2009) Halvard Bonig et al. STEM CELLS
- BCR-ABL1 alters SDF-1 -mediated adhesive responses through the 2 integrin LFA-1 in leukemia cells
- (2008) Y.-Y. Chen et al. BLOOD
- Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML
- (2008) Z. Zeng et al. BLOOD
- Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100
- (2008) B. Nervi et al. BLOOD
- Bone marrow stromal cells and the upregulation of interleukin-8 production in human T-cell acute lymphoblastic leukemia through the CXCL12/CXCR4 axis and the NF- B and JNK/AP-1 pathways
- (2008) M. T. Scupoli et al. HAEMATOLOGICA
- CXCR4 is required for the quiescence of primitive hematopoietic cells
- (2008) Yuchun Nie et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells
- (2008) Tanja Nicole Hartmann et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Combining SDF-1/CXCR4 antagonism and chemotherapy in relapsed acute myeloid leukemia
- (2008) F A Fierro et al. LEUKEMIA
- The CXCR4 antagonist AMD3100 impairs survival of human AML cells and induces their differentiation
- (2008) S Tavor et al. LEUKEMIA
- CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers
- (2008) J A Burger et al. LEUKEMIA
- Prognostic value of CXCR4 and FAK expression in acute myelogenous leukemia
- (2008) Emmanuelle Tavernier-Tardy et al. LEUKEMIA RESEARCH
- CXCR4 up-regulation by imatinib induces chronic myelogenous leukemia (CML) cell migration to bone marrow stroma and promotes survival of quiescent CML cells
- (2008) L. Jin et al. MOLECULAR CANCER THERAPEUTICS
- Haematopoietic stem cell release is regulated by circadian oscillations
- (2008) Simón Méndez-Ferrer et al. NATURE
- Leukemic Cells Create Bone Marrow Niches That Disrupt the Behavior of Normal Hematopoietic Progenitor Cells
- (2008) Angela Colmone et al. SCIENCE
- Targeting FLT3 for the Treatment of Leukemia
- (2008) Donald Small SEMINARS IN HEMATOLOGY
- Valproic Acid Increases CXCR4 Expression in Hematopoietic Stem/Progenitor Cells by Chromatin Remodeling
- (2008) Hilal Gul et al. STEM CELLS AND DEVELOPMENT
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started