1-(3-Biaryloxy-2-oxopropyl)indole-5-carboxylic Acids and Related Compounds as Dual Inhibitors of Human Cytosolic Phospholipase A2α and Fatty Acid Amide Hydrolase

Recent advances in the discovery and evaluation of fatty acid amide hydrolase inhibitors

(2010) Hongfeng Deng   Expert Opinion on Drug Discovery

1-(5-Carboxyindol-1-yl)propan-2-one Inhibitors of Human Cytosolic Phospholipase A2α with Reduced Lipophilicity: Synthesis, Biological Activity, Metabolic Stability, Solubility, Bioavailability, And Topical in Vivo Activity

(2010) Andreas Drews et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeting Fatty Acid Amide Hydrolase (FAAH) to Treat Pain and Inflammation

(2009) Joel E. Schlosburg et al.   AAPS Journal

High-performance liquid chromatographic assay with fluorescence detection for the evaluation of inhibitors against fatty acid amide hydrolase

(2009) Laura Forster et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

High-performance liquid chromatography assay with fluorescence detection for the evaluation of inhibitors against human recombinant monoacylglycerol lipase

(2009) Angela Holtfrerich et al.   ANALYTICAL BIOCHEMISTRY

1-Indol-1-yl-propan-2-ones and related heterocyclic compounds as dual inhibitors of cytosolic phospholipase A2α and fatty acid amide hydrolase

(2009) Laura Forster et al.   BIOORGANIC & MEDICINAL CHEMISTRY

1-(5-Carboxyindol-1-yl)propan-2-ones as inhibitors of human cytosolic phospholipase A2α: Synthesis and properties of bioisosteric benzimidazole, benzotriazole and indazole analogues

(2009) Stefanie Bovens et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Fatty acid amide hydrolase as a potential therapeutic target for the treatment of pain and CNS disorders

(2009) Kay Ahn et al.   Expert Opinion on Drug Discovery

Phospholipase A2inhibitors as potential therapeutic agents for the treatment of inflammatory diseases

(2009) Victoria Magrioti et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Enzymatic Pathways That Regulate Endocannabinoid Signaling in the Nervous System

(2008) Kay Ahn et al.   CHEMICAL REVIEWS

Overview of the Chemical Families of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase Inhibitors

(2008) Severine Vandevoorde   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Indole Cytosolic Phospholipase A2α Inhibitors: Discovery and in Vitro and in Vivo Characterization of 4-{3-[5-Chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic Acid, Efipladib

(2008) John C. McKew et al.   JOURNAL OF MEDICINAL CHEMISTRY