Synthesis of Pyrrolophenanthridine Alkaloids Based on C(sp3)H and C(sp2)H Functionalization Reactions

Palladium(0)-Catalyzed CarbonHydrogen Bond Functionalization for the Synthesis of Indoloquinazolinones

(2014) Chihiro Tsukano et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of Spirooxindoles from Carbamoyl Chlorides via Cyclopropyl Methine C(sp3)–H Activation Using Palladium Catalyst

(2013) Chihiro Tsukano et al.   CHEMISTRY LETTERS

Expeditious Approach to Pyrrolophenanthridones, Phenanthridines, and Benzo[c]phenanthridines via Organocatalytic Direct Biaryl-Coupling Promoted by Potassium tert-Butoxide

(2013) Subhadip De et al.   JOURNAL OF ORGANIC CHEMISTRY

Silver-Promoted, Palladium-Catalyzed Direct Arylation of Cyclopropanes: Facile Access to Spiro 3,3′-Cyclopropyl Oxindoles

(2013) Carolyn L. Ladd et al.   ORGANIC LETTERS

Total Syntheses of Complanadines A and B

(2012) Le Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Amidation by Chemoselective C(sp3)H Activation: Concise Route to Oxindoles Using a Carbamoyl Chloride Precursor

(2012) Chihiro Tsukano et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(0)-Catalyzed Enantioselective CH Arylation of Cyclopropanes: Efficient Access to Functionalized Tetrahydroquinolines

(2012) Tanguy Saget et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Monodentate Phosphines and Bulky Carboxylic Acids: Cooperative Effects in Palladium-Catalyzed Enantioselective C(sp3)-H Functionalization

(2012) Tanguy Saget et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals

(2012) Junichiro Yamaguchi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Activation of a C(sp3)H Bond by a Transient σ-Alkylpalladium(II) Complex: Synthesis of Spirooxindoles Through a Palladium-Catalyzed Domino Carbopalladation/C(sp3)C(sp3) Bond-Forming Process

(2012) Tiffany Piou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CH Activation: A Complementary Tool in the Total Synthesis of Complex Natural Products

(2012) David Y.-K. Chen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Construction of heterocyclic scaffolds via transition metal-catalyzed sp3 C–H functionalization

(2012) Ming Zhang et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Palladium-Catalyzed Cascade Process Consisting of Isocyanide Insertion and Benzylic C(sp3)–H Activation: Concise Synthesis of Indole Derivatives

(2012) Takeshi Nanjo et al.   ORGANIC LETTERS

Intramolecular Direct Dehydrohalide Coupling Promoted by KOtBu: Total Synthesis of Amaryllidaceae Alkaloids Anhydrolycorinone and Oxoassoanine

(2012) Subhadip De et al.   ORGANIC LETTERS

Synthesis and anti-leukaemic activity of pyrrolo[3,2,1-hi]indole-1,2-diones, pyrrolo[3,2,1-ij]quinoline-1,2-diones and other polycyclic isatin derivatives

(2012) Lidia Matesic et al.   TETRAHEDRON

Synthesis of pyrrolophenanthridone alkaloid kalbretorine from indolecarboxylic acids via hypervalent iodine(III) mediated halodecarboxylation and reduction

(2012) Yasuyoshi Miki et al.   TETRAHEDRON LETTERS

Fused Indolines by Palladium-Catalyzed Asymmetric CC Coupling Involving an Unactivated Methylene Group

(2011) Masafumi Nakanishi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic Palladium-Catalyzed C(sp3)H Activation/C(sp3)O Bond Formation: A Direct, Step-Economical Route to Benzolactones

(2011) Petr Novák et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In search of a cytostatic agent derived from the alkaloid lycorine: Synthesis and growth inhibitory properties of lycorine derivatives

(2011) Nikolai M. Evdokimov et al.   BIOORGANIC & MEDICINAL CHEMISTRY

C–H functionalization logic in total synthesis

(2011) Will R. Gutekunst et al.   CHEMICAL SOCIETY REVIEWS

Recent developments in natural product synthesis using metal-catalysed C–H bond functionalisation

(2011) Lindsay McMurray et al.   CHEMICAL SOCIETY REVIEWS

Isolation of narciprimine from Cyrtanthus contractus (Amaryllidaceae) and evaluation of its acetylcholinesterase inhibitory activity

(2011) Jerald J. Nair et al.   JOURNAL OF ETHNOPHARMACOLOGY

Aerobic Pd-Catalyzed sp3C−H Olefination: A Route to Both N-Heterocyclic Scaffolds and Alkenes

(2011) Kara J. Stowers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Tricyclic Nitrogen Heterocycles by a Sequence of Palladium-Catalyzed N–H and C(sp3)–H Arylations

(2011) Mathieu Guyonnet et al.   ORGANIC LETTERS

Challenge and progress: palladium-catalyzed sp3 C–H activation

(2011) Hu Li et al.   Catalysis Science & Technology

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

Functionalization of Organic Molecules by Transition-Metal-Catalyzed C(sp3)H Activation

(2010) Rodolphe Jazzar et al.   CHEMISTRY-A EUROPEAN JOURNAL

Intramolecular Palladium-Catalyzed Alkane C−H Arylation from Aryl Chlorides

(2010) Sophie Rousseaux et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Investigation of the Mechanism of C(sp3)−H Bond Cleavage in Pd(0)-Catalyzed Intramolecular Alkane Arylation Adjacent to Amides and Sulfonamides

(2010) Sophie Rousseaux et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iridium-Catalyzed, Silyl-Directed Borylation of Nitrogen-Containing Heterocycles

(2010) Daniel W. Robbins et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Expeditious Synthesis of Phenanthridines from Benzylamines via Dual Palladium Catalysis

(2010) Giovanni Maestri et al.   ORGANIC LETTERS

Palladium-Catalyzed Amidation of Unactivated C(sp3)H Bonds: from Anilines to Indolines

(2009) Julia J. Neumann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)-Catalyzed CH Activation/CC Cross-Coupling Reactions: Versatility and Practicality

(2009) Xiao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Constituents ofCrinum asiaticumL. var.sinicumBaker and Their Cytotoxic Activities

(2009) Qian Sun et al.   CHEMISTRY & BIODIVERSITY

Lycorine, the Main Phenanthridine Amaryllidaceae Alkaloid, Exhibits Significant Antitumor Activity in Cancer Cells That Display Resistance to Proapoptotic Stimuli: An Investigation of Structure−Activity Relationship and Mechanistic Insight

(2009) Delphine Lamoral-Theys et al.   JOURNAL OF MEDICINAL CHEMISTRY

Anticancer evaluation of structurally diverse Amaryllidaceae alkaloids and their synthetic derivatives

(2009) Antonio Evidente et al.   PHYTOCHEMISTRY REVIEWS

Catalytic Sequential Reactions Involving Palladacycle-Directed Aryl Coupling Steps

(2008) Marta Catellani et al.   ACCOUNTS OF CHEMICAL RESEARCH

Natural Products and their Derivatives as Cholinesterase Inhibitors in the Treatment of Neurodegenerative Disorders: An Update

(2008) Monica Loizzo et al.   CURRENT MEDICINAL CHEMISTRY

Palladium-Catalyzed sp3CH Activation of Simple Alkyl Groups: Direct Preparation of Indoline Derivatives fromN-Alkyl-2-bromoanilines

(2008) Toshiaki Watanabe et al.   ORGANIC LETTERS