Alkylation of Pyridines at Their 4-Positions with Styrenes plus Yttrium Reagent or Benzyl Grignard Reagents

Transition-Metal-Free BF3-Mediated Oxidative and Non-Oxidative Cross-Coupling of Pyridines

(2014) Quan Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

BF3-Mediated Oxidative Cross-Coupling of Pyridines with Alkynyllithium Reagents and Further Reductive Functionalizations of the Pyridine Scaffold

(2014) Paul Knochel et al.   SYNTHESIS-STUTTGART

Optimizing the Physicochemical Properties of Raf/MEK Inhibitors by Nitrogen Scanning

(2014) Toshihiro Aoki et al.   ACS Medicinal Chemistry Letters

Cobalt-Catalyzed C4-Selective Direct Alkylation of Pyridines

(2013) Takashi Andou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

RECENT PROGRESS IN METAL ASSISTED MULTICOMPONENT SYNTHESES OF HETEROCYCLES

(2013) Pradip Kumar Maji et al.   HETEROCYCLES

Cushing’s Syndrome: Development of Highly Potent and Selective CYP11B1 Inhibitors of the (Pyridylmethyl)pyridine Type

(2013) Juliette Emmerich et al.   JOURNAL OF MEDICINAL CHEMISTRY

Transition-Metal-Free BF3-Mediated Regioselective Direct Alkylation and Arylation of Functionalized Pyridines Using Grignard or Organozinc Reagents

(2013) Quan Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Diarylmethyl C(sp3)–C(sp2) Bond Formation: A New Coupling Approach toward Triarylmethanes

(2013) Ying Xia et al.   ORGANIC LETTERS

Chiral 1,1-diaryl compounds as important pharmacophores

(2013) Dana Ameen et al.   MedChemComm

Palladium-Catalyzed C-2 Selective CH Olefination of Pyridines

(2012) Ping Wen et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Arylation of a CH Bond in Pyridine and Related Six-Membered N-Heteroarenes Using Organozinc Reagents

(2012) Isao Hyodo et al.   Chemistry-An Asian Journal

Analogues of Fenarimol Are Potent Inhibitors of Trypanosoma cruzi and Are Efficacious in a Murine Model of Chagas Disease

(2012) Martine Keenan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Nickel-Catalyzed Cross Couplings of Benzylic Ammonium Salts and Boronic Acids: Stereospecific Formation of Diarylethanes via C–N Bond Activation

(2012) Prantik Maity et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed C(sp3)–H Arylation of Diarylmethanes at Room Temperature: Synthesis of Triarylmethanes via Deprotonative-Cross-Coupling Processes

(2012) Jiadi Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chichibabin-Type Direct Alkylation of Pyridyl Alcohols with Alkyl Lithium Reagents

(2012) Jenna L. Jeffrey et al.   ORGANIC LETTERS

Recent Developments in Palladium-Catalyzed Formation of Five- and Six-Membered Fused Heterocycles

(2012) K. Majumdar et al.   SYNTHESIS-STUTTGART

Facile synthesis of diarylmethanes via quinone methides

(2012) Kassrin Tangdenpaisal et al.   TETRAHEDRON

Regio- and Chemoselective Metalation of Arenes and Heteroarenes Using Hindered Metal Amide Bases

(2011) Benjamin Haag et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope

(2011) Lutz Ackermann   CHEMICAL REVIEWS

Rare-Earth-Catalyzed C–H Bond Addition of Pyridines to Olefins

(2011) Bing-Tao Guan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New Preparation of Benzylic Aluminum and Zinc Organometallics by Direct Insertion of Aluminum Powder

(2011) Tobias D. Blümke et al.   ORGANIC LETTERS

Transition-Metal-Catalyzed C-H Functionalization for the Synthesis of Substituted Pyridines

(2011) Yoshiaki Nakao   SYNTHESIS-STUTTGART

Minisci reactions: Versatile CH-functionalizations for medicinal chemists

(2011) Matthew A. J. Duncton   MedChemComm

Discovery of a Potent HIV Integrase Inhibitor That Leads to a Prodrug with Significant anti-HIV Activity

(2011) Byung I. Seo et al.   ACS Medicinal Chemistry Letters

Acceleration of the Substitution of Silanes with Grignard Reagents by Using either LiCl or YCl3/MeLi

(2010) Naoki Hirone et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

Recent Strategies for the Synthesis of Pyridine Derivatives

(2010) Matthew D. Hill   CHEMISTRY-A EUROPEAN JOURNAL

Selective C-4 Alkylation of Pyridine by Nickel/Lewis Acid Catalysis

(2010) Yoshiaki Nakao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bimetallic Nickel Aluminun MediatedPara-Selective Alkenylation of Pyridine: Direct Observation of η2,η1-Pyridine Ni(0)−Al(III) Intermediates Prior to C−H Bond Activation

(2010) Chung-Chih Tsai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transition-Metal-Catalyzed Direct Arylation of (Hetero)Arenes by CH Bond Cleavage

(2009) Lutz Ackermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)-Catalyzed CH Activation/CC Cross-Coupling Reactions: Versatility and Practicality

(2009) Xiao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Di-substituted pyridinyl aminohydantoins as potent and highly selective human β-secretase (BACE1) inhibitors

(2009) Michael S. Malamas et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Combinations of Alkyllithiums and Lithium Aminoalkoxides for Generation of Functional Pyridine Organometallics and Derivatives

(2009) Philippe C. Gros et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A Strategy for C−H Activation of Pyridines:  Direct C-2 Selective Alkenylation of Pyridines by Nickel/Lewis Acid Catalysis

(2008) Yoshiaki Nakao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Yttrium-Mediated Conversion of Vinyl Grignard Reagent to a 1,2-Dimetalated Ethane and Its Synthetic Application

(2008) Ryoichi Tanaka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY