Shape-Persistent and Adaptive Multivalency: Rigid Transgeden (TGD) and Flexible PAMAM Dendrimers for Heparin Binding

Nanoscale self-assembled multivalent (SAMul) heparin binders in highly competitive, biologically relevant, aqueous media

(2014) Stephen M. Bromfield et al.   Chemical Science

Cationic Dendron-Bearing Lipids: Investigating Structure–Activity Relationships for Small Interfering RNA Delivery

(2013) Yu Zhang et al.   BIOMACROMOLECULES

Efficient gene transfection in the neurotypic cells by star-shaped polymer consisting of β-cyclodextrin core and poly(amidoamine) dendron arms

(2013) Bing Liang et al.   CARBOHYDRATE POLYMERS

A simple new competition assay for heparin binding in serum applied to multivalent PAMAM dendrimers

(2013) Stephen M. Bromfield et al.   CHEMICAL COMMUNICATIONS

Heparin sensing and binding – taking supramolecular chemistry towards clinical applications

(2013) Stephen M. Bromfield et al.   CHEMICAL SOCIETY REVIEWS

Mallard Blue: A High-Affinity Selective Heparin Sensor That Operates in Highly Competitive Media

(2013) Stephen M. Bromfield et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PPV–PAMAM Hybrid Dendrimers: Self-Assembly and Stabilization of Gold Nanoparticles

(2013) Javier Guerra et al.   MACROMOLECULES

Impact of siRNA Overhangs for Dendrimer-Mediated siRNA Delivery and Gene Silencing

(2013) Paola Posocco et al.   MOLECULAR PHARMACEUTICS

Self-assembled multivalent RGD-peptide arrays – morphological control and integrin binding

(2013) Daniel J. Welsh et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Double-degradable responsive self-assembled multivalent arrays – temporary nanoscale recognition between dendrons and DNA

(2013) Anna Barnard et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Knocking Down HMGB1 Using Dendrimer-Delivered siRNA Unveils Its Key Role in NMDA-Induced Autophagy in Rat Cortical Neurons

(2013) María D. Pérez-Carrión et al.   PHARMACEUTICAL RESEARCH

Intermolecular forces between low generation PAMAM dendrimer condensed DNA helices: role of cation architecture

(2013) Min An et al.   Soft Matter

An Amphiphilic Dendrimer for Effective Delivery of Small Interfering RNA and Gene Silencing In Vitro and In Vivo

(2012) Tianzhu Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Self-Assembled Multivalency: Dynamic Ligand Arrays for High-Affinity Binding

(2012) Anna Barnard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multivalency as a Chemical Organization and Action Principle

(2012) Carlo Fasting et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Polyamidoamine Dendron-Bearing Lipids as a Nonviral Vector: Influence of Dendron Generation

(2012) Kenji Kono et al.   BIOCONJUGATE CHEMISTRY

Lipid modified triblock PAMAM-based nanocarriers for siRNA drug co-delivery

(2012) Swati Biswas et al.   BIOMATERIALS

Role of Generation, Architecture, pH and Ionic Strength on Successful siRNA Delivery and Transfection by Hybrid PPV-PAMAM Dendrimers

(2012) G. M. Pavan et al.   CURRENT MEDICINAL CHEMISTRY

Tell Me Something I Do Not Know. Multiscale Molecular Modeling of Dendrimer/ Dendron Organization and Self-Assembly In Gene Therapy

(2012) P. Posocco et al.   CURRENT MEDICINAL CHEMISTRY

Polyamidoamine dendron-bearing lipid assemblies: Their morphologies and gene transfection ability

(2012) Shinki Iwashita et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

Characterization of magnetic nanoparticles modified with thiol functionalized PAMAM dendron for DNA recovery

(2012) Tsuyoshi Tanaka et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Molecular Dynamics Simulations for Complexation of DNA with 2 kDa PEI Reveal Profound Effect of PEI Architecture on Complexation

(2012) Chongbo Sun et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Efficient in Vitro siRNA Delivery and Intramuscular Gene Silencing Using PEG-Modified PAMAM Dendrimers

(2012) Yin Tang et al.   MOLECULAR PHARMACEUTICS

Self-Assembling Ligands for Multivalent Nanoscale Heparin Binding

(2011) Ana C. Rodrigo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structurally Flexible Triethanolamine Core PAMAM Dendrimers Are Effective Nanovectors for DNA Transfection in Vitro and in Vivo to the Mouse Thymus

(2011) Xiaoxuan Liu et al.   BIOCONJUGATE CHEMISTRY

Molecular Dynamics Simulations of PEI Mediated DNA Aggregation

(2011) Chongbo Sun et al.   BIOMACROMOLECULES

Efficient, Non-Toxic Hybrid PPV-PAMAM Dendrimer as a Gene Carrier for Neuronal Cells

(2011) Ana C. Rodrigo et al.   BIOMACROMOLECULES

Dendronized Chitosan Derivative as a Biocompatible Gene Delivery Carrier

(2011) Junjie Deng et al.   BIOMACROMOLECULES

Epidermal Growth Factor–PEG Functionalized PAMAM-Pentaethylenehexamine Dendron for Targeted Gene Delivery Produced by Click Chemistry

(2011) Haijun Yu et al.   BIOMACROMOLECULES

The effect of pH on PAMAM dendrimer–siRNA complexation — Endosomal considerations as determined by molecular dynamics simulation

(2011) Defang Ouyang et al.   BIOPHYSICAL CHEMISTRY

Elucidating the molecular mechanism of PAMAM–siRNA dendriplex self-assembly: Effect of dendrimer charge density

(2011) Linda B. Jensen et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Star-shaped polymers consisting of a β-cyclodextrin core and poly(amidoamine) dendron arms: binding and release studies with methotrexate and siRNA

(2011) Junjie Deng et al.   JOURNAL OF MATERIALS CHEMISTRY

Cationic Derivatives of Dextran and Hydroxypropylcellulose as Novel Potential Heparin Antagonists

(2011) Kamil Kamiński et al.   JOURNAL OF MEDICINAL CHEMISTRY

Degradable Self-Assembling Dendrons for Gene Delivery: Experimental and Theoretical Insights into the Barriers to Cellular Uptake

(2011) Anna Barnard et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Unimolecular Micelles of Amphiphilic Dendrimer-like Star Polymer with Various Functional Surface Groups

(2011) Weiqiang Cao et al.   MACROMOLECULES

Hydrophobically Modified Dendrons: Developing Structure−Activity Relationships for DNA Binding and Gene Transfection

(2011) Simon P. Jones et al.   MOLECULAR PHARMACEUTICS

Interaction of heparin with cationic molecular probes: Probe charge is a major determinant of binding stoichiometry and affinity

(2010) Helga Szelke et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A fluorescent probe for the quantification of heparin in clinical samples with minimal matrix interference

(2010) Helga Szelke et al.   CHEMICAL COMMUNICATIONS

Quantifying the Effect of Surface Ligands on Dendron-DNA Interactions: Insights into Multivalency through a Combined Experimental and Theoretical Approach

(2010) Simon P. Jones et al.   CHEMISTRY-A EUROPEAN JOURNAL

PAMAM Dendrimers for siRNA Delivery: Computational and Experimental Insights

(2010) Giovanni Maria Pavan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Host−Guest Chemistry of Dendrimer−Drug Complexes. 5. Insights into the Design of Formulations for Noninvasive Delivery of Heparin Revealed by Isothermal Titration Calorimetry and NMR Studies

(2010) Xueyan Feng et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Ability to Adapt: Different Generations of PAMAM Dendrimers Show Different Behaviors in Binding siRNA

(2010) Giovanni M. Pavan et al.   JOURNAL OF PHYSICAL CHEMISTRY B

The influence of dendron's architecture on the “rigid” and “flexible” behaviour in binding DNA—a modelling study

(2010) Giovanni M. Pavan et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Less is more – multiscale modelling of self-assembling multivalency and its impact on DNA binding and gene delivery

(2010) Paola Posocco et al.   Chemical Science

PAMAM Dendrimers Mediate siRNA Delivery to Target Hsp27 and Produce Potent Antiproliferative Effects on Prostate Cancer Cells

(2009) Xiao-xuan Liu et al.   ChemMedChem

Modeling the Multivalent Recognition between Dendritic Molecules and DNA: Understanding How Ligand “Sacrifice” and Screening Can Enhance Binding

(2009) Giovanni M. Pavan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PAMAM Dendrimers Undergo pH Responsive Conformational Changes without Swelling

(2009) Yi Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Interactions between dendrimers and heparin and their implications for the anti-prion activity of dendrimers

(2009) Barbara Klajnert et al.   NEW JOURNAL OF CHEMISTRY

Highly Selective and Sensitive Heparin Probing from Supramolecular Assembly of Pyrene Derivatives

(2009) Lintao Zeng et al.   ORGANIC LETTERS

The convenient fluorescence turn-on detection of heparin with a silole derivative featuring an ammonium group

(2008) Ming Wang et al.   CHEMICAL COMMUNICATIONS

Optical sensing of sulfate by polymethinium salt receptors: colorimetric sensor for heparin

(2008) Tomáš Bříza et al.   CHEMICAL COMMUNICATIONS

Nonviral Vectors for Gene Delivery

(2008) Meredith A. Mintzer et al.   CHEMICAL REVIEWS

A Multicolor Cationic Conjugated Polymer for Naked-Eye Detection and Quantification of Heparin

(2008) Kan-Yi Pu et al.   MACROMOLECULES

Surfen, a small molecule antagonist of heparan sulfate

(2008) M. Schuksz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of heparin chemosensors through diversity oriented fluorescence library approach

(2007) Shenliang Wang et al.   CHEMICAL COMMUNICATIONS