Nanoscale self-assembled multivalent (SAMul) heparin binders in highly competitive, biologically relevant, aqueous media

A simple new competition assay for heparin binding in serum applied to multivalent PAMAM dendrimers

(2013) Stephen M. Bromfield et al.   CHEMICAL COMMUNICATIONS

Multi-stimuli responsive macromolecules and their assemblies

(2013) Jiaming Zhuang et al.   CHEMICAL SOCIETY REVIEWS

Heparin sensing and binding – taking supramolecular chemistry towards clinical applications

(2013) Stephen M. Bromfield et al.   CHEMICAL SOCIETY REVIEWS

Mallard Blue: A High-Affinity Selective Heparin Sensor That Operates in Highly Competitive Media

(2013) Stephen M. Bromfield et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-assembled multivalent RGD-peptide arrays – morphological control and integrin binding

(2013) Daniel J. Welsh et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Crafting precise multivalent architectures

(2013) Paul M. Levine et al.   MedChemComm

Self-Assembled Multivalency: Dynamic Ligand Arrays for High-Affinity Binding

(2012) Anna Barnard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multivalency as a Chemical Organization and Action Principle

(2012) Carlo Fasting et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Analysis of Immediate Stress Mechanisms upon Injection of Polymeric Micelles and Related Colloidal Drug Carriers: Implications on Drug Targeting

(2012) Tobias Miller et al.   BIOMACROMOLECULES

Cationic derivative of dextran reverses anticoagulant activity of unfractionated heparin in animal models of arterial and venous thrombosis

(2012) Bartlomiej Kalaska et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Supramolecular chemical biology; bioactive synthetic self-assemblies

(2012) Katja Petkau-Milroy et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Self-Assembling Ligands for Multivalent Nanoscale Heparin Binding

(2011) Ana C. Rodrigo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cationic Derivatives of Dextran and Hydroxypropylcellulose as Novel Potential Heparin Antagonists

(2011) Kamil Kamiński et al.   JOURNAL OF MEDICINAL CHEMISTRY

Degradable Self-Assembling Dendrons for Gene Delivery: Experimental and Theoretical Insights into the Barriers to Cellular Uptake

(2011) Anna Barnard et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stability of Self-Assembled Polymeric Micelles in Serum

(2011) Jiao Lu et al.   MACROMOLECULES

Hydrophobically Modified Dendrons: Developing Structure−Activity Relationships for DNA Binding and Gene Transfection

(2011) Simon P. Jones et al.   MOLECULAR PHARMACEUTICS

Nanomedicine(s) under the Microscope

(2011) Ruth Duncan et al.   MOLECULAR PHARMACEUTICS

Comparing dendritic and self-assembly strategies to multivalency—RGD peptide–integrin interactions

(2011) Daniel J. Welsh et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Combining supramolecular chemistry with biology

(2010) Dana A. Uhlenheuer et al.   CHEMICAL SOCIETY REVIEWS

In Vivo Neutralization of Unfractionated Heparin and Low-Molecular-Weight Heparin by a Novel Salicylamide Derivative

(2010) Jacqueline Kuziej et al.   CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS

Allergic shock and death associated with protamine administration in a diabetic patient

(2010) Yan-Qi Chu et al.   CLINICAL THERAPEUTICS

Host−Guest Chemistry of Dendrimer−Drug Complexes. 5. Insights into the Design of Formulations for Noninvasive Delivery of Heparin Revealed by Isothermal Titration Calorimetry and NMR Studies

(2010) Xueyan Feng et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Analysis of the Complex Formation of Heparin with Protamine by Light Scattering and Analytical Ultracentrifugation: Implications for Blood Coagulation Management

(2010) Jürgen Maurer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanomedicine

(2010) Betty Y.S. Kim et al.   NEW ENGLAND JOURNAL OF MEDICINE

Less is more – multiscale modelling of self-assembling multivalency and its impact on DNA binding and gene delivery

(2010) Paola Posocco et al.   Chemical Science

“On-Off” Multivalent Recognition: Degradable Dendrons for Temporary High-Affinity DNA Binding

(2009) Daniel J. Welsh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Supramolecular Polymer as a Self-Assembling Polyvalent Scaffold

(2009) Marion K. Müller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Overcoming the barriers in micellar drug delivery: loading efficiency,in vivostability, and micelle–cell interaction

(2009) Sungwon Kim et al.   Expert Opinion on Drug Delivery

Polycationic calix[8]arene receptors grafted onto polymeric matrix: smart material for heparin neutralization

(2009) Tommaso Mecca et al.   POLYMERS FOR ADVANCED TECHNOLOGIES

Serious Anaphylactic Reactions due to Protamine Sulfate: A Systematic Literature Review

(2008) Mads Nybo et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Synergistic effects in gene delivery—a structure–activity approach to the optimisation of hybrid dendritic–lipidic transfection agents

(2008) Simon P. Jones et al.   CHEMICAL COMMUNICATIONS

Synthesis and Evaluation of Pegylated Dendrimeric Nanocarrier for Pulmonary Delivery of Low Molecular Weight Heparin

(2008) Shuhua Bai et al.   PHARMACEUTICAL RESEARCH

Surfen, a small molecule antagonist of heparan sulfate

(2008) M. Schuksz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heparin: From animal organ extract to designer drug

(2007) S. Middeldorp   THROMBOSIS RESEARCH