Targeting Matrix Metalloproteinases: Design of a Bifunctional Inhibitor for Presentation by Tumour-Associated Galectins

The roles of Galectin-3 in autoimmunity and tumor progression

(2012) Gordana Radosavljevic et al.   IMMUNOLOGIC RESEARCH

Toward Comprehensive Analysis of the Galectin Network in Chicken: Unique Diversity of Galectin-3 and Comparison of its Localization Profile in Organs of Adult Animals to the Other Four Members of this Lectin Family

(2011) Herbert Kaltner et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Inhibitory potential of chemical substitutions at bioinspired sites of β-d-galactopyranose on neoglycoprotein/cell surface binding of two classes of medically relevant lectins

(2011) Denis Giguère et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Combining carbohydrate substitutions at bioinspired positions with multivalent presentation towards optimising lectin inhibitors: case study with calixarenes

(2011) Sabine André et al.   CHEMICAL COMMUNICATIONS

Quantitative immunohistochemical fingerprinting of adhesion/growth-regulatory galectins in salivary gland tumours: divergent profiles with diagnostic potential

(2011) Myriam Remmelink et al.   HISTOPATHOLOGY

The role of galectins in colorectal cancer progression

(2011) Hannah Barrow et al.   INTERNATIONAL JOURNAL OF CANCER

Symmetric dithiodigalactoside: strategic combination of binding studies and detection of selectivity between a plant toxin and human lectins

(2011) Sonsoles Martín-Santamaría et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

From lectin structure to functional glycomics: principles of the sugar code

(2011) Hans-Joachim Gabius et al.   TRENDS IN BIOCHEMICAL SCIENCES

Human galectin-3 (Mac-2 antigen): Defining molecular switches of affinity to natural glycoproteins, structural and dynamic aspects of glycan binding by flexible ligand docking and putative regulatory sequences in the proximal promoter region

(2010) Mickaël Krzeminski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Structure-based approach to nanomolar, water soluble matrix metalloproteinases inhibitors (MMPIs)

(2010) Emanuele Attolino et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Tumor suppressor p16INK4a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model

(2010) Hugo Sanchez-Ruderisch et al.   FEBS Journal

Matrilysin-1 (MMP7) cleaves galectin-3 and inhibits wound healing in intestinal epithelial cells

(2010) Manjula Puthenedam et al.   INFLAMMATORY BOWEL DISEASES

N-domain of human adhesion/growth-regulatory galectin-9: Preference for distinct conformers and non-sialylated N-glycans and detection of ligand-induced structural changes in crystal and solution

(2010) Dolores Solís et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cleavage of galectin-3 by matrix metalloproteases induces angiogenesis in breast cancer

(2010) Pratima Nangia-Makker et al.   INTERNATIONAL JOURNAL OF CANCER

Synthesis and screening of a small glycomimetic library for inhibitory activity on medically relevant galactoside-specific lectins in assays of increasing biorelevance

(2010) Sabine André et al.   NEW JOURNAL OF CHEMISTRY

Binding studies of adhesion/growth-regulatory galectins with glycoconjugates monitored by surface plasmon resonance and NMR spectroscopy

(2010) F. Javier Muñoz et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Biotin-Tagged Probes for MMP Expression and Activation: Design, Synthesis, and Binding Properties

(2009) Elisa Dragoni et al.   BIOCONJUGATE CHEMISTRY

Calix[n]arene‐Based Glycoclusters: Bioactivity of Thiourea‐Linked Galactose/Lactose Moieties as Inhibitors of Binding of Medically Relevant Lectins to a Glycoprotein and Cell‐Surface Glycoconjugates and Selectivity among Human Adhesion/Growth‐Regulatory Galectins

(2008) Sabine André et al.   CHEMBIOCHEM

Galectin-1 Is a Novel Functional Receptor for Tissue Plasminogen Activator in Pancreatic Cancer

(2008) Oriol Roda et al.   GASTROENTEROLOGY

Increased expression and altered intracellular distribution of adhesion/growth-regulatory lectins galectins-1 and -7 during tumour progression in hypopharyngeal and laryngeal squamous cell carcinomas

(2008) S Saussez et al.   HISTOPATHOLOGY

Pharmacoproteomics of a Metalloproteinase Hydroxamate Inhibitor in Breast Cancer Cells: Dynamics of Membrane Type 1 Matrix Metalloproteinase-Mediated Membrane Protein Shedding

(2008) G. S. Butler et al.   MOLECULAR AND CELLULAR BIOLOGY

Galectin-3: A useful biomarker for differential diagnosis of brain tumors

(2008) Sung-Hye Park et al.   NEUROPATHOLOGY

Matrix metalloproteinases at cancer tumor–host interface

(2007) A NOEL et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

MMPs as therapeutic targets—Still a viable option?

(2007) B FINGLETON   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY