Applications of Bartoli indole synthesis

Furanylazaindoles: Potent Anticancer Agents in Vitro and in Vivo

(2013) Hsueh-Yun Lee et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inhibitors of Human Immunodeficiency Virus Type 1 (HIV-1) Attachment. 12. Structure–Activity Relationships Associated with 4-Fluoro-6-azaindole Derivatives Leading to the Identification of 1-(4-Benzoylpiperazin-1-yl)-2-(4-fluoro-7-[1,2,3]triazol-1-yl-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-585248)

(2013) Alicia Regueiro-Ren et al.   JOURNAL OF MEDICINAL CHEMISTRY

Convergent Total Syntheses of the Amaryllidaceae Alkaloids Lycoranine A, Lycoranine B, and 2-Methoxypratosine

(2013) Hye Sun Kim et al.   JOURNAL OF ORGANIC CHEMISTRY

Electrochemiluminescence biosensor for Ramos cells based on a nanostructured conducting polymer composite material (PICA-MWNTs)

(2013) Guangming Nie et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Transition-Metal-Free Direct Arylation: Synthesis of Halogenated 2-Amino-2′-hydroxy-1,1′-biaryls and Mechanism by DFT Calculations

(2013) Hongyin Gao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

5,10-Dihydroindolo[3,2-b]indole-Based Copolymers with Alternating Donor and Acceptor Moieties for Organic Photovoltaics

(2013) Zbyslaw R. Owczarczyk et al.   MACROMOLECULES

Biomedical Importance of Indoles

(2013) Nagendra Kaushik et al.   MOLECULES

Simple indole alkaloids and those with a non-rearranged monoterpenoid unit

(2013) Minoru Ishikura et al.   NATURAL PRODUCT REPORTS

One-Pot Construction of 3,3′-Bisindolylmethanes through Bartoli Indole Synthesis

(2013) Takumi Abe et al.   ORGANIC LETTERS

Recent advances in the synthesis and properties of 4-, 5-, 6- or 7-azaindoles

(2013) Jean-Yves Mérour et al.   TETRAHEDRON

Synthesis of diverse indole libraries on polystyrene resin – Scope and limitations of an organometallic reaction on solid supports

(2012) Kerstin Knepper et al.   Beilstein Journal of Organic Chemistry

Discovery of 1H-pyrrolo[2,3-c]pyridine-7-carboxamides as novel, allosteric mGluR5 antagonists

(2012) Manuel Koller et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Inhibitors of HIV-1 attachment. Part 10. The discovery and structure–activity relationships of 4-azaindole cores

(2012) Tao Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids

(2012) Arndt W. Schmidt et al.   CHEMICAL REVIEWS

Indoles in Multicomponent Processes (MCPs)

(2012) Morteza Shiri   CHEMICAL REVIEWS

Progress in palladium-based catalytic systems for the sustainable synthesis of annulated heterocycles: a focus on indole backbones

(2012) Mélanie Platon et al.   CHEMICAL SOCIETY REVIEWS

New strategies for the synthesis of N-alkylated indoles (Review)

(2012) A. V. Karchava et al.   Chemistry of Heterocyclic Compounds

Total Synthesis of (+)-trans-Trikentrin A

(2012) Iris R. M. Tébéka et al.   CHEMISTRY-A EUROPEAN JOURNAL

Indole molecules as inhibitors of tubulin polymerization: potential new anticancer agents

(2012) Shivaputra A Patil et al.   Future Medicinal Chemistry

A Brief Review of Carbazole-Based Photorefractive Liquid Crystalline Materials

(2012) M. Manickam et al.   ISRAEL JOURNAL OF CHEMISTRY

Novel 3-Azaindolyl-4-arylmaleimides Exhibiting Potent Antiangiogenic Efficacy, Protein Kinase Inhibition, and Antiproliferative Activity

(2012) Christopher Ganser et al.   JOURNAL OF MEDICINAL CHEMISTRY

Asymmetric Hydrovinylation of Vinylindoles. A Facile Route to Cyclopenta[g]indole Natural Products (+)-cis-Trikentrin A and (+)-cis-Trikentrin B

(2012) Wang Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of amino-substituted indoles using the Bartoli reaction

(2012) Laura Wylie et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Total synthesis of (±)-cis-trikentrin B via intermolecular 6,7-indole aryne cycloaddition and Stille cross-coupling

(2012) Nalin Chandrasoma et al.   TETRAHEDRON LETTERS

Indole synthesis – something old, something new

(2012) Martyn Inman et al.   Chemical Science

Synthesis, structure–affinity relationships, and molecular modeling studies of novel pyrazolo[3,4-c]quinoline derivatives as adenosine receptor antagonists

(2011) Ombretta Lenzi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Benzimidazolone as potent chymase inhibitor: Modulation of reactive metabolite formation in the hydrophobic (P1) region

(2011) Ho Yin Lo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Green chemistry: solvent- and metal-free Prins cyclization. Application to sequential reactions

(2011) Damien Clarisse et al.   CHEMICAL COMMUNICATIONS

Update 1 of: Synthesis and Functionalization of Indoles Through Palladium-Catalyzed Reactions

(2011) Sandro Cacchi et al.   CHEMICAL REVIEWS

Microwave-Assisted Synthesis of Medicinally Relevant Indoles

(2011) S. A. Patil et al.   CURRENT MEDICINAL CHEMISTRY

Novel indole and azaindole (pyrrolopyridine) cannabinoid (CB) receptor agonists: Design, synthesis, structure–activity relationships, physicochemical properties and biological activity

(2011) Antoni R. Blaazer et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Recent advances in indole syntheses: New routes for a classic target

(2011) Rubén Vicente   ORGANIC & BIOMOLECULAR CHEMISTRY

Total Synthesis of (±)-Dragmacidin E

(2011) Ken S. Feldman et al.   ORGANIC LETTERS

Benzopyrrole derivatives as effective anion receptors in highly competitive solvents

(2011) Janusz Jurczak et al.   PURE AND APPLIED CHEMISTRY

4,7-Diaryl indole-based fluorescent chemosensor for iodide ions

(2011) Krishnaswamy R. Rathikrishnan et al.   TETRAHEDRON

Indole synthesis: a review and proposed classification

(2011) Douglass F. Taber et al.   TETRAHEDRON

Rapid synthesis of diversely functionalized 3,4,7-trisubstituted indoles

(2011) Seth W. Grant et al.   TETRAHEDRON LETTERS

Enantioselective rhodium-catalyzed arylation of electron-deficient alkenylarenes

(2011) Aakarsh Saxena et al.   Chemical Science

Potent inhibition of Ca2+-dependent activation of calpain-1 by novel mercaptoacrylates

(2011) Sarah E. Adams et al.   MedChemComm

Application of 6,7-Indole Aryne Cycloaddition and Pd(0)-Catalyzed Suzuki–Miyaura and Buchwald–Hartwig Cross-Coupling Reactions for the Preparation of Annulated Indole Libraries

(2011) Paul D. Thornton et al.   ACS Combinatorial Science

Novel 1H-pyrrolo[2,3-c]pyridines as acid pump antagonists (APAs)

(2010) Young Ae Yoon et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Site-Selective Cross-Coupling of Dichlorinated Benzo-Fused Nitrogen-Heterocycles with Grignard Reagents

(2010) Hideyuki Konishi et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Synthesis of Indole Derivatives with Biological Activity by Reactions Between Unsaturated Hydrocarbons and N-Aromatic Precursors

(2010) Giovanni Palmisano et al.   CURRENT ORGANIC CHEMISTRY

Annulated Diketopiperazines from Dipeptides or Schöllkopf Reagents via Tandem Cyclization−Intramolecular N-Arylation

(2010) Hwan Jung Lim et al.   ORGANIC LETTERS

Total syntheses of trikentrins and of herbindoles

(2010) Luiz F. Silva et al.   TETRAHEDRON

Catalytic Functionalization of Indoles in a New Dimension

(2009) Marco Bandini et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Evaluation of basic, heterocyclic ring systems as templates for use as potassium competitive acid blockers (pCABs)

(2009) Terry Panchal et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

First generation 5-vinyl-3-pyridinecarbonitrile PKCθ inhibitors

(2009) Chuansheng Niu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthetic Approach to Telomerase Inhibitor Dictyodendrin B: Synthesis of the Pyrrolo[2,3-c]carbazole Core

(2009) Shotaro HIRAO et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Anion receptors based on 7,7′-diamido-2,2′-diindolylmethane

(2009) Paweł Dydio et al.   CHEMICAL COMMUNICATIONS

Vinylation of Nitro-Substituted Indoles, Quinolinones, and Anilides with Grignard Reagents

(2009) Riccardo Egris et al.   CHEMISTRY-A EUROPEAN JOURNAL

Solid Phase Synthesis of Biologically Important Indoles

(2009) Shivaputra Patil et al.   CURRENT MEDICINAL CHEMISTRY

Discovery of 1-[4-(3-Chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridin-7-yl]-1-morpholin-4-ylmethanone (GSK554418A), a Brain Penetrant 5-Azaindole CB2Agonist for the Treatment of Chronic Pain

(2009) Gerard M. P. Giblin et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inhibitors of Human Immunodeficiency Virus Type 1 (HIV-1) Attachment. 5. An Evolution from Indole to Azaindoles Leading to the Discovery of 1-(4-Benzoylpiperazin-1-yl)-2-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-488043), a Drug Candidate That Demonstrates Antiviral Activity in HIV-1-Infected Subjects∞

(2009) Tao Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure−Activity Relationship Studies Leading to the Identification of (2E)-3-[l-[(2,4-Dichlorophenyl)methyl]-5-fluoro-3-methyl-lH-indol-7-yl]-N-[(4,5-dichloro-2-thienyl)sulfonyl]-2-propenamide (DG-041), a Potent and Selective Prostanoid EP3 Receptor Antagonist, as a Novel Antiplatelet Agent That Does Not Prolong Bleeding

(2009) Jasbir Singh et al.   JOURNAL OF MEDICINAL CHEMISTRY

Diels−Alder Reactions of Cyclopentadienones with Aryl Alkynes To Form Biaryl Compounds

(2009) Anthony J. Pearson et al.   JOURNAL OF ORGANIC CHEMISTRY

New synthesis of (±)-cis-trikentrin A via tandem indole aryne cycloaddition/Negishi reaction. Applications to library development

(2009) Neil Brown et al.   TETRAHEDRON LETTERS

Discovery of nonsteroidal glucocorticoid receptor ligands based on 6-indole-1,2,3,4-tetrahydroquinolines

(2008) Steven L. Roach et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A Diastereoselective Total Synthesis oftrans-Trikentrin A: A Ring Contraction Approach

(2008) Luiz F. Silva et al.   ORGANIC LETTERS

Concise Total Synthesis of (±)-cis-Trikentrin A and (±)-Herbindole A via Intermolecular Indole Aryne Cycloaddition

(2008) Keith R. Buszek et al.   ORGANIC LETTERS

Expedient routes to valuable bromo-5,6-dimethoxyindole building blocks

(2008) Paul B. Huleatt et al.   TETRAHEDRON LETTERS

Synthesis, structure and the binding properties of the amide-based anion receptors derived from 1H-indole-7-amine

(2007) Tomasz Zieliński et al.   TETRAHEDRON

A new and efficient one-pot synthesis of indoles

(2007) George Bratulescu   TETRAHEDRON LETTERS