Journal
TETRAHEDRON LETTERS
Volume 52, Issue 36, Pages 4681-4685Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2011.07.009
Keywords
Palladium; C-H activation; Indole; N-aryl amide; Alkyne
Categories
Funding
- Major State Basic Research Program [2009CB825300]
- National Natural Science Foundation of China [20732005, 20872158]
- Chinese Academy of Sciences
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A convenient and efficient method for the construction of indole skeleton was developed via Pd-catalyzed C-H activation of N-aryl amides and subsequent coupling with alkynes. Both stoichiometric and catalytic versions have been successfully achieved. (C) 2011 Elsevier Ltd. All rights reserved.
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