De NovoDesign of Functional Oligonucleotides with Acyclic Scaffolds

Light-Driven DNA Nanomachine with a Photoresponsive Molecular Engine

(2014) Yukiko Kamiya et al.   ACCOUNTS OF CHEMICAL RESEARCH

Challenging the future of siRNA therapeutics against cancer: the crucial role of nanotechnology

(2013) Lígia Catarina Gomes-da-Silva et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches

(2013) Wiktor Szymański et al.   CHEMICAL REVIEWS

Chemistry and formulations for siRNA therapeutics

(2013) Andrzej Gallas et al.   CHEMICAL SOCIETY REVIEWS

Highly Stable Duplex Formation by Artificial Nucleic Acids Acyclic Threoninol Nucleic Acid (aTNA) and Serinol Nucleic Acid (SNA) with Acyclic Scaffolds

(2013) Keiji Murayama et al.   CHEMISTRY-A EUROPEAN JOURNAL

Brightness Enhanced DNA FIT-Probes for Wash-Free RNA Imaging in Tissue

(2013) Felix Hövelmann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

p-Stilbazole Moieties As Artificial Base Pairs for Photo-Cross-Linking of DNA Duplex

(2013) Hiromu Kashida et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In-stem labelling allows visualization of DNA strand displacements by distinct fluorescent colour change

(2013) Sebastian Barrois et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Selective labeling of mature RISC using a siRNA carrying fluorophore–quencher pair

(2013) Yukiko Kamiya et al.   Chemical Science

Light-Controlled Tools

(2012) Clara Brieke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Structure of Human Argonaute-2 in Complex with miR-20a

(2012) Elad Elkayam et al.   CELL

Single Labeled DNA FIT Probes for Avoiding False-Positive Signaling in the Detection of DNA/RNA in qPCR or Cell Media

(2012) Felix Hövelmann et al.   CHEMBIOCHEM

Reversed Assembly of Dyes in an RNA Duplex Compared with Those in DNA

(2012) Taiga Fujii et al.   CHEMISTRY-A EUROPEAN JOURNAL

Bulge-like Asymmetric Heterodye Clustering in DNA Duplex Results in Efficient Quenching of Background Emission Based on the Maximized Excitonic Interaction

(2012) Taiga Fujii et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rational Design of Functional DNA with a Non-Ribose Acyclic Scaffold

(2012) Hiromu Kashida et al.   CURRENT ORGANIC CHEMISTRY

The Crystal Structure of Human Argonaute2

(2012) N. T. Schirle et al.   SCIENCE

Quencher-free linear probe with multiple fluorophores on an acyclic scaffold

(2012) Hiroyuki Asanuma et al.   Chemical Science

Recent trends in molecular beacon design and applications

(2011) Kewei Huang et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

In-Stem-Labeled Molecular Beacons for Distinct Fluorescent Color Readout

(2011) Carolin Holzhauser et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Control of the Chirality and Helicity of Oligomers of Serinol Nucleic Acid (SNA) by Sequence Design

(2011) Hiromu Kashida et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Photon-Fueled DNA Nanodevice that Contains Two Different Photoswitches

(2011) Hidenori Nishioka et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Improvement of RNAi Activity and Strand Selectivity of RISC Formation by Modified siRNA Involving Intercalators near 5′ Termini

(2011) Hiroshi Ito et al.   CHEMBIOCHEM

Detection of three-base deletion by exciplex formation with perylene derivatives

(2011) Hiromu Kashida et al.   CHEMICAL COMMUNICATIONS

A polycation-chaperoned in-stem molecular beacon system

(2011) Hiroyuki Asanuma et al.   CHEMICAL COMMUNICATIONS

A Cationic Dye Triplet as a Unique “Glue” That Can Connect Fully Matched Termini of DNA Duplexes

(2011) Hiromu Kashida et al.   CHEMISTRY-A EUROPEAN JOURNAL

4,4-Difluoro-4-bora-3a,4a-diaza-s-indacene as a Bright Fluorescent Label for DNA

(2011) Thomas Ehrenschwender et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis and Characterization of Conformationally Preorganized, (R)-Diethylene Glycol-Containing γ-Peptide Nucleic Acids with Superior Hybridization Properties and Water Solubility

(2011) Bichismita Sahu et al.   JOURNAL OF ORGANIC CHEMISTRY

Coherent Quenching of a Fluorophore for the Design of a Highly Sensitive In-Stem Molecular Beacon

(2010) Yuichi Hara et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Effect of theorthoModification of Azobenzene on the Photoregulatory Efficiency of DNA Hybridization and the Thermal Stability of itscisForm

(2010) Hidenori Nishioka et al.   CHEMISTRY-A EUROPEAN JOURNAL

Accumulation of Fluorophores into DNA Duplexes To Mimic the Properties of Quantum Dots

(2010) Hiromu Kashida et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oligopyrenotides: Abiotic, Polyanionic Oligomers with Nucleic Acid-like Structural Properties

(2010) Robert Häner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unexpectedly Stable Artificial Duplex from Flexible Acyclic Threoninol

(2010) Hiroyuki Asanuma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Designed thiazole orange nucleotides for the synthesis of single labelled oligonucleotides that fluoresce upon matched hybridization

(2010) Lucas Bethge et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Making RISC

(2010) Tomoko Kawamata et al.   TRENDS IN BIOCHEMICAL SCIENCES

In-Stem Molecular Beacon Containing a Pseudo Base Pair of Threoninol Nucleotides for the Removal of Background Emission

(2009) Hiromu Kashida et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Light-Activated DNA Polymerase

(2009) Chungjung Chou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Exciton-Controlled Hybridization-Sensitive Fluorescent Probes: Multicolor Detection of Nucleic Acids

(2009) Shuji Ikeda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Analysis of Coherent Heteroclustering of Different Dyes by Use of Threoninol Nucleotides for Comparison with the Molecular Exciton Theory

(2009) Taiga Fujii et al.   CHEMISTRY-A EUROPEAN JOURNAL

An interstrand-wedged duplex composed of alternating DNAbase pairs and covalently attached intercalators

(2009) Xingguo Liang et al.   JOURNAL OF MATERIALS CHEMISTRY

Positively Charged Base Surrogate for Highly Stable “Base Pairing” through Electrostatic and Stacking Interactions

(2009) Hiromu Kashida et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Supra-photoswitch Involving Sandwiched DNA Base Pairs and Azobenzenes for Light-Driven Nanostructures and Nanodevices

(2009) Xingguo Liang et al.   Small

Low-Noise Stemless PNA Beacons for Sensitive DNA and RNA Detection

(2008) Elke Socher et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Perylene Bisimide Dimers as Fluorescent “Glue” for DNA and for Base-Mismatch Detection

(2008) Daniela Baumstark et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Perylene Attached to 2′-Amino-LNA: Synthesis, Incorporation into Oligonucleotides, and Remarkable Fluorescence Propertiesin Vitroand in Cell Culture

(2008) Irina V. Astakhova et al.   BIOCONJUGATE CHEMISTRY

Threoninol as a scaffold of dyes (threoninol-nucleotide) and their stable interstrand clustering in duplexes

(2008) Hiromu Kashida et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Argonaute proteins: key players in RNA silencing

(2007) Gyorgy Hutvagner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY