Chikungunya virus non-structural protein 2-mediated host shut-off disables the unfolded protein response

Functional Cross-talk between Distant Domains of Chikungunya Virus Non-structural Protein 2 Is Decisive for Its RNA-modulating Activity

(2014) Pratyush Kumar Das et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CCR2 Deficiency Promotes Exacerbated Chronic Erosive Neutrophil-Dominated Chikungunya Virus Arthritis

(2014) Y. S. Poo et al.   JOURNAL OF VIROLOGY

Chikungunya in the Americas

(2014) Isabelle Leparc-Goffart et al.   LANCET

Chemical Derivatives of a Small Molecule Deubiquitinase Inhibitor Have Antiviral Activity against Several RNA Viruses

(2014) Marta J. Gonzalez-Hernandez et al.   PLoS One

First case of locally acquired chikungunya is reported in US

(2014) M. McCarthy   BMJ-British Medical Journal

A new paradigm: innate immune sensing of viruses via the unfolded protein response

(2014) Judith A. Smith   Frontiers in Microbiology

The C-Terminal Domain of Chikungunya Virus nsP2 Independently Governs Viral RNA Replication, Cytopathicity, and Inhibition of Interferon Signaling

(2013) J. J. Fros et al.   JOURNAL OF VIROLOGY

Characterization of Synthetic Chikungunya Viruses Based on the Consensus Sequence of Recent E1-226V Isolates

(2013) Florine E. M. Scholte et al.   PLoS One

Differential unfolded protein response during Chikungunya and Sindbis virus infection: CHIKV nsP4 suppresses eIF2α phosphorylation

(2013) Abhay P S Rathore et al.   Virology Journal

Effective Chikungunya Virus-like Particle Vaccine Produced in Insect Cells

(2013) Stefan W. Metz et al.   PLoS Neglected Tropical Diseases

Gene regulatory network of unfolded protein response genes in endoplasmic reticulum stress

(2012) Sayuri Takayanagi et al.   CELL STRESS & CHAPERONES

Herpes simplex virus-1 disarms the unfolded protein response in the early stages of infection

(2012) Heather F. Burnett et al.   CELL STRESS & CHAPERONES

Mapping of Chikungunya Virus Interactions with Host Proteins Identified nsP2 as a Highly Connected Viral Component

(2012) M. Bourai et al.   JOURNAL OF VIROLOGY

Interferon Response Factors 3 and 7 Protect against Chikungunya Virus Hemorrhagic Fever and Shock

(2012) Penny A. Rudd et al.   JOURNAL OF VIROLOGY

Evasion of the Innate Immune Response: the Old World Alphavirus nsP2 Protein Induces Rapid Degradation of Rpb1, a Catalytic Subunit of RNA Polymerase II

(2012) I. Akhrymuk et al.   JOURNAL OF VIROLOGY

Arthritogenic alphaviruses—an overview

(2012) Andreas Suhrbier et al.   Nature Reviews Rheumatology

Antiviral Activity of a Small Molecule Deubiquitinase Inhibitor Occurs via Induction of the Unfolded Protein Response

(2012) Jeffrey W. Perry et al.   PLoS Pathogens

Functional processing and secretion of Chikungunya virus E1 and E2 glycoproteins in insect cells

(2011) Stefan W Metz et al.   Virology Journal

Respiratory Syncytial Virus Limits α Subunit of Eukaryotic Translation Initiation Factor 2 (eIF2α) Phosphorylation to Maintain Translation and Viral Replication

(2010) Dayna J. Groskreutz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chikungunya Virus Arthritis in Adult Wild-Type Mice

(2010) J. Gardner et al.   JOURNAL OF VIROLOGY

Semliki Forest Virus-Induced Endoplasmic Reticulum Stress Accelerates Apoptotic Death of Mammalian Cells

(2010) G. Barry et al.   JOURNAL OF VIROLOGY

Chikungunya Virus Nonstructural Protein 2 Inhibits Type I/II Interferon-Stimulated JAK-STAT Signaling

(2010) Jelke J. Fros et al.   JOURNAL OF VIROLOGY

West Nile Virus Differentially Modulates the Unfolded Protein Response To Facilitate Replication and Immune Evasion

(2010) R. L. Ambrose et al.   JOURNAL OF VIROLOGY

Chikungunya Virus Induces IPS-1-Dependent Innate Immune Activation and Protein Kinase R-Independent Translational Shutoff

(2010) L. K. White et al.   JOURNAL OF VIROLOGY

A structural and functional perspective of alphavirus replication and assembly

(2009) Joyce Jose et al.   Future Microbiology

Stress-sensing mechanisms in the unfolded protein response: similarities and differences between yeast and mammals

(2009) K. Kohno   JOURNAL OF BIOCHEMISTRY

An improved in vitro and in vivo Sindbis virus expression system through host and virus engineering

(2009) Toey Nivitchanyong et al.   VIRUS RESEARCH

Mutations in the nuclear localization signal of nsP2 influencing RNA synthesis, protein expression and cytotoxicity of Semliki Forest virus

(2008) K. Tamm et al.   JOURNAL OF GENERAL VIROLOGY

From endoplasmic-reticulum stress to the inflammatory response

(2008) Kezhong Zhang et al.   NATURE