Antiviral Activity of a Small Molecule Deubiquitinase Inhibitor Occurs via Induction of the Unfolded Protein Response

Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis

(2011) H. Sun et al.   BLOOD

DUBs and cancer: The role of deubiquitinating enzymes as oncogenes, non-oncogenes and tumor suppressors

(2011) Sajjad Hussain et al.   CELL CYCLE

Unspecified Gastroenteritis Illness and Deaths in the Elderly Associated With Norovirus Epidemics

(2011) Liselotte van Asten et al.   EPIDEMIOLOGY

The Cell Biology of the Unfolded Protein Response

(2011) J. Alan Diehl et al.   GASTROENTEROLOGY

A Small Molecule Deubiquitinase Inhibitor Increases Localization of Inducible Nitric Oxide Synthase to the Macrophage Phagosome and Enhances Bacterial Killing

(2011) Kristin M. Burkholder et al.   INFECTION AND IMMUNITY

Economic Impact of Outbreaks of Norovirus Infection in Hospitals

(2011) Bruce Y. Lee et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Unfolded protein response in cancer: the Physician's perspective

(2011) Xuemei Li et al.   Journal of Hematology & Oncology

Rotavirus Infection Induces the Unfolded Protein Response of the Cell and Controls It through the Nonstructural Protein NSP3

(2011) V. Trujillo-Alonso et al.   JOURNAL OF VIROLOGY

Rotavirus infection activates the UPR but modulates its activity

(2011) Jose Zambrano et al.   Virology Journal

Deubiquitinase Inhibition by Small-Molecule WP1130 Triggers Aggresome Formation and Tumor Cell Apoptosis

(2010) V. Kapuria et al.   CANCER RESEARCH

Ubiquitination and deubiquitination of NP protein regulates influenza A virus RNA replication

(2010) Tsai-Ling Liao et al.   EMBO JOURNAL

Bifunctional Apoptosis Regulator (BAR), an Endoplasmic Reticulum (ER)-associated E3 Ubiquitin Ligase, Modulates BI-1 Protein Stability and Function in ER Stress

(2010) Juan Rong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro

(2010) Po-Yuan Ke et al.   JOURNAL OF CLINICAL INVESTIGATION

Human Neuronal Cells Possess Functional Cytoplasmic and TLR-Mediated Innate Immune Pathways Influenced by Phosphatidylinositol-3 Kinase Signaling

(2010) D. C. Peltier et al.   JOURNAL OF IMMUNOLOGY

Endocytosis of Murine Norovirus 1 into Murine Macrophages Is Dependent on Dynamin II and Cholesterol

(2010) J. W. Perry et al.   JOURNAL OF VIROLOGY

West Nile Virus Differentially Modulates the Unfolded Protein Response To Facilitate Replication and Immune Evasion

(2010) R. L. Ambrose et al.   JOURNAL OF VIROLOGY

Trimming of Ubiquitin Chains by Proteasome-associated Deubiquitinating Enzymes

(2010) Min Jae Lee et al.   MOLECULAR & CELLULAR PROTEOMICS

Enhancement of proteasome activity by a small-molecule inhibitor of USP14

(2010) Byung-Hoon Lee et al.   NATURE

Norwalk virus does not replicate in human macrophages or dendritic cells derived from the peripheral blood of susceptible humans

(2010) Margarita K. Lay et al.   VIROLOGY

Noroviruses: State of the Art

(2010) Robert L. Atmar   Food and Environmental Virology

The ubiquitin proteasome system in neuropathology

(2009) Norman L. Lehman   ACTA NEUROPATHOLOGICA

Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes

(2009) Francisca E. Reyes-Turcu et al.   Annual Review of Biochemistry

Recognition and Processing of Ubiquitin-Protein Conjugates by the Proteasome

(2009) Daniel Finley   Annual Review of Biochemistry

Effects of hepatitis C virus envelope glycoprotein unfolded protein response activation on translation and transcription

(2009) Shiu-Wan Chan et al.   ARCHIVES OF VIROLOGY

USP14 inhibits ER-associated degradation via interaction with IRE1α

(2009) Atsushi Nagai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Virus-Induced Unfolded Protein Response Attenuates Antiviral Defenses via Phosphorylation-Dependent Degradation of the Type I Interferon Receptor

(2009) Jianghuai Liu et al.   Cell Host & Microbe

Ubiquitination, Ubiquitin-like Modifiers, and Deubiquitination in Viral Infection

(2009) Marisa K. Isaacson et al.   Cell Host & Microbe

Role of Cholesterol Pathways in Norovirus Replication

(2009) K.-O. Chang   JOURNAL OF VIROLOGY

Mouse Norovirus Replication Is Associated with Virus-Induced Vesicle Clusters Originating from Membranes Derived from the Secretory Pathway

(2009) J. L. Hyde et al.   JOURNAL OF VIROLOGY

Ganglioside-Linked Terminal Sialic Acid Moieties on Murine Macrophages Function as Attachment Receptors for Murine Noroviruses

(2009) S. Taube et al.   JOURNAL OF VIROLOGY

Hepatitis C virus NS4B induces unfolded protein response and endoplasmic reticulum overload response-dependent NF-κB activation

(2009) Shanshan Li et al.   VIROLOGY

An improved in vitro and in vivo Sindbis virus expression system through host and virus engineering

(2009) Toey Nivitchanyong et al.   VIRUS RESEARCH

Murine norovirus-1 entry into permissive macrophages and dendritic cells is pH-independent

(2009) Jeffrey W. Perry et al.   VIRUS RESEARCH

The ubiquitin system, disease, and drug discovery

(2008) Matthew D Petroski   BMC BIOCHEMISTRY

Progress in understanding norovirus epidemiology

(2008) Marion Koopmans   CURRENT OPINION IN INFECTIOUS DISEASES

Synoviolin promotes IRE1 ubiquitination and degradation in synovial fibroblasts from mice with collagen-induced arthritis

(2008) Beixue Gao et al.   EMBO REPORTS