Chemical Derivatives of a Small Molecule Deubiquitinase Inhibitor Have Antiviral Activity against Several RNA Viruses

Identification of a Broad-Spectrum Inhibitor of Viral RNA Synthesis: Validation of a Prototype Virus-Based Approach

(2013) Claire Marie Filone et al.   CHEMISTRY & BIOLOGY

A Mouse Model for Human Norovirus

(2013) S. Taube et al.   mBio

Targeting Host Factors to Circumvent Anti-Malarial Drug Resistance

(2012) Miguel Prudencio et al.   CURRENT PHARMACEUTICAL DESIGN

Antiviral therapy: old and current issues

(2012) Guido Antonelli et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Experimental Inoculation of Juvenile Rhesus Macaques with Primate Enteric Caliciviruses

(2012) Karol Sestak et al.   PLoS One

The distinct contributions of fitness and genetic barrier to the development of antiviral drug resistance

(2012) Matthias Götte   Current Opinion in Virology

Antiviral Activity of a Small Molecule Deubiquitinase Inhibitor Occurs via Induction of the Unfolded Protein Response

(2012) Jeffrey W. Perry et al.   PLoS Pathogens

Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis

(2011) H. Sun et al.   BLOOD

Unspecified Gastroenteritis Illness and Deaths in the Elderly Associated With Norovirus Epidemics

(2011) Liselotte van Asten et al.   EPIDEMIOLOGY

A Small Molecule Deubiquitinase Inhibitor Increases Localization of Inducible Nitric Oxide Synthase to the Macrophage Phagosome and Enhances Bacterial Killing

(2011) Kristin M. Burkholder et al.   INFECTION AND IMMUNITY

Economic Impact of Outbreaks of Norovirus Infection in Hospitals

(2011) Bruce Y. Lee et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Potent Host-Directed Small-Molecule Inhibitors of Myxovirus RNA-Dependent RNA-Polymerases

(2011) Stefanie A. Krumm et al.   PLoS One

Identification of broad-spectrum antiviral compounds and assessment of the druggability of their target for efficacy against respiratory syncytial virus (RSV)

(2011) A. Bonavia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis

(2011) H.-H. Hoffmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Dynamics of Norovirus Outbreak Epidemics: Recent Insights

(2011) John A. Marshall et al.   International Journal of Environmental Research and Public Health

Deubiquitinase Inhibition by Small-Molecule WP1130 Triggers Aggresome Formation and Tumor Cell Apoptosis

(2010) V. Kapuria et al.   CANCER RESEARCH

Human Neuronal Cells Possess Functional Cytoplasmic and TLR-Mediated Innate Immune Pathways Influenced by Phosphatidylinositol-3 Kinase Signaling

(2010) D. C. Peltier et al.   JOURNAL OF IMMUNOLOGY

Noroviruses: State of the Art

(2010) Robert L. Atmar   Food and Environmental Virology

Debio-025 inhibits HIV-1 by interfering with an early event in the replication cycle

(2009) Dirk Daelemans et al.   ANTIVIRAL RESEARCH

Ubiquitination, Ubiquitin-like Modifiers, and Deubiquitination in Viral Infection

(2009) Marisa K. Isaacson et al.   Cell Host & Microbe

Detection of norovirus-, sapovirus- and rhesus enteric calicivirus-specific antibodies in captive juvenile macaques

(2009) T. Farkas et al.   JOURNAL OF GENERAL VIROLOGY

Conservation of Carbohydrate Binding Interfaces — Evidence of Human HBGA Selection in Norovirus Evolution

(2009) Ming Tan et al.   PLoS One

Characterization of a Rhesus Monkey Calicivirus Representing a New Genus of Caliciviridae

(2008) T. Farkas et al.   JOURNAL OF VIROLOGY

Host-Directed Drug Targeting of Factors Hijacked by Pathogens

(2008) A. Schwegmann et al.   Science Signaling