From General to Specific: Can Pseudomonas Primary Metabolism Be Exploited for Narrow-Spectrum Antibiotics?

Promysalin Elicits Species-Selective Inhibition of Pseudomonas aeruginosa by Targeting Succinate Dehydrogenase

(2018) Colleen E. Keohane et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Small Molecules That Sabotage Bacterial Virulence

(2017) Benjamin K. Johnson et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

One ligand, two regulators and three binding sites: How KDPG controls primary carbon metabolism in Pseudomonas

(2017) Rosaria Campilongo et al.   PLoS Genetics

Diverted Total Synthesis of Promysalin Analogs Demonstrates That an Iron-Binding Motif Is Responsible for Its Narrow-Spectrum Antibacterial Activity

(2016) Andrew D. Steele et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cystic fibrosis lung environment and Pseudomonas aeruginosa infection

(2016) Anjali Y. Bhagirath et al.   BMC Pulmonary Medicine

The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation

(2016) Amy Langdon et al.   Genome Medicine

Chronic wound infections: the role ofPseudomonas aeruginosaandStaphylococcus aureus

(2015) Raffaele Serra et al.   Expert Review of Anti-Infective Therapy

Pseudomonas putidaKT2440 Strain Metabolizes Glucose through a Cycle Formed by Enzymes of the Entner-Doudoroff, Embden-Meyerhof-Parnas, and Pentose Phosphate Pathways

(2015) Pablo I. Nikel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Total Synthesis and Biological Investigation of (−)-Promysalin

(2015) Andrew D. Steele et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Rhizosphere Microbiome: A Playground for Natural Product Chemists

(2015) William Wuest et al.   SYNLETT

Robustness and Plasticity of Metabolic Pathway Flux among Uropathogenic Isolates of Pseudomonas aeruginosa

(2014) Antje Berger et al.   PLoS One

Platforms for antibiotic discovery

(2013) Kim Lewis   NATURE REVIEWS DRUG DISCOVERY

Catabolite repression inPseudomonas aeruginosa PAO1 regulates the uptake of C4-dicarboxylates depending on succinate concentration

(2012) Martina Valentini et al.   ENVIRONMENTAL MICROBIOLOGY

The Entner-Doudoroff pathway empowersPseudomonas putida KT2440 with a high tolerance to oxidative stress

(2012) Max Chavarría et al.   ENVIRONMENTAL MICROBIOLOGY

Rethinking glycolysis: on the biochemical logic of metabolic pathways

(2012) Arren Bar-Even et al.   Nature Chemical Biology

Regulatory Tasks of the Phosphoenolpyruvate-Phosphotransferase System of Pseudomonas putida in Central Carbon Metabolism

(2012) M. Chavarria et al.   mBio

Promysalin, a Salicylate-Containing Pseudomonas putida Antibiotic, Promotes Surface Colonization and Selectively Targets Other Pseudomonas

(2011) Wen Li et al.   CHEMISTRY & BIOLOGY

Siccanin Rediscovered as a Species-Selective Succinate Dehydrogenase Inhibitor

(2009) T. Mogi et al.   JOURNAL OF BIOCHEMISTRY