Resveratrol and Health: The Starting Point

Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1α in skeletal muscle

(2016) Orsolya M. Palacios et al.   Aging-US

Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases

(2012) Sung-Jun Park et al.   CELL

Sirtuins mediate mammalian metabolic responses to nutrient availability

(2012) Angeliki Chalkiadaki et al.   Nature Reviews Endocrinology

Anti-diabetic effects of resveratrol

(2011) Tomasz Szkudelski et al.   Annals of the New York Academy of Sciences

Resveratrol and life extension

(2011) Beamon Agarwal et al.   Annals of the New York Academy of Sciences

Clinical trials of resveratrol

(2011) Ketan R. Patel et al.   Annals of the New York Academy of Sciences

Bioavailability of resveratrol

(2011) Thomas Walle   Annals of the New York Academy of Sciences

Polyphenols and Human Health: A Prospectus

(2011) Francesco Visioli et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Understanding anomalous adaptation in chronic pain for successful development of disease modifying drugs

(2011) Giacinto Bagetta et al.   CURRENT OPINION IN PHARMACOLOGY

The controversial links among calorie restriction, SIRT1, and resveratrol

(2011) Yi Hu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Rap1 GTPases: An emerging role in the cardiovasculature

(2011) Selvi C. Jeyaraj et al.   LIFE SCIENCES

Modulatory effect of resveratrol on SIRT1, SIRT3, SIRT4, PGC1α and NAMPT gene expression profiles in wild-type adult zebrafish liver

(2011) Helena Schirmer et al.   MOLECULAR BIOLOGY REPORTS

The SirT3 Divining Rod Points to Oxidative Stress

(2011) Eric L. Bell et al.   MOLECULAR CELL

Resveratrol and health - A comprehensive review of human clinical trials

(2011) James M. Smoliga et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

(2011) Camilla Burnett et al.   NATURE

Aging Genes: The Sirtuin Story Unravels

(2011) J. Couzin-Frankel   SCIENCE

Aging and disease: connections to sirtuins

(2010) Gizem Donmez et al.   AGING CELL

Regulation of SIRT1 in cellular functions: Role of polyphenols

(2010) Sangwoon Chung et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Interdependence of AMPK and SIRT1 for Metabolic Adaptation to Fasting and Exercise in Skeletal Muscle

(2010) Carles Cantó et al.   Cell Metabolism

AMP-activated protein kinase and its downstream transcriptional pathways

(2010) Carles Cantó et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Genistein, a competitive PDE1–4 inhibitor, may bind on high-affinity rolipram binding sites of brain cell membranes and then induce gastrointestinal adverse effects

(2010) Chung-Hong Shih et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

AMP-activated Protein Kinase Signaling Activation by Resveratrol Modulates Amyloid-β Peptide Metabolism

(2010) Valérie Vingtdeux et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT1 contributes to telomere maintenance and augments global homologous recombination

(2010) Jose A. Palacios et al.   JOURNAL OF CELL BIOLOGY

Hydrogen peroxide inhibits mTOR signaling by activation of AMPKα leading to apoptosis of neuronal cells

(2010) Long Chen et al.   LABORATORY INVESTIGATION

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

(2009) Carles Cantó et al.   CURRENT OPINION IN LIPIDOLOGY

AMP-Activated Protein Kinase-Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol

(2009) J.-H. Um et al.   DIABETES

Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio

(2009) Brooke M. Emerling et al.   FREE RADICAL BIOLOGY AND MEDICINE

Quantification of trans-resveratrol and its metabolites in rat plasma and tissues by HPLC

(2009) M. Emília Juan et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Resveratrol Protects Mitochondria against Oxidative Stress through AMP-Activated Protein Kinase-Mediated Glycogen Synthase Kinase-3  Inhibition Downstream of Poly(ADP-ribose)polymerase-LKB1 Pathway

(2009) S. M. Shin et al.   MOLECULAR PHARMACOLOGY

Treatment with the phosphodiesterase type-4 inhibitor rolipram fails to inhibit blood—brain barrier disruption in multiple sclerosis

(2009) Bibiana Bielekova et al.   Multiple Sclerosis Journal

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE