SIRT1 contributes to telomere maintenance and augments global homologous recombination

SIRT1: roles in aging and cancer

(2011) Eun-Joo Kim et al.   BMB Reports

Role of SIRT1 in homologous recombination

(2010) Miriam Uhl et al.   DNA REPAIR

Open for business

(2010)   Nature Communications

Aging and cancer cell biology, 2009

(2009) Judith Campisi et al.   AGING CELL

Treatment with SRT1720, a SIRT1 activator, ameliorates fatty liver with reduced expression of lipogenic enzymes in MSG mice

(2009) Yu Yamazaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication

(2009) Agnel Sfeir et al.   CELL

Telomeres Acquire Embryonic Stem Cell Characteristics in Induced Pluripotent Stem Cells

(2009) Rosa M. Marion et al.   Cell Stem Cell

Functional interplay between Parp-1 and SirT1 in genome integrity and chromatin-based processes

(2009) Rosy El Ramy et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cellular Regulation of SIRT1

(2009) Jo Milner   CURRENT PHARMACEUTICAL DESIGN

Silent chromatin at the middle and ends: lessons from yeasts

(2009) Marc Bühler et al.   EMBO JOURNAL

Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction

(2009) D. E. Cohen et al.   GENES & DEVELOPMENT

Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice

(2009) P. Martinez et al.   GENES & DEVELOPMENT

In VivoStoichiometry of Shelterin Components

(2009) Kaori K. Takai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol induces senescence-like growth inhibition of U-2 OS cells associated with the instability of telomeric DNA and upregulation of BRCA1

(2009) Marek Rusin et al.   MECHANISMS OF AGEING AND DEVELOPMENT

CBP/p300-mediated acetylation of histone H3 on lysine 56

(2009) Chandrima Das et al.   NATURE

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

(2009) Rosa M. Marión et al.   NATURE

SIRT1 and insulin resistance

(2009) Fengxia Liang et al.   Nature Reviews Endocrinology

Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuins

(2009) Ivy K. M. Law et al.   PROTEOMICS

Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1

(2009) S. D. Westerheide et al.   SCIENCE

CELL BIOLOGY: Stress Response and Aging

(2009) L. R. Saunders et al.   SCIENCE

How Telomeres Solve the End-Protection Problem

(2009) T. de Lange   SCIENCE

Caloric restriction, SIRT1 and longevity

(2009) Carles Cantó et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice

(2008) Rui-Hong Wang et al.   CANCER CELL

Telomerase Reverse Transcriptase Delays Aging in Cancer-Resistant Mice

(2008) Antonia Tomás-Loba et al.   CELL

SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging

(2008) Philipp Oberdoerffer et al.   CELL

Acetylated Lysine 56 on Histone H3 Drives Chromatin Assembly after Repair and Signals for the Completion of Repair

(2008) Chin-Chuan Chen et al.   CELL

Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span

(2008) Kevin J. Pearson et al.   Cell Metabolism

Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic Disorders by Enhancing Fat Oxidation

(2008) Jérôme N. Feige et al.   Cell Metabolism

Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt

(2008) Marcella Fulco et al.   DEVELOPMENTAL CELL

Sirtuin-mediated deacetylation pathway stabilizes Werner syndrome protein

(2008) Tomoaki Kahyo et al.   FEBS LETTERS

The longest telomeres: a general signature of adult stem cell compartments

(2008) I. Flores et al.   GENES & DEVELOPMENT

Regulation of WRN Protein Cellular Localization and Enzymatic Activities by SIRT1-mediated Deacetylation

(2008) Kai Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Centromere mitotic recombination in mammalian cells

(2008) Isabel Jaco et al.   JOURNAL OF CELL BIOLOGY

Increased telomerase activity and comprehensive lifestyle changes: a pilot study

(2008) Dean Ornish et al.   LANCET ONCOLOGY

SIRT1 Acts as a Nutrient-sensitive Growth Suppressor and Its Loss Is Associated with Increased AMPK and Telomerase Activity

(2008) Swami R. Narala et al.   MOLECULAR BIOLOGY OF THE CELL

Sirt1 contributes critically to the redox-dependent fate of neural progenitors

(2008) Timour Prozorovski et al.   NATURE CELL BIOLOGY

SirT1 Regulates Energy Metabolism and Response to Caloric Restriction in Mice

(2008) Gino Boily et al.   PLoS One

Sirt1 Deficiency Attenuates Spermatogenesis and Germ Cell Function

(2008) Matthew Coussens et al.   PLoS One

Sirt1 protects against high-fat diet-induced metabolic damage

(2008) P. T. Pfluger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Telomere exchange and asymmetric segregation of chromosomes can account for the unlimited proliferative potential of ALT cell populations

(2007) Krastan B. Blagoev et al.   DNA REPAIR