Modulation of NF-κB signalling by microbial pathogens

Salmonella Secreted Factor L Deubiquitinase of Salmonella typhimurium Inhibits NF- B, Suppresses I B  Ubiquitination and Modulates Innate Immune Responses

(2014) G. Le Negrate et al.   JOURNAL OF IMMUNOLOGY

NFκB inhibitors: Strategies from poxviruses

(2011) Mohamed Ragaa Mohamed et al.   CELL CYCLE

Activation of Noncanonical NF-κB Signaling by the Oncoprotein Tio

(2010) Sarah Jill de Jong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations in modified virus Ankara protein 183 render it a non-functional counterpart of B14, an inhibitor of nuclear factor  B activation

(2010) L. E. McCoy et al.   JOURNAL OF GENERAL VIROLOGY

Bovine viral diarrhea virus non-structural protein 5A interacts with NIK- and IKK -binding protein

(2010) M. A. Zahoor et al.   JOURNAL OF GENERAL VIROLOGY

NF- B RelA Subunit Is Crucial for Early IFN-  Expression and Resistance to RNA Virus Replication

(2010) J. Wang et al.   JOURNAL OF IMMUNOLOGY

The N Terminus of Adenovirus Type 12 E1A Inhibits Major Histocompatibility Complex Class I Expression by Preventing Phosphorylation of NF- B p65 Ser276 through Direct Binding

(2010) J. Jiao et al.   JOURNAL OF VIROLOGY

Viral Cell Death Inhibitor MC159 Enhances Innate Immunity against Vaccinia Virus Infection

(2010) Sreerupa Challa et al.   JOURNAL OF VIROLOGY

Epstein-Barr Virus Latent Membrane Protein 1 Modulates Distinctive NF- B Pathways through C-Terminus-Activating Region 1 To Regulate Epidermal Growth Factor Receptor Expression

(2010) C.-P. Kung et al.   JOURNAL OF VIROLOGY

A Novel Inhibitor of the NF- B Signaling Pathway Encoded by the Parapoxvirus Orf Virus

(2010) D. G. Diel et al.   JOURNAL OF VIROLOGY

Respiratory Syncytial Virus-Mediated NF- B p65 Phosphorylation at Serine 536 Is Dependent on RIG-I, TRAF6, and IKK 

(2010) F. Yoboua et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus Immediate-Early ICP0 Protein Inhibits Toll-Like Receptor 2-Dependent Inflammatory Responses and NF-κB Signaling

(2010) Allison L. van Lint et al.   JOURNAL OF VIROLOGY

Epstein-Barr virus-encoded EBNA1 inhibits the canonical NF-κB pathway in carcinoma cells by inhibiting IKK phosphorylation

(2010) Robert Valentine et al.   Molecular Cancer

Regulation of NF-κB inhibitor IκBα and viral replication by a KSHV microRNA

(2010) Xiufen Lei et al.   NATURE CELL BIOLOGY

NF-κB signaling modulation by EBV and KSHV

(2010) Deilson Elgui de Oliveira et al.   TRENDS IN MICROBIOLOGY

BFV activates the NF-κB pathway through its transactivator (BTas) to enhance viral transcription

(2010) Jian Wang et al.   VIROLOGY

Roles of TRAF2 and TRAF3 in Epstein-Barr virus latent membrane protein 1-induced alternative NF-κB activation

(2010) Yoon-Jae Song et al.   VIRUS GENES

The IKK Kinases: Operators of Antiviral Signaling

(2010) Alissa Pham et al.   Viruses-Basel

The Type III Secretion Effector NleE Inhibits NF-κB Activation

(2010) Chen Nadler et al.   PLoS Pathogens

The Type III Effectors NleE and NleB from Enteropathogenic E. coli and OspZ from Shigella Block Nuclear Translocation of NF-κB p65

(2010) Hayley J. Newton et al.   PLoS Pathogens

Murine Gamma-Herpesvirus 68 Hijacks MAVS and IKKβ to Initiate Lytic Replication

(2010) Xiaonan Dong et al.   PLoS Pathogens

HIV-1 Tat dysregulation of lipopolysaccharide-induced cytokine responses: microbial interactions in HIV infection

(2009) Howard CH Yim et al.   AIDS

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

Protein secretion systems in bacterial-host associations, and their description in the Gene Ontology

(2009) Tsai-Tien Tseng et al.   BMC MICROBIOLOGY

Shigella Induces Mitochondrial Dysfunction and Cell Death in Nonmyleoid Cells

(2009) Leticia A.M. Carneiro et al.   Cell Host & Microbe

The nuclear signaling of NF-κB: current knowledge, new insights and future perspectives

(2009) Fengyi Wan et al.   CELL RESEARCH

A protein secreted by the respiratory pathogenChlamydia pneumoniaeimpairs IL-17 signalling via interaction with human Act1

(2009) Katerina Wolf et al.   CELLULAR MICROBIOLOGY

Effector protein modulation of host cells: examples in the Chlamydia spp. arsenal

(2009) Helen J Betts et al.   CURRENT OPINION IN MICROBIOLOGY

The roles of TLRs, RLRs and NLRs in pathogen recognition

(2009) T. Kawai et al.   INTERNATIONAL IMMUNOLOGY

The role of innate signaling in the homeostasis of tolerance and immunity in the intestine

(2009) Jerry M. Wells et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

HTLV-1 Tax Is a Critical Lipid Raft Modulator That Hijacks IκB Kinases to the Microdomains for Persistent Activation of NF-κB

(2009) Jiannan Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bordetellaevades the host immune system by inducing IL-10 through a type III effector, BopN

(2009) Kanna Nagamatsu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Poxvirus MC160 Protein Utilizes Multiple Mechanisms To Inhibit NF- B Activation Mediated via Components of the Tumor Necrosis Factor Receptor 1 Signal Transduction Pathway

(2009) D. B. Nichols et al.   JOURNAL OF VIROLOGY

Cowpox Virus Expresses a Novel Ankyrin Repeat NF- B Inhibitor That Controls Inflammatory Cell Influx into Virus-Infected Tissues and Is Critical for Virus Pathogenesis

(2009) M. R. Mohamed et al.   JOURNAL OF VIROLOGY

Vaccinia Virus K1L and C7L Inhibit Antiviral Activities Induced by Type I Interferons

(2009) X. Meng et al.   JOURNAL OF VIROLOGY

Poxvirus Host Range Protein CP77 Contains an F-Box-Like Domain That Is Necessary To Suppress NF- B Activation by Tumor Necrosis Factor Alpha but Is Independent of Its Host Range Function

(2009) S.-J. Chang et al.   JOURNAL OF VIROLOGY

Vaccinia Virus E3 Suppresses Expression of Diverse Cytokines through Inhibition of the PKR, NF- B, and IRF3 Pathways

(2009) C. Myskiw et al.   JOURNAL OF VIROLOGY

Enterohaemorrhagic Escherichia coli serogroup O111 inhibits NF- B-dependent innate responses in a manner independent of a type III secreted OspG orthologue

(2009) R. Nobe et al.   MICROBIOLOGY-SGM

A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKγ to dampen the host NF-κB-mediated inflammatory response

(2009) Hiroshi Ashida et al.   NATURE CELL BIOLOGY

NF-κB signaling mediates the induction of MTA1 by hepatitis B virus transactivator protein HBx

(2009) T M Bui-Nguyen et al.   ONCOGENE

Kaposi's sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 suppresses CXCR4 expression by upregulating miR-146a

(2009) V Punj et al.   ONCOGENE

A Legionella type IV effector activates the NF- B pathway by phosphorylating the I B family of inhibitors

(2009) J. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic screening of variola virus reveals a unique NF- B inhibitor that is highly conserved among pathogenic orthopoxviruses

(2009) M. R. Mohamed et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential NF- B pathways induction by Lactobacillus plantarum in the duodenum of healthy humans correlating with immune tolerance

(2009) P. van Baarlen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct functions of HTLV-1 Tax1 from HTLV-2 Tax2 contribute key roles to viral pathogenesis

(2009) Masaya Higuchi et al.   Retrovirology

Bacterial Effector Binding to Ribosomal Protein S3 Subverts NF-κB Function

(2009) Xiaofei Gao et al.   PLoS Pathogens

Rotavirus NSP1 Inhibits NFκB Activation by Inducing Proteasome-Dependent Degradation of β-TrCP: A Novel Mechanism of IFN Antagonism

(2009) Joel W. Graff et al.   PLoS Pathogens

Co-Regulation of NF-κB and Inflammasome-Mediated Inflammatory Responses by Myxoma Virus Pyrin Domain-Containing Protein M013

(2009) Masmudur M. Rahman et al.   PLoS Pathogens

Deletions in the Repertoire of Pseudomonas syringae pv. tomato DC3000 Type III Secretion Effector Genes Reveal Functional Overlap among Effectors

(2009) Brian H. Kvitko et al.   PLoS Pathogens

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

Toll-Like Receptor 6 Drives Differentiation of Tolerogenic Dendritic Cells and Contributes to LcrV-Mediated Plague Pathogenesis

(2008) R. William DePaolo et al.   Cell Host & Microbe

Probiotic Lactobacillus reuteri promotes TNF-induced apoptosis in human myeloid leukemia-derived cells by modulation of NF-κB and MAPK signalling

(2008) Chandra Iyer et al.   CELLULAR MICROBIOLOGY

Involvement of HVEM receptor in activation of nuclear factor κB by herpes simplex virus 1 glycoprotein D

(2008) Maria Teresa Sciortino et al.   CELLULAR MICROBIOLOGY

ChlaDub1 ofChlamydia trachomatissuppresses NF-κB activation and inhibits IκBα ubiquitination and degradation

(2008) Gaëlle Le Negrate et al.   CELLULAR MICROBIOLOGY

Probiotics as prevention and treatment for diarrhea

(2008) Alfredo Guarino et al.   CURRENT OPINION IN GASTROENTEROLOGY

Crosstalk via the NF-κB signaling system

(2008) Soumen Basak et al.   CYTOKINE & GROWTH FACTOR REVIEWS

HSV-1 ICP27 suppresses NF-κB activity by stabilizing IκBα

(2008) Jin Chul Kim et al.   FEBS LETTERS

The IκB kinase complex: master regulator of NF-κB signaling

(2008) Laura A. Solt et al.   IMMUNOLOGIC RESEARCH

The Npro product of classical swine fever virus interacts with I B , the NF- B inhibitor

(2008) V. Doceul et al.   JOURNAL OF GENERAL VIROLOGY

Hantaan Virus Nucleocapsid Protein Binds to Importin   Proteins and Inhibits Tumor Necrosis Factor Alpha-Induced Activation of Nuclear Factor Kappa B

(2008) S. L. Taylor et al.   JOURNAL OF VIROLOGY

Kaposi's Sarcoma-Associated Herpesvirus Latent Gene vFLIP Inhibits Viral Lytic Replication through NF- B-Mediated Suppression of the AP-1 Pathway: a Novel Mechanism of Virus Control of Latency

(2008) F.-C. Ye et al.   JOURNAL OF VIROLOGY

West Nile Virus Nonstructural Protein 1 Inhibits TLR3 Signal Transduction

(2008) J. R. Wilson et al.   JOURNAL OF VIROLOGY

Crystal Structure of a vFlip-IKKγ Complex: Insights into Viral Activation of the IKK Signalosome

(2008) Claire Bagnéris et al.   MOLECULAR CELL

A nuclear role for Kaposi's sarcoma-associated herpesvirus-encoded K13 protein in gene regulation

(2008) H Matta et al.   ONCOGENE

Modulation of the NF-κB Pathway by Bordetella pertussis Filamentous Hemagglutinin

(2008) Tzvia Abramson et al.   PLoS One

Inhibition of IκB Kinase by Vaccinia Virus Virulence Factor B14

(2008) Ron A.-J. Chen et al.   PLoS Pathogens

Inhibition of proinflammatory and innate immune signaling pathways by a cytomegalovirus RIP1-interacting protein

(2008) C. Mack et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Herpesvirus tegument protein activates NF- B signaling through the TRAF6 adaptor protein

(2008) X. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of Gene Expression via Disruption of NF- B Signaling by a Bacterial Small Molecule

(2008) V. V. Kravchenko et al.   SCIENCE

HCMV IL-10 Suppresses Cytokine Expression in Monocytes Through Inhibition of Nuclear Factor-κB

(2008) James Nachtwey et al.   VIRAL IMMUNOLOGY

Vaccinia Virus Proteins A52 and B14 Share a Bcl-2–Like Fold but Have Evolved to Inhibit NF-κB rather than Apoptosis

(2008) Stephen C. Graham et al.   PLoS Pathogens

The interplay between viruses and innate immune signaling: Recent insights and therapeutic opportunities

(2007) Leonie Unterholzner et al.   BIOCHEMICAL PHARMACOLOGY